Table 2

Possible binding sites to transcription factors of gene STE13ca from C. albicans

Transcription factorFurther informationPosition from-toSCore sim.Matriz sim.Sequence
MATA1Mating factor a1−39 to −31(+)1.000.929tGATGcaac
NIT2Activator of nitrogen-regulated genes−304 to −298(−)1.000.994TATCtct
MCM1Yeast factor MCM1 cooperating with MATα factors−501 to −485(+)1.000.913atgCCTAaattgggaaa
STREMSN2/MSN4, STRE element, S. cerevisiae−841 to −833(+)1.000.980ccAGGGgat
NIT2Activator of nitrogen-regulated genes−946 to −940(+)1.000.994TATCtcc
MATA1Mating factor a1−1196 to −1188(−)1.000.947tGATGtgga
NIT2Activator of nitrogen-regulated genes−1217 to −1211(−)1.000.994TATCtca
NIT2activator of nitrogen-regulated genes−1344 to 1338(+)1.000.994TATCtct
MAT1MCHMG-BOX protein interacts with M-box site, cooperativity with HMG-Box STE11 protein−1669 to 1659(−)1.000.896gtcaTTGTttt
RAP1RAP1 (TUF1), activator or repressor depending on context−1732 to −1718(−)1.000.860aaaACCCatataaaa
Transcription factorFurther informationPosition from-toSCore sim.Matriz sim.Sequence
MATA1Mating factor a1−39 to −31(+)1.000.929tGATGcaac
NIT2Activator of nitrogen-regulated genes−304 to −298(−)1.000.994TATCtct
MCM1Yeast factor MCM1 cooperating with MATα factors−501 to −485(+)1.000.913atgCCTAaattgggaaa
STREMSN2/MSN4, STRE element, S. cerevisiae−841 to −833(+)1.000.980ccAGGGgat
NIT2Activator of nitrogen-regulated genes−946 to −940(+)1.000.994TATCtcc
MATA1Mating factor a1−1196 to −1188(−)1.000.947tGATGtgga
NIT2Activator of nitrogen-regulated genes−1217 to −1211(−)1.000.994TATCtca
NIT2activator of nitrogen-regulated genes−1344 to 1338(+)1.000.994TATCtct
MAT1MCHMG-BOX protein interacts with M-box site, cooperativity with HMG-Box STE11 protein−1669 to 1659(−)1.000.896gtcaTTGTttt
RAP1RAP1 (TUF1), activator or repressor depending on context−1732 to −1718(−)1.000.860aaaACCCatataaaa

2000 pb upstream of the starting codon (ATG) were analyzed.

S: Positive/negative strand.

Basepairs marked in bold show high information content, i.e., the matrix exhibits a high conservation at this position.

The “core sequence” of a matrix is defined as the (usually 4) consecutive highest conserved positions of the matrix.

The analysis was performed with a “core similarity” of 0.9. The maximum core similarity of 1.0 is only reached when the highest conserved bases of a matrix match exactly in the sequence. More important than the core similarity is the matrix similarity, which takes into account all bases over the whole matrix length. A perfect match to the matrix gets a score of 1.00 (each sequence position corresponds to the highest conserved nucleotide at that position in the matriz), a good match to the matriz usually has a similarity of >0.80.

Basepairs in capital letters denote the core sequence used by MatInspector.

Table 2

Possible binding sites to transcription factors of gene STE13ca from C. albicans

Transcription factorFurther informationPosition from-toSCore sim.Matriz sim.Sequence
MATA1Mating factor a1−39 to −31(+)1.000.929tGATGcaac
NIT2Activator of nitrogen-regulated genes−304 to −298(−)1.000.994TATCtct
MCM1Yeast factor MCM1 cooperating with MATα factors−501 to −485(+)1.000.913atgCCTAaattgggaaa
STREMSN2/MSN4, STRE element, S. cerevisiae−841 to −833(+)1.000.980ccAGGGgat
NIT2Activator of nitrogen-regulated genes−946 to −940(+)1.000.994TATCtcc
MATA1Mating factor a1−1196 to −1188(−)1.000.947tGATGtgga
NIT2Activator of nitrogen-regulated genes−1217 to −1211(−)1.000.994TATCtca
NIT2activator of nitrogen-regulated genes−1344 to 1338(+)1.000.994TATCtct
MAT1MCHMG-BOX protein interacts with M-box site, cooperativity with HMG-Box STE11 protein−1669 to 1659(−)1.000.896gtcaTTGTttt
RAP1RAP1 (TUF1), activator or repressor depending on context−1732 to −1718(−)1.000.860aaaACCCatataaaa
Transcription factorFurther informationPosition from-toSCore sim.Matriz sim.Sequence
MATA1Mating factor a1−39 to −31(+)1.000.929tGATGcaac
NIT2Activator of nitrogen-regulated genes−304 to −298(−)1.000.994TATCtct
MCM1Yeast factor MCM1 cooperating with MATα factors−501 to −485(+)1.000.913atgCCTAaattgggaaa
STREMSN2/MSN4, STRE element, S. cerevisiae−841 to −833(+)1.000.980ccAGGGgat
NIT2Activator of nitrogen-regulated genes−946 to −940(+)1.000.994TATCtcc
MATA1Mating factor a1−1196 to −1188(−)1.000.947tGATGtgga
NIT2Activator of nitrogen-regulated genes−1217 to −1211(−)1.000.994TATCtca
NIT2activator of nitrogen-regulated genes−1344 to 1338(+)1.000.994TATCtct
MAT1MCHMG-BOX protein interacts with M-box site, cooperativity with HMG-Box STE11 protein−1669 to 1659(−)1.000.896gtcaTTGTttt
RAP1RAP1 (TUF1), activator or repressor depending on context−1732 to −1718(−)1.000.860aaaACCCatataaaa

2000 pb upstream of the starting codon (ATG) were analyzed.

S: Positive/negative strand.

Basepairs marked in bold show high information content, i.e., the matrix exhibits a high conservation at this position.

The “core sequence” of a matrix is defined as the (usually 4) consecutive highest conserved positions of the matrix.

The analysis was performed with a “core similarity” of 0.9. The maximum core similarity of 1.0 is only reached when the highest conserved bases of a matrix match exactly in the sequence. More important than the core similarity is the matrix similarity, which takes into account all bases over the whole matrix length. A perfect match to the matrix gets a score of 1.00 (each sequence position corresponds to the highest conserved nucleotide at that position in the matriz), a good match to the matriz usually has a similarity of >0.80.

Basepairs in capital letters denote the core sequence used by MatInspector.

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