Table 2.

Risk Ratios of the Effect of Central Venous Catheters With or Without Impregnation on Catheter-Related Bloodstream Infection

MNR0.26 (.11–.65)0.25 (.14–.48)
0.71 (.23–2.14)HEP1.29 (.30–5.66)0.23 (.07–.72)
0.50 (.24–1.04)0.71 (.25–1.99)SIL0.56 (.39–.81)
0.47 (.16–1.37)0.66 (.18–2.42)0.93 (.34–2.54)BZK0.78 (.33–1.81)
0.51 (.01–27.00)0.73 (.01–40.80)1.02 (.02–52.42)1.10 (.02–61.15)CFZ
0.42 (.19–.92)0.59 (.20–1.74)0.84 (.41–1.69)0.90 (.33–2.46)0.82 (.02–42.75)5FU0.92 (.67–1.25)
0.42 (.13–1.31)0.59 (.15–2.30)0.83 (.29–2.41)0.89 (.24–3.40)0.82 (.01–46.16)1.00 (.32–3.07)SIC0.62 (.25–1.55)
0.38 (.09–1.56)0.54 (.11–2.63)0.76 (.20–2.89)0.8 (.17–3.90)0.7 (.01–45.62)0.91 (.23–3.66)0.91 (.18–4.53)TEC0.75 (.22–2.52)
0.32 (.01–17.12)0.45 (.01–25.87)0.64 (.01–33.25)0.69 (.01–38.77)0.63 (.00–160.57)0.77 (.01–40.60)0.77 (.01–44.00)0.84 (.01–52.36)MCR
0.38 (.21–.71)0.54 (.21–1.41)0.77 (.46–1.27)0.82 (.34–1.98)0.75 (.01–37.96)0.92 (.56–1.50)0.92 (.33–2.52)1.01 (.27–3.71)1.20 (.02–61.50)CSS0.73 (.57–.94)
0.37 (.14–1.00)0.53 (.16–1.79)0.74 (.31–1.77)0.79 (.24–2.64)0.72 (.01–39.24)0.89 (.34–2.33)0.89 (.25–3.10)0.98 (.22–4.32)1.16 (.02–63.56)0.97 (.42–2.23)SPC0.79 (.40–1.56)
0.29 (.16–.52)0.41 (.16–1.04)0.57 (.38–.86)0.61 (.24–1.53)0.56 (.01–27.98)0.68 (.39–1.21)0.68 (.26–1.82)0.75 (.21–2.67)0.89 (.02–45.33)0.74 (.56–1.00)0.77 (.35–1.67)NO0.43 (.13–1.37)
0.12 (.03–0.47)0.17 (.04–.80)0.25 (.07–.87)0.26 (.06–1.19)0.24 (.00–14.43)0.29 (.08–1.11)0.29 (.06–1.38)0.32 (.06–1.86)0.38 (.01–23.36)0.32 (.09–1.10)0.33 (.08–1.38)0.43 (.13–1.43)CHX
89.774.962.456.853.350.850.345.845.444.344.024.08.4
MNR0.26 (.11–.65)0.25 (.14–.48)
0.71 (.23–2.14)HEP1.29 (.30–5.66)0.23 (.07–.72)
0.50 (.24–1.04)0.71 (.25–1.99)SIL0.56 (.39–.81)
0.47 (.16–1.37)0.66 (.18–2.42)0.93 (.34–2.54)BZK0.78 (.33–1.81)
0.51 (.01–27.00)0.73 (.01–40.80)1.02 (.02–52.42)1.10 (.02–61.15)CFZ
0.42 (.19–.92)0.59 (.20–1.74)0.84 (.41–1.69)0.90 (.33–2.46)0.82 (.02–42.75)5FU0.92 (.67–1.25)
0.42 (.13–1.31)0.59 (.15–2.30)0.83 (.29–2.41)0.89 (.24–3.40)0.82 (.01–46.16)1.00 (.32–3.07)SIC0.62 (.25–1.55)
0.38 (.09–1.56)0.54 (.11–2.63)0.76 (.20–2.89)0.8 (.17–3.90)0.7 (.01–45.62)0.91 (.23–3.66)0.91 (.18–4.53)TEC0.75 (.22–2.52)
0.32 (.01–17.12)0.45 (.01–25.87)0.64 (.01–33.25)0.69 (.01–38.77)0.63 (.00–160.57)0.77 (.01–40.60)0.77 (.01–44.00)0.84 (.01–52.36)MCR
0.38 (.21–.71)0.54 (.21–1.41)0.77 (.46–1.27)0.82 (.34–1.98)0.75 (.01–37.96)0.92 (.56–1.50)0.92 (.33–2.52)1.01 (.27–3.71)1.20 (.02–61.50)CSS0.73 (.57–.94)
0.37 (.14–1.00)0.53 (.16–1.79)0.74 (.31–1.77)0.79 (.24–2.64)0.72 (.01–39.24)0.89 (.34–2.33)0.89 (.25–3.10)0.98 (.22–4.32)1.16 (.02–63.56)0.97 (.42–2.23)SPC0.79 (.40–1.56)
0.29 (.16–.52)0.41 (.16–1.04)0.57 (.38–.86)0.61 (.24–1.53)0.56 (.01–27.98)0.68 (.39–1.21)0.68 (.26–1.82)0.75 (.21–2.67)0.89 (.02–45.33)0.74 (.56–1.00)0.77 (.35–1.67)NO0.43 (.13–1.37)
0.12 (.03–0.47)0.17 (.04–.80)0.25 (.07–.87)0.26 (.06–1.19)0.24 (.00–14.43)0.29 (.08–1.11)0.29 (.06–1.38)0.32 (.06–1.86)0.38 (.01–23.36)0.32 (.09–1.10)0.33 (.08–1.38)0.43 (.13–1.43)CHX
89.774.962.456.853.350.850.345.845.444.344.024.08.4

