Blood levels of miRNAs in six definite ARVC patients and six normal subjects in miRNA array. (A) Evaluation of up-regulated or down-regulated miRNA. A total of 84 miRNAs were evaluated in definite ARVC patients compared with normal subjects. (B) The levels of 11 miRNAs were found to be up-regulated in definite ARVC patients. (C) The levels of six miRNAs were found to be down-regulated in definite ARVC patients. Graphs B and C depict fold change of miRNAs in the definite ARVC patients compared with normal subjects. ARVC, arrhythmogenic right ventricular cardiomyopathy; miRNA, microRNA.