Clinical and demographics characteristics of the APA patients recruited in the 13 meta-analyzed studies
| . | KCNJ5 Mutated (n = 725) . | KCNJ5 Wild Type (n = 911) . |
|---|---|---|
| Age (years) | 45 ± 3 | 52 ± 5 |
| Females/males (%) | 69/31 | 44/56 |
| PAC (ng/dl) | 41.8 ±8.4 | 32.8 ± 7.4 |
| PRA (ng/ml/hr) ARR (ng/dl)/ (ng/ml/hr) | 0.29 ± 0.09 | 0.42 ± 0.20 |
| ARR (ng/dl)/ (ng/ml/hr) | 157 ± 55 | 85 ± 55 |
| Serum K+ (mEq/L) | 3.04 ± 0.30 | 3.17 ± 0.20 |
| Systolic BP (mm Hg) | 151 ± 10 | 156 ± 9 |
| Diastolic BP (mm Hg) | 93 ± 5 | 92 ± 9 |
| Tumor size (mm) | 16.3 ± 6.1 | 14.9 ±7.4 |
| . | KCNJ5 Mutated (n = 725) . | KCNJ5 Wild Type (n = 911) . |
|---|---|---|
| Age (years) | 45 ± 3 | 52 ± 5 |
| Females/males (%) | 69/31 | 44/56 |
| PAC (ng/dl) | 41.8 ±8.4 | 32.8 ± 7.4 |
| PRA (ng/ml/hr) ARR (ng/dl)/ (ng/ml/hr) | 0.29 ± 0.09 | 0.42 ± 0.20 |
| ARR (ng/dl)/ (ng/ml/hr) | 157 ± 55 | 85 ± 55 |
| Serum K+ (mEq/L) | 3.04 ± 0.30 | 3.17 ± 0.20 |
| Systolic BP (mm Hg) | 151 ± 10 | 156 ± 9 |
| Diastolic BP (mm Hg) | 93 ± 5 | 92 ± 9 |
| Tumor size (mm) | 16.3 ± 6.1 | 14.9 ±7.4 |
For significant differences please refer to the forest plots. All items are mean ± standard deviation.
Abbreviations: ARR, aldo renin ratio; BP, blood pressure. PAC, plasma aldosterone; PRA, plasma renin activity; Serum K+, serum potassium.
Clinical and demographics characteristics of the APA patients recruited in the 13 meta-analyzed studies
| . | KCNJ5 Mutated (n = 725) . | KCNJ5 Wild Type (n = 911) . |
|---|---|---|
| Age (years) | 45 ± 3 | 52 ± 5 |
| Females/males (%) | 69/31 | 44/56 |
| PAC (ng/dl) | 41.8 ±8.4 | 32.8 ± 7.4 |
| PRA (ng/ml/hr) ARR (ng/dl)/ (ng/ml/hr) | 0.29 ± 0.09 | 0.42 ± 0.20 |
| ARR (ng/dl)/ (ng/ml/hr) | 157 ± 55 | 85 ± 55 |
| Serum K+ (mEq/L) | 3.04 ± 0.30 | 3.17 ± 0.20 |
| Systolic BP (mm Hg) | 151 ± 10 | 156 ± 9 |
| Diastolic BP (mm Hg) | 93 ± 5 | 92 ± 9 |
| Tumor size (mm) | 16.3 ± 6.1 | 14.9 ±7.4 |
| . | KCNJ5 Mutated (n = 725) . | KCNJ5 Wild Type (n = 911) . |
|---|---|---|
| Age (years) | 45 ± 3 | 52 ± 5 |
| Females/males (%) | 69/31 | 44/56 |
| PAC (ng/dl) | 41.8 ±8.4 | 32.8 ± 7.4 |
| PRA (ng/ml/hr) ARR (ng/dl)/ (ng/ml/hr) | 0.29 ± 0.09 | 0.42 ± 0.20 |
| ARR (ng/dl)/ (ng/ml/hr) | 157 ± 55 | 85 ± 55 |
| Serum K+ (mEq/L) | 3.04 ± 0.30 | 3.17 ± 0.20 |
| Systolic BP (mm Hg) | 151 ± 10 | 156 ± 9 |
| Diastolic BP (mm Hg) | 93 ± 5 | 92 ± 9 |
| Tumor size (mm) | 16.3 ± 6.1 | 14.9 ±7.4 |
For significant differences please refer to the forest plots. All items are mean ± standard deviation.
Abbreviations: ARR, aldo renin ratio; BP, blood pressure. PAC, plasma aldosterone; PRA, plasma renin activity; Serum K+, serum potassium.
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