Impregnations are ordered according to surface under the cumulative ranking curve (SUCRA). Estimates were presented as risk ratio (95% confidence interval). Results of direct comparisons were listed in the upper triangle where the estimation was calculated as the column-defining treatment compared with the row-defining treatment. Network estimates were listed in the lower triangle where the estimation was calculated as the row-defining treatment compared with the column-defining treatment. The SUCRA values are presented in the bottom row of the table. The larger the SUCRA value, the better the treatment. Significant results are shown in bold.

Abbreviations: BZK, benzalkonium; CFZ, cefazolin; CHX, chlorhexidine; CSS, chlorhexidine-silver sulfadiazine; 5FU, 5-fluorouracil; HEP, heparin; MCR, miconazole-rifampicin; MNR, minocycline-rifampicin; NO, no impregnation; SIC, silver-impregnated cuff; SIL, silver; SPC, silver-platinum-carbon; TEC, teicoplanin.

Table 2.

Risk Ratios of the Effect of Central Venous Catheters With or Without Impregnation on Catheter-Related Bloodstream Infection

MNR0.26 (.11–.65)0.25 (.14–.48)
0.71 (.23–2.14)HEP1.29 (.30–5.66)0.23 (.07–.72)
0.50 (.24–1.04)0.71 (.25–1.99)SIL0.56 (.39–.81)
0.47 (.16–1.37)0.66 (.18–2.42)0.93 (.34–2.54)BZK0.78 (.33–1.81)
0.51 (.01–27.00)0.73 (.01–40.80)1.02 (.02–52.42)1.10 (.02–61.15)CFZ
0.42 (.19–.92)0.59 (.20–1.74)0.84 (.41–1.69)0.90 (.33–2.46)0.82 (.02–42.75)5FU0.92 (.67–1.25)
0.42 (.13–1.31)0.59 (.15–2.30)0.83 (.29–2.41)0.89 (.24–3.40)0.82 (.01–46.16)1.00 (.32–3.07)SIC0.62 (.25–1.55)
0.38 (.09–1.56)0.54 (.11–2.63)0.76 (.20–2.89)0.8 (.17–3.90)0.7 (.01–45.62)0.91 (.23–3.66)0.91 (.18–4.53)TEC0.75 (.22–2.52)
0.32 (.01–17.12)0.45 (.01–25.87)0.64 (.01–33.25)0.69 (.01–38.77)0.63 (.00–160.57)0.77 (.01–40.60)0.77 (.01–44.00)0.84 (.01–52.36)MCR
0.38 (.21–.71)0.54 (.21–1.41)0.77 (.46–1.27)0.82 (.34–1.98)0.75 (.01–37.96)0.92 (.56–1.50)0.92 (.33–2.52)1.01 (.27–3.71)1.20 (.02–61.50)CSS0.73 (.57–.94)
0.37 (.14–1.00)0.53 (.16–1.79)0.74 (.31–1.77)0.79 (.24–2.64)0.72 (.01–39.24)0.89 (.34–2.33)0.89 (.25–3.10)0.98 (.22–4.32)1.16 (.02–63.56)0.97 (.42–2.23)SPC0.79 (.40–1.56)
0.29 (.16–.52)0.41 (.16–1.04)0.57 (.38–.86)0.61 (.24–1.53)0.56 (.01–27.98)0.68 (.39–1.21)0.68 (.26–1.82)0.75 (.21–2.67)0.89 (.02–45.33)0.74 (.56–1.00)0.77 (.35–1.67)NO0.43 (.13–1.37)
0.12 (.03–0.47)0.17 (.04–.80)0.25 (.07–.87)0.26 (.06–1.19)0.24 (.00–14.43)0.29 (.08–1.11)0.29 (.06–1.38)0.32 (.06–1.86)0.38 (.01–23.36)0.32 (.09–1.10)0.33 (.08–1.38)0.43 (.13–1.43)CHX
