Lipids, lipoproteins, and apolipoproteins as part of standard and expanded lipid profiles. Standard lipid profiles consist of triglycerides and total, low-density lipoprotein, and high-density lipoprotein cholesterol; however, a standard lipid profile could also report calculated remnant cholesterol and calculated non-high-density lipoprotein cholesterol as these come at no additional cost. Calculated remnant cholesterol is non-fasting total cholesterol minus low-density lipoprotein cholesterol minus high-density lipoprotein cholesterol. Calculated non-high-density lipoprotein cholesterol is total cholesterol minus high-density lipoprotein cholesterol. Lipoprotein(a) should be measured at least once in every individual screened for cardiovascular risk in order to detect potentially high concentrations of this genetic risk factor. Finally, apolipoprotein B and apolipoprotein A1 can be used as alternatives to non-high-density lipoprotein and high-density lipoprotein cholesterol, but these measurements come at an extra cost. Figure designed by Prof. B.G. Nordestgaard.
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