Figure 4.
 Availability of GFA for the selection of prognostic miRNAs in the development of cancer survival prediction models: TCGA glioblastoma study. ( A ) Analytical outline of survival prediction using TCGA glioblastoma data sets. ( B ) Examples of Kaplan–Meier plots representing survival probabilities according to low or high levels of risk scores developed by (i) the ‘expression level-based’ strategy and (ii) the ‘expression level/GFA-based’ strategy in a training set and a test set. ( C ) Likelihood ratio of survival prediction models developed by (i) the ‘expression level-based’ strategy and (ii) the ‘expression level/GFA-based’ strategy in training sets and test sets. Positive numbers indicate that the model fits the data better. Results with five randomizations are shown. ( D ) Time-dependent prediction errors of survival prediction models developed by (i) the ‘expression level-based’ strategy and (ii) the ‘expression level/GFA-based’ strategy in training sets and test sets. Average results with five randomizations are shown.

Availability of GFA for the selection of prognostic miRNAs in the development of cancer survival prediction models: TCGA glioblastoma study. ( A ) Analytical outline of survival prediction using TCGA glioblastoma data sets. ( B ) Examples of Kaplan–Meier plots representing survival probabilities according to low or high levels of risk scores developed by (i) the ‘expression level-based’ strategy and (ii) the ‘expression level/GFA-based’ strategy in a training set and a test set. ( C ) Likelihood ratio of survival prediction models developed by (i) the ‘expression level-based’ strategy and (ii) the ‘expression level/GFA-based’ strategy in training sets and test sets. Positive numbers indicate that the model fits the data better. Results with five randomizations are shown. ( D ) Time-dependent prediction errors of survival prediction models developed by (i) the ‘expression level-based’ strategy and (ii) the ‘expression level/GFA-based’ strategy in training sets and test sets. Average results with five randomizations are shown.

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