89.774.962.456.853.350.850.345.845.444.344.024.08.4
MNR0.26 (.11–.65)0.25 (.14–.48)
0.71 (.23–2.14)HEP1.29 (.30–5.66)0.23 (.07–.72)
0.50 (.24–1.04)0.71 (.25–1.99)SIL0.56 (.39–.81)
0.47 (.16–1.37)0.66 (.18–2.42)0.93 (.34–2.54)BZK0.78 (.33–1.81)
0.51 (.01–27.00)0.73 (.01–40.80)1.02 (.02–52.42)1.10 (.02–61.15)CFZ
0.42 (.19–.92)0.59 (.20–1.74)0.84 (.41–1.69)0.90 (.33–2.46)0.82 (.02–42.75)5FU0.92 (.67–1.25)
0.42 (.13–1.31)0.59 (.15–2.30)0.83 (.29–2.41)0.89 (.24–3.40)0.82 (.01–46.16)1.00 (.32–3.07)SIC0.62 (.25–1.55)
0.38 (.09–1.56)0.54 (.11–2.63)0.76 (.20–2.89)0.8 (.17–3.90)0.7 (.01–45.62)0.91 (.23–3.66)0.91 (.18–4.53)TEC0.75 (.22–2.52)
0.32 (.01–17.12)0.45 (.01–25.87)0.64 (.01–33.25)0.69 (.01–38.77)0.63 (.00–160.57)0.77 (.01–40.60)0.77 (.01–44.00)0.84 (.01–52.36)MCR
0.38 (.21–.71)0.54 (.21–1.41)0.77 (.46–1.27)0.82 (.34–1.98)0.75 (.01–37.96)0.92 (.56–1.50)0.92 (.33–2.52)1.01 (.27–3.71)1.20 (.02–61.50)CSS0.73 (.57–.94)
0.37 (.14–1.00)0.53 (.16–1.79)0.74 (.31–1.77)0.79 (.24–2.64)0.72 (.01–39.24)0.89 (.34–2.33)0.89 (.25–3.10)0.98 (.22–4.32)1.16 (.02–63.56)0.97 (.42–2.23)SPC0.79 (.40–1.56)
0.29 (.16–.52)0.41 (.16–1.04)0.57 (.38–.86)0.61 (.24–1.53)0.56 (.01–27.98)0.68 (.39–1.21)0.68 (.26–1.82)0.75 (.21–2.67)0.89 (.02–45.33)0.74 (.56–1.00)0.77 (.35–1.67)NO0.43 (.13–1.37)
0.12 (.03–0.47)0.17 (.04–.80)0.25 (.07–.87)0.26 (.06–1.19)0.24 (.00–14.43)0.29 (.08–1.11)0.29 (.06–1.38)0.32 (.06–1.86)0.38 (.01–23.36)0.32 (.09–1.10)0.33 (.08–1.38)0.43 (.13–1.43)CHX
89.774.962.456.853.350.850.345.845.444.344.024.08.4

Impregnations are ordered according to surface under the cumulative ranking curve (SUCRA). Estimates were presented as risk ratio (95% confidence interval). Results of direct comparisons were listed in the upper triangle where the estimation was calculated as the column-defining treatment compared with the row-defining treatment. Network estimates were listed in the lower triangle where the estimation was calculated as the row-defining treatment compared with the column-defining treatment. The SUCRA values are presented in the bottom row of the table. The larger the SUCRA value, the better the treatment. Significant results are shown in bold.

Abbreviations: BZK, benzalkonium; CFZ, cefazolin; CHX, chlorhexidine; CSS, chlorhexidine-silver sulfadiazine; 5FU, 5-fluorouracil; HEP, heparin; MCR, miconazole-rifampicin; MNR, minocycline-rifampicin; NO, no impregnation; SIC, silver-impregnated cuff; SIL, silver; SPC, silver-platinum-carbon; TEC, teicoplanin.

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