Conditions associated with hypercortisolism in the absence of Cushing's syndromea
| Conditions . |
|---|
| Some clinical features of Cushing's syndrome may be present |
| Pregnancy |
| Depression and other psychiatric conditions |
| Alcohol dependence |
| Glucocorticoid resistance |
| Morbid obesity |
| Poorly controlled diabetes mellitus |
| Unlikely to have any clinical features of Cushing's syndrome |
| Physical stress (hospitalization, surgery, pain) |
| Malnutrition, anorexia nervosa |
| Intense chronic exercise |
| Hypothalamic amenorrhea |
| CBG excess (increased serum but not urine cortisol) |
| Conditions . |
|---|
| Some clinical features of Cushing's syndrome may be present |
| Pregnancy |
| Depression and other psychiatric conditions |
| Alcohol dependence |
| Glucocorticoid resistance |
| Morbid obesity |
| Poorly controlled diabetes mellitus |
| Unlikely to have any clinical features of Cushing's syndrome |
| Physical stress (hospitalization, surgery, pain) |
| Malnutrition, anorexia nervosa |
| Intense chronic exercise |
| Hypothalamic amenorrhea |
| CBG excess (increased serum but not urine cortisol) |
Whereas Cushing's syndrome is unlikely in these conditions, it may rarely be present. If there is a high clinical index of suspicion, the patient should undergo testing, particularly those within the first group.
Conditions associated with hypercortisolism in the absence of Cushing's syndromea
| Conditions . |
|---|
| Some clinical features of Cushing's syndrome may be present |
| Pregnancy |
| Depression and other psychiatric conditions |
| Alcohol dependence |
| Glucocorticoid resistance |
| Morbid obesity |
| Poorly controlled diabetes mellitus |
| Unlikely to have any clinical features of Cushing's syndrome |
| Physical stress (hospitalization, surgery, pain) |
| Malnutrition, anorexia nervosa |
| Intense chronic exercise |
| Hypothalamic amenorrhea |
| CBG excess (increased serum but not urine cortisol) |
| Conditions . |
|---|
| Some clinical features of Cushing's syndrome may be present |
| Pregnancy |
| Depression and other psychiatric conditions |
| Alcohol dependence |
| Glucocorticoid resistance |
| Morbid obesity |
| Poorly controlled diabetes mellitus |
| Unlikely to have any clinical features of Cushing's syndrome |
| Physical stress (hospitalization, surgery, pain) |
| Malnutrition, anorexia nervosa |
| Intense chronic exercise |
| Hypothalamic amenorrhea |
| CBG excess (increased serum but not urine cortisol) |
Whereas Cushing's syndrome is unlikely in these conditions, it may rarely be present. If there is a high clinical index of suspicion, the patient should undergo testing, particularly those within the first group.
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