Table 1

Baseline Characteristics of Study Sample

CharacteristicTotal (n = 643)Euthyroid (n = 534)
Age, y, mean (sd)85.5 (0.4)85.5 (0.4)
Male, % (n)42.0 (270)43.6 (233)
BMI, mean (sd)24.4 (4.4)24.5 (4.5)
Current smoker, % (n)5.6 (36)5.3 (28)
Basic education, % (n)63.6 (404)64.2 (339)
Living in care home, % (n)8.7 (56)8.6 (46)
Medical history, % (n)
 Diabetes14.1 (91)14.2 (76)
 Hypertension58.2 (374)59.0 (315)
 IHD34.4 (221)37.3 (196)
 Stroke13.8 (89)13.7 (73)
 Cancer6.4 (41)6.2 (33)
Disease count, median (IQR)4 (3–6)4 (3–6)
Disability score, median (IQR)3 (1–7)3 (1–7)
MMSE score, median (IQR)28 (25–29)28 (25–29)
Fair or poor self-rated health, % (n)19.9 (120)20.9 (110)
Survival time, mo, median (IQR)65.6 (32.6–92.6)64.6 (32.4–91.1)
Deaths, % (n)68.4 (440)70.2 (375)
Cardiovascular deaths, % (n)39.2 (252)40.6 (217)
TSHa, mU/L1.87 (0.27–6.53)1.73 (0.58–3.80)
FT3a, pmol/L4.54 (3.60–5.5)4.52 (3.60–5.40)
FT4a, pmol/L15.20 (11.0–21.0)15.24 (11.0–20.0)
rT3a, nmol/L0.40 (0.25–0.67)0.40 (0.26–0.67)
TPOAbs positive, % (n)15.9 (102)12.6 (67)
Albumina, g/L40.03 (33.00–46.00)40.03 (33.00–46.00)
C reactive proteina, mg/L2.65 (0.30–52.20)2.67 (0.30–52.20)
Overt hypothyroid0.9 (6)
Subclinical hypothyroid12.3 (79)
Euthyroid83.1 (534)534 (100)
Subclinical hyperthyroid2.9 (19)
Overt hyperthyroid0.8 (5)
CharacteristicTotal (n = 643)Euthyroid (n = 534)
Age, y, mean (sd)85.5 (0.4)85.5 (0.4)
Male, % (n)42.0 (270)43.6 (233)
BMI, mean (sd)24.4 (4.4)24.5 (4.5)
Current smoker, % (n)5.6 (36)5.3 (28)
Basic education, % (n)63.6 (404)64.2 (339)
Living in care home, % (n)8.7 (56)8.6 (46)
Medical history, % (n)
 Diabetes14.1 (91)14.2 (76)
 Hypertension58.2 (374)59.0 (315)
 IHD34.4 (221)37.3 (196)
 Stroke13.8 (89)13.7 (73)
 Cancer6.4 (41)6.2 (33)
Disease count, median (IQR)4 (3–6)4 (3–6)
Disability score, median (IQR)3 (1–7)3 (1–7)
MMSE score, median (IQR)28 (25–29)28 (25–29)
Fair or poor self-rated health, % (n)19.9 (120)20.9 (110)
Survival time, mo, median (IQR)65.6 (32.6–92.6)64.6 (32.4–91.1)
Deaths, % (n)68.4 (440)70.2 (375)
Cardiovascular deaths, % (n)39.2 (252)40.6 (217)
TSHa, mU/L1.87 (0.27–6.53)1.73 (0.58–3.80)
FT3a, pmol/L4.54 (3.60–5.5)4.52 (3.60–5.40)
FT4a, pmol/L15.20 (11.0–21.0)15.24 (11.0–20.0)
rT3a, nmol/L0.40 (0.25–0.67)0.40 (0.26–0.67)
TPOAbs positive, % (n)15.9 (102)12.6 (67)
Albumina, g/L40.03 (33.00–46.00)40.03 (33.00–46.00)
C reactive proteina, mg/L2.65 (0.30–52.20)2.67 (0.30–52.20)
Overt hypothyroid0.9 (6)
Subclinical hypothyroid12.3 (79)
Euthyroid83.1 (534)534 (100)
Subclinical hyperthyroid2.9 (19)
Overt hyperthyroid0.8 (5)

Abbreviations: IHD, ischemic heart disease; IQR, interquartile range; TPOAbs, thyroid peroxidase antibodies.

