| Fungus | Cell type | Signaling pathway | References | |
| Fungus | Cell/fungus interaction | |||
| Candida albicans | Macrophages endothelial Y → M | cAMP/PKA: virulence, filamentation MAPK: virulence, filamentation Ras 1: morphogenesis/Ras 2: pseudohyphae Ras 1/Ras 2: viability Ca+2/Calmodulin: Y → M | PKC: survival, virulence MAPK/ERK 1/2/p90RSK: phagocytosis | 101,102,105,111,113,115,126 |
| Fonsecaea pedrosoi | Macrophages epithelial | PKC: invasion | PKC: attachment, invasion | 104 |
| Saccharomyces cerevisiae | Macrophages | cAMP/PKA: nutrient MAPK: nutrient GPA1/STE: mating | MAPK/ERK 1/2/p90RSK: phagocytosis | 111,115 |
| Aspergillus fumigatus | Endothelial | cAMP: virulence | cAMP/PKA: gene regulation Ras: virulence | 107 |
| Cryptococcus neoformans | Phagocytes | GPA, Rac1: mating GPA: nutrient Ras 1: virulence, filamentation | PI-3K/Ras/MEK/ERK: phagocytosis | 111,117 |
| Paracoccidioides brasiliensis | Y → M | PKA G protein, Ras cAMP, GPA: putative Rho1, SEP1, FLB1: signal, polarity, shape PKC1: putative Ca+2/Calmodulin: morphogenetic differentiation Y → M | 112,123,124 | |
| Histoplasma capsulatum | Y → M | Ca+2/Calmodulin: differentiation Y → M | 125 | |
| Fungus | Cell type | Signaling pathway | References | |
| Fungus | Cell/fungus interaction | |||
| Candida albicans | Macrophages endothelial Y → M | cAMP/PKA: virulence, filamentation MAPK: virulence, filamentation Ras 1: morphogenesis/Ras 2: pseudohyphae Ras 1/Ras 2: viability Ca+2/Calmodulin: Y → M | PKC: survival, virulence MAPK/ERK 1/2/p90RSK: phagocytosis | 101,102,105,111,113,115,126 |
| Fonsecaea pedrosoi | Macrophages epithelial | PKC: invasion | PKC: attachment, invasion | 104 |
| Saccharomyces cerevisiae | Macrophages | cAMP/PKA: nutrient MAPK: nutrient GPA1/STE: mating | MAPK/ERK 1/2/p90RSK: phagocytosis | 111,115 |
| Aspergillus fumigatus | Endothelial | cAMP: virulence | cAMP/PKA: gene regulation Ras: virulence | 107 |
| Cryptococcus neoformans | Phagocytes | GPA, Rac1: mating GPA: nutrient Ras 1: virulence, filamentation | PI-3K/Ras/MEK/ERK: phagocytosis | 111,117 |
| Paracoccidioides brasiliensis | Y → M | PKA G protein, Ras cAMP, GPA: putative Rho1, SEP1, FLB1: signal, polarity, shape PKC1: putative Ca+2/Calmodulin: morphogenetic differentiation Y → M | 112,123,124 | |
| Histoplasma capsulatum | Y → M | Ca+2/Calmodulin: differentiation Y → M | 125 | |
PKC — Protein Kinase C; cAMP — cyclic adenosine 5′ monophosphate; MAPK — mitogen activated protein kinase; PKA: cyclic AMP-dependent protein kinase; Y: yeast; M: mycelium.
| Fungus | Cell type | Signaling pathway | References | |
| Fungus | Cell/fungus interaction | |||
| Candida albicans | Macrophages endothelial Y → M | cAMP/PKA: virulence, filamentation MAPK: virulence, filamentation Ras 1: morphogenesis/Ras 2: pseudohyphae Ras 1/Ras 2: viability Ca+2/Calmodulin: Y → M | PKC: survival, virulence MAPK/ERK 1/2/p90RSK: phagocytosis | 101,102,105,111,113,115,126 |
| Fonsecaea pedrosoi | Macrophages epithelial | PKC: invasion | PKC: attachment, invasion | 104 |
| Saccharomyces cerevisiae | Macrophages | cAMP/PKA: nutrient MAPK: nutrient GPA1/STE: mating | MAPK/ERK 1/2/p90RSK: phagocytosis | 111,115 |
| Aspergillus fumigatus | Endothelial | cAMP: virulence | cAMP/PKA: gene regulation Ras: virulence | 107 |
| Cryptococcus neoformans | Phagocytes | GPA, Rac1: mating GPA: nutrient Ras 1: virulence, filamentation | PI-3K/Ras/MEK/ERK: phagocytosis | 111,117 |
| Paracoccidioides brasiliensis | Y → M | PKA G protein, Ras cAMP, GPA: putative Rho1, SEP1, FLB1: signal, polarity, shape PKC1: putative Ca+2/Calmodulin: morphogenetic differentiation Y → M | 112,123,124 | |
| Histoplasma capsulatum | Y → M | Ca+2/Calmodulin: differentiation Y → M | 125 | |
| Fungus | Cell type | Signaling pathway | References | |
| Fungus | Cell/fungus interaction | |||
| Candida albicans | Macrophages endothelial Y → M | cAMP/PKA: virulence, filamentation MAPK: virulence, filamentation Ras 1: morphogenesis/Ras 2: pseudohyphae Ras 1/Ras 2: viability Ca+2/Calmodulin: Y → M | PKC: survival, virulence MAPK/ERK 1/2/p90RSK: phagocytosis | 101,102,105,111,113,115,126 |
| Fonsecaea pedrosoi | Macrophages epithelial | PKC: invasion | PKC: attachment, invasion | 104 |
| Saccharomyces cerevisiae | Macrophages | cAMP/PKA: nutrient MAPK: nutrient GPA1/STE: mating | MAPK/ERK 1/2/p90RSK: phagocytosis | 111,115 |
| Aspergillus fumigatus | Endothelial | cAMP: virulence | cAMP/PKA: gene regulation Ras: virulence | 107 |
| Cryptococcus neoformans | Phagocytes | GPA, Rac1: mating GPA: nutrient Ras 1: virulence, filamentation | PI-3K/Ras/MEK/ERK: phagocytosis | 111,117 |
| Paracoccidioides brasiliensis | Y → M | PKA G protein, Ras cAMP, GPA: putative Rho1, SEP1, FLB1: signal, polarity, shape PKC1: putative Ca+2/Calmodulin: morphogenetic differentiation Y → M | 112,123,124 | |
| Histoplasma capsulatum | Y → M | Ca+2/Calmodulin: differentiation Y → M | 125 | |
PKC — Protein Kinase C; cAMP — cyclic adenosine 5′ monophosphate; MAPK — mitogen activated protein kinase; PKA: cyclic AMP-dependent protein kinase; Y: yeast; M: mycelium.
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