Table 1. Open in new tab Anti-...

Table 1.

Anti-Orthopoxvirus IgG and IgM Results for Serum Samples from the Patient and 4 Contacts^a

Person	Smallpox vaccination	IgM Value^b	IgM Interpretation	IgG Value^b	IgG interpretation
Patient	Unlikely^c	0.091	Positive	0.183	Positive
Patient’s partner (household contact)	Yes	−0.024	Negative	0.426	Positive
Patient’s older child (household contact)	No	0.032	Equivocal^d	−0.201	Negative
Patient’s younger child (household contact)	No	−0.020	Negative	−0.194	Negative
Patient’s friend (social contact)	Yes	−0.034	Negative	0.483	Positive

Person	Smallpox vaccination	IgM Value^b	IgM Interpretation	IgG Value^b	IgG interpretation
Patient	Unlikely^c	0.091	Positive	0.183	Positive
Patient’s partner (household contact)	Yes	−0.024	Negative	0.426	Positive
Patient’s older child (household contact)	No	0.032	Equivocal^d	−0.201	Negative
Patient’s younger child (household contact)	No	−0.020	Negative	−0.194	Negative
Patient’s friend (social contact)	Yes	−0.034	Negative	0.483	Positive

Abbreviation: Ig, immunoglobulin.

^aSerology was performed using enzyme-linked immunosorbent assays.

^bSerum optical density (OD) cutoff values (OD value − 3 standard deviations of negative control) at 1:50 and 1:100 dilutions were considered positive for IgM and IgG, respectively.

^cThe patient did not recall being vaccinated and did not have a vaccination scar.

^dThe sample from the patient’s older child was positive for anti-Orthopoxvirus IgM, but because this value was low and the corresponding anti-Orthopoxvirus IgG result was negative, the result was interpreted as equivocal.

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