(A) 66-year-old female. Typical angina. Left: Coronary CTA, moderate stenosis in RCA and LAD (arrows). Right: FFR_CT 0.85 (RCA) and 0.90 (LAD). OMT was recommended. (B) 61-year-old male. Typical angina. Left: Coronary CTA, moderate stenosis in RCA, LAD, and CX (arrows). Centre: FFR_CT 0.91 (RCA), 0.86 (LAD), 0.55 (CX). The patient was referred to ICA (Right): CX was stented and FFR was measured: 0.84 (LAD) and 0.90 (RCA). CTA, CT angiography; ICA, invasive coronary angiography; OMT, optimal medical treatment; FFR_CT, prescribed coronary CTA derived fractional flow reserve; RCA, right coronary artery; LAD, left anterior descending coronary artery; CX, circumflex coronary artery.