Table 1.
Open in new tab

Demographic and Baseline Characteristics of the Randomized Patients

VariableArterolane Maleate–Piperaquine Phosphate (n = 571)Artemether- Lumefantrine (n = 288)
Sex, No. (%)
 Male286 (50.1)161 (55.9)
 Female285 (49.9)127 (44.1)
Age, mo
 Mean70.4986.53
 Range6.0–1447–149
Age 6 mo to <2 y
 No.8615
 Mean, mo16.9316.73
 Range, mo6–237–22
Age 2 y to <6 y
 No.21288
 Mean ± SD, mo47.54 ± 13.8044.67
 Range, mo24–7124–70
Age 6–12 y
 No.273185
 Mean, mo105.17112.10
 Range, mo72–14472–149
Race
 Asian65 (11.4)36 (12.5)
 African506 (88.6)252 (87.5)
Weight, kg
 Mean18.520.9
 Range6.3–38.66–34.9
Weight 5 kg to <15 kg
 No.19875
 Mean ± SD11.411.8
 Range6.3–14.96–14.8
Weight 15 kg to <25 kg
 No.250107
 Mean ± SD18.919.3
 Range15–24.915–24.6
Weight 25 kg to <35 kg
 No.120106
 Mean ± SD29.029.0
 Range25–34.925–34.9
Weight ≥35 kg
 No.30
 Mean ± SD6.80
 Range35–38.600
Height, cm
 Mean ± SD111.4 ± 21.96117.5 ± 20.39
 Range60–19366–160
P. falciparum asexual parasites/µL at day 0 screening
 Mean ± SD33973.0 ± 30466.0533927.4 ± 30666.20
 Median24623.023920.0
Temperature, °C, at day 0 screening
 Mean ± SD38.4 ± 1.0738.3 ± 1.03
 Median38.438.3
History of fever at day 0 screening
 Yes567 (99.3)286 (99.3)
 No4 (0.7)2 (0.7)
P. falciparum gametocytes/uL at day 0 screening
 Mean ± SD37.53 ± 520.1313.72 ± 103.41
Zero count of gametocytes
No. (%)535 (93.7)278 (96.5)
VariableArterolane Maleate–Piperaquine Phosphate (n = 571)Artemether- Lumefantrine (n = 288)
Sex, No. (%)
 Male286 (50.1)161 (55.9)
 Female285 (49.9)127 (44.1)
Age, mo
 Mean70.4986.53
 Range6.0–1447–149
Age 6 mo to <2 y
 No.8615
 Mean, mo16.9316.73
 Range, mo6–237–22
Age 2 y to <6 y
 No.21288
 Mean ± SD, mo47.54 ± 13.8044.67
 Range, mo24–7124–70
Age 6–12 y
 No.273185
 Mean, mo105.17112.10
 Range, mo72–14472–149
Race
 Asian65 (11.4)36 (12.5)
 African506 (88.6)252 (87.5)
Weight, kg
 Mean18.520.9
 Range6.3–38.66–34.9
Weight 5 kg to <15 kg
 No.19875
 Mean ± SD11.411.8
 Range6.3–14.96–14.8
Weight 15 kg to <25 kg
 No.250107
 Mean ± SD18.919.3
 Range15–24.915–24.6
Weight 25 kg to <35 kg
 No.120106
 Mean ± SD29.029.0
 Range25–34.925–34.9
Weight ≥35 kg
 No.30
 Mean ± SD6.80
 Range35–38.600
Height, cm
 Mean ± SD111.4 ± 21.96117.5 ± 20.39
 Range60–19366–160
P. falciparum asexual parasites/µL at day 0 screening
 Mean ± SD33973.0 ± 30466.0533927.4 ± 30666.20
 Median24623.023920.0
Temperature, °C, at day 0 screening
 Mean ± SD38.4 ± 1.0738.3 ± 1.03
 Median38.438.3
History of fever at day 0 screening
 Yes567 (99.3)286 (99.3)
 No4 (0.7)2 (0.7)
P. falciparum gametocytes/uL at day 0 screening
 Mean ± SD37.53 ± 520.1313.72 ± 103.41
Zero count of gametocytes
No. (%)535 (93.7)278 (96.5)

Abbreviation: SD, standard deviation.

