Evaluating the candidate PIGS difference in log serum neutralizing antibodies G4 from baseline to after the third dose by trial and overall. The solid black line is the overall estimate of |$-$|log(risk|$_1$|/risk|$_0$|⁠) (negative log risk ratio) and the gray ribbon indicates the prediction interval based on |$\widetilde{D}$|⁠. The labeled curves are the estimates within each of the sub-regions/trials.