Mean ± SEM Relative mRNA Abundance in the Lungs of Sheep Fetuses Infused iv With Either Saline or Leptin (0.5 or 1.0 LEP) for 5 Days
| . | Saline (n = 6) . | 0.5 LEP (n = 10) . | 1.0 LEP (n = 7) . |
|---|---|---|---|
| Elastin | 1.00 ± 0.24 | 0.85 ± 0.16 | 1.13 ± 0.50 |
| VEGF-A | 1.00 ± 0.11 | 0.81 ± 0.14 | 0.64 ± 0.12 |
| VEGFR2 | 1.00 ± 0.23 | 0.56 ± 0.12 | 0.50 ± 0.12 |
| ACE | 1.00 ± 0.19 | 0.76 ± 0.16 | 1.02 ± 0.30 |
| PPARγ | 1.00 ± 0.17 | 0.83 ± 0.08 | 1.11 ± 0.28 |
| PTHrP | 1.00 ± 0.16 | 1.28 ± 0.27 | 0.91 ± 0.15 |
| . | Saline (n = 6) . | 0.5 LEP (n = 10) . | 1.0 LEP (n = 7) . |
|---|---|---|---|
| Elastin | 1.00 ± 0.24 | 0.85 ± 0.16 | 1.13 ± 0.50 |
| VEGF-A | 1.00 ± 0.11 | 0.81 ± 0.14 | 0.64 ± 0.12 |
| VEGFR2 | 1.00 ± 0.23 | 0.56 ± 0.12 | 0.50 ± 0.12 |
| ACE | 1.00 ± 0.19 | 0.76 ± 0.16 | 1.02 ± 0.30 |
| PPARγ | 1.00 ± 0.17 | 0.83 ± 0.08 | 1.11 ± 0.28 |
| PTHrP | 1.00 ± 0.16 | 1.28 ± 0.27 | 0.91 ± 0.15 |
Data are expressed as a fold change relative to the saline group.
Mean ± SEM Relative mRNA Abundance in the Lungs of Sheep Fetuses Infused iv With Either Saline or Leptin (0.5 or 1.0 LEP) for 5 Days
| . | Saline (n = 6) . | 0.5 LEP (n = 10) . | 1.0 LEP (n = 7) . |
|---|---|---|---|
| Elastin | 1.00 ± 0.24 | 0.85 ± 0.16 | 1.13 ± 0.50 |
| VEGF-A | 1.00 ± 0.11 | 0.81 ± 0.14 | 0.64 ± 0.12 |
| VEGFR2 | 1.00 ± 0.23 | 0.56 ± 0.12 | 0.50 ± 0.12 |
| ACE | 1.00 ± 0.19 | 0.76 ± 0.16 | 1.02 ± 0.30 |
| PPARγ | 1.00 ± 0.17 | 0.83 ± 0.08 | 1.11 ± 0.28 |
| PTHrP | 1.00 ± 0.16 | 1.28 ± 0.27 | 0.91 ± 0.15 |
| . | Saline (n = 6) . | 0.5 LEP (n = 10) . | 1.0 LEP (n = 7) . |
|---|---|---|---|
| Elastin | 1.00 ± 0.24 | 0.85 ± 0.16 | 1.13 ± 0.50 |
| VEGF-A | 1.00 ± 0.11 | 0.81 ± 0.14 | 0.64 ± 0.12 |
| VEGFR2 | 1.00 ± 0.23 | 0.56 ± 0.12 | 0.50 ± 0.12 |
| ACE | 1.00 ± 0.19 | 0.76 ± 0.16 | 1.02 ± 0.30 |
| PPARγ | 1.00 ± 0.17 | 0.83 ± 0.08 | 1.11 ± 0.28 |
| PTHrP | 1.00 ± 0.16 | 1.28 ± 0.27 | 0.91 ± 0.15 |
Data are expressed as a fold change relative to the saline group.
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