Table 1.
Open in new tab

Demographic and Baseline Characteristics of the Randomized Patients

VariableArterolane Maleate–Piperaquine Phosphate (n = 571)Artemether- Lumefantrine (n = 288)
Sex, No. (%)
 Male286 (50.1)161 (55.9)
 Female285 (49.9)127 (44.1)
Age, mo
 Mean70.4986.53
 Range6.0–1447–149
Age 6 mo to <2 y
 No.8615
 Mean, mo16.9316.73
 Range, mo6–237–22
Age 2 y to <6 y
 No.21288
 Mean ± SD, mo47.54 ± 13.8044.67
 Range, mo24–7124–70
Age 6–12 y
 No.273185
 Mean, mo105.17112.10
 Range, mo72–14472–149
Race
 Asian65 (11.4)36 (12.5)
 African506 (88.6)252 (87.5)
Weight, kg
 Mean18.520.9
 Range6.3–38.66–34.9
Weight 5 kg to <15 kg
 No.19875
 Mean ± SD11.411.8
 Range6.3–14.96–14.8
Weight 15 kg to <25 kg
 No.250107
 Mean ± SD18.919.3
 Range15–24.915–24.6
Weight 25 kg to <35 kg
 No.120106
 Mean ± SD29.029.0
 Range25–34.925–34.9
Weight ≥35 kg
 No.30
 Mean ± SD6.80
 Range35–38.600
Height, cm
 Mean ± SD111.4 ± 21.96117.5 ± 20.39
 Range60–19366–160
P. falciparum asexual parasites/µL at day 0 screening
 Mean ± SD33973.0 ± 30466.0533927.4 ± 30666.20
 Median24623.023920.0
Temperature, °C, at day 0 screening
 Mean ± SD38.4 ± 1.0738.3 ± 1.03
 Median38.438.3
History of fever at day 0 screening
 Yes567 (99.3)286 (99.3)
 No4 (0.7)2 (0.7)
P. falciparum gametocytes/uL at day 0 screening
 Mean ± SD37.53 ± 520.1313.72 ± 103.41
Zero count of gametocytes
No. (%)535 (93.7)278 (96.5)
VariableArterolane Maleate–Piperaquine Phosphate (n = 571)Artemether- Lumefantrine (n = 288)
Sex, No. (%)
 Male286 (50.1)161 (55.9)
 Female285 (49.9)127 (44.1)
Age, mo
 Mean70.4986.53
 Range6.0–1447–149
Age 6 mo to <2 y
 No.8615
 Mean, mo16.9316.73
 Range, mo6–237–22
Age 2 y to <6 y
 No.21288
 Mean ± SD, mo47.54 ± 13.8044.67
 Range, mo24–7124–70
Age 6–12 y
 No.273185
 Mean, mo105.17112.10
 Range, mo72–14472–149
Race
 Asian65 (11.4)36 (12.5)
 African506 (88.6)252 (87.5)
Weight, kg
 Mean18.520.9
 Range6.3–38.66–34.9
Weight 5 kg to <15 kg
 No.19875
 Mean ± SD11.411.8
 Range6.3–14.96–14.8
Weight 15 kg to <25 kg
 No.250107
 Mean ± SD18.919.3
 Range15–24.915–24.6
Weight 25 kg to <35 kg
 No.120106
 Mean ± SD29.029.0
 Range25–34.925–34.9
Weight ≥35 kg
 No.30
 Mean ± SD6.80
 Range35–38.600
Height, cm
 Mean ± SD111.4 ± 21.96117.5 ± 20.39
 Range60–19366–160
P. falciparum asexual parasites/µL at day 0 screening
 Mean ± SD33973.0 ± 30466.0533927.4 ± 30666.20
 Median24623.023920.0
Temperature, °C, at day 0 screening
 Mean ± SD38.4 ± 1.0738.3 ± 1.03
 Median38.438.3
History of fever at day 0 screening
 Yes567 (99.3)286 (99.3)
 No4 (0.7)2 (0.7)
P. falciparum gametocytes/uL at day 0 screening
 Mean ± SD37.53 ± 520.1313.72 ± 103.41
Zero count of gametocytes
No. (%)535 (93.7)278 (96.5)

Abbreviation: SD, standard deviation.

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