Antibiotic treatment of infective endocarditis due to oral streptococci and group D streptococcia
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aSee text for other streptococcal species.
bPreferred in patients >65 years or with impaired renal function.
c6-week therapy in PVE.
dOr ampicillin, same dosages as amoxicillin.
ePreferred for outpatient therapy.
fPaediatric doses should not exceed adult doses.
gOnly if non complicated native valve IE.
hRenal function and serum gentamicin concentrations should be monitored once a week. When given in a single daily dose, pre-dose (trough) concentrations should be <1 mg/L and post-dose (peak; 1 h after injection) serum concentrations should be ∼10–12 mg/L.112
iSerum vancomycin concentrations should achieve 10–15 mg/L at pre-dose (trough) level and 30–45 mg/L at post-dose level (peak; 1 h after infusion is completed).
Antibiotic treatment of infective endocarditis due to oral streptococci and group D streptococcia
|
|
aSee text for other streptococcal species.
bPreferred in patients >65 years or with impaired renal function.
c6-week therapy in PVE.
dOr ampicillin, same dosages as amoxicillin.
ePreferred for outpatient therapy.
fPaediatric doses should not exceed adult doses.
gOnly if non complicated native valve IE.
hRenal function and serum gentamicin concentrations should be monitored once a week. When given in a single daily dose, pre-dose (trough) concentrations should be <1 mg/L and post-dose (peak; 1 h after injection) serum concentrations should be ∼10–12 mg/L.112
iSerum vancomycin concentrations should achieve 10–15 mg/L at pre-dose (trough) level and 30–45 mg/L at post-dose level (peak; 1 h after infusion is completed).