a

Geometric mean, 2.5–97.5th percentiles

Table 1

Baseline Characteristics of Study Sample

CharacteristicTotal (n = 643)Euthyroid (n = 534)
Age, y, mean (sd)85.5 (0.4)85.5 (0.4)
Male, % (n)42.0 (270)43.6 (233)
BMI, mean (sd)24.4 (4.4)24.5 (4.5)
Current smoker, % (n)5.6 (36)5.3 (28)
Basic education, % (n)63.6 (404)64.2 (339)
Living in care home, % (n)8.7 (56)8.6 (46)
Medical history, % (n)
 Diabetes14.1 (91)14.2 (76)
 Hypertension58.2 (374)59.0 (315)
 IHD34.4 (221)37.3 (196)
 Stroke13.8 (89)13.7 (73)
 Cancer6.4 (41)6.2 (33)
Disease count, median (IQR)4 (3–6)4 (3–6)
Disability score, median (IQR)3 (1–7)3 (1–7)
MMSE score, median (IQR)28 (25–29)28 (25–29)
Fair or poor self-rated health, % (n)19.9 (120)20.9 (110)
Survival time, mo, median (IQR)65.6 (32.6–92.6)64.6 (32.4–91.1)
Deaths, % (n)68.4 (440)70.2 (375)
Cardiovascular deaths, % (n)39.2 (252)40.6 (217)
TSHa, mU/L1.87 (0.27–6.53)1.73 (0.58–3.80)
FT3a, pmol/L4.54 (3.60–5.5)4.52 (3.60–5.40)
FT4a, pmol/L15.20 (11.0–21.0)15.24 (11.0–20.0)
rT3a, nmol/L0.40 (0.25–0.67)0.40 (0.26–0.67)
TPOAbs positive, % (n)15.9 (102)12.6 (67)
Albumina, g/L40.03 (33.00–46.00)40.03 (33.00–46.00)
C reactive proteina, mg/L2.65 (0.30–52.20)2.67 (0.30–52.20)
Overt hypothyroid0.9 (6)
Subclinical hypothyroid12.3 (79)
Euthyroid83.1 (534)534 (100)
Subclinical hyperthyroid2.9 (19)
Overt hyperthyroid0.8 (5)
CharacteristicTotal (n = 643)Euthyroid (n = 534)
Age, y, mean (sd)85.5 (0.4)85.5 (0.4)
Male, % (n)42.0 (270)43.6 (233)
BMI, mean (sd)24.4 (4.4)24.5 (4.5)
Current smoker, % (n)5.6 (36)5.3 (28)
Basic education, % (n)63.6 (404)64.2 (339)
Living in care home, % (n)8.7 (56)8.6 (46)
Medical history, % (n)
 Diabetes14.1 (91)14.2 (76)
 Hypertension58.2 (374)59.0 (315)
 IHD34.4 (221)37.3 (196)
 Stroke13.8 (89)13.7 (73)
 Cancer6.4 (41)6.2 (33)
Disease count, median (IQR)4 (3–6)4 (3–6)
Disability score, median (IQR)3 (1–7)3 (1–7)
MMSE score, median (IQR)28 (25–29)28 (25–29)
Fair or poor self-rated health, % (n)19.9 (120)20.9 (110)
Survival time, mo, median (IQR)65.6 (32.6–92.6)64.6 (32.4–91.1)
Deaths, % (n)68.4 (440)70.2 (375)
Cardiovascular deaths, % (n)39.2 (252)40.6 (217)
TSHa, mU/L1.87 (0.27–6.53)1.73 (0.58–3.80)
FT3a, pmol/L4.54 (3.60–5.5)4.52 (3.60–5.40)
FT4a, pmol/L15.20 (11.0–21.0)15.24 (11.0–20.0)
rT3a, nmol/L0.40 (0.25–0.67)0.40 (0.26–0.67)
TPOAbs positive, % (n)15.9 (102)12.6 (67)
Albumina, g/L40.03 (33.00–46.00)40.03 (33.00–46.00)
C reactive proteina, mg/L2.65 (0.30–52.20)2.67 (0.30–52.20)
Overt hypothyroid0.9 (6)
Subclinical hypothyroid12.3 (79)
Euthyroid83.1 (534)534 (100)
Subclinical hyperthyroid2.9 (19)
Overt hyperthyroid0.8 (5)

Abbreviations: IHD, ischemic heart disease; IQR, interquartile range; TPOAbs, thyroid peroxidase antibodies.

a

Geometric mean, 2.5–97.5th percentiles

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