Cohort Characteristics and Behavioral Risk Factors for Primary Human Herpesvirus Infection
| Characteristics of Primary Childrena . | Maternal HIV-1 Status . | ||
|---|---|---|---|
| Negative . | Positive . | Overall . | |
| Primary children | |||
| Evaluated, no. | 15 | 17 | 32 |
| Male sex | 6 (40) | 10 (59) | 16 (50) |
| Oropharyngeal samples collected weekly, no. | 57 (32–75) | 58 (4–117) | 58 (4–117) |
| Secondary children | |||
| Evaluated, no. | 22 | 27 | 49 |
| Age, y | 3.9 (1.6–6.3) | 3.6 (0.3–6.5) | 3.8 (0.3–6.5) |
| HIV-1 infected | 0 (0) | 4 (15) | 4 (8) |
| HIV-1 status unknown | 0 (0) | 7 (26) | 7 (14) |
| No. per family | |||
| 1 | 11 (73) | 10 (59) | 21 (66) |
| 2 | 1 (7) | 4 (24) | 5 (16) |
| 3 | 3 (20) | 3 (18) | 6 (19) |
| Behavioral exposureb | |||
| Breastfeeding during study | |||
| None | 0 (0) | 4 (24) | 4 (12) |
| Weaned during study | 3 (20) | 11 (65) | 14 (44) |
| Breastfed for entire study | 12 (80) | 2 (12) | 14 (44) |
| Breastfeeding duration,c wks | 45 (25–78) | 14 (1–31) | 21 (1–78) |
| Visits with saliva-sharing behavior,d % | 62 (0–100) | 21 (0–87) | 50 (0–100) |
| Characteristics of Primary Childrena . | Maternal HIV-1 Status . | ||
|---|---|---|---|
| Negative . | Positive . | Overall . | |
| Primary children | |||
| Evaluated, no. | 15 | 17 | 32 |
| Male sex | 6 (40) | 10 (59) | 16 (50) |
| Oropharyngeal samples collected weekly, no. | 57 (32–75) | 58 (4–117) | 58 (4–117) |
| Secondary children | |||
| Evaluated, no. | 22 | 27 | 49 |
| Age, y | 3.9 (1.6–6.3) | 3.6 (0.3–6.5) | 3.8 (0.3–6.5) |
| HIV-1 infected | 0 (0) | 4 (15) | 4 (8) |
| HIV-1 status unknown | 0 (0) | 7 (26) | 7 (14) |
| No. per family | |||
| 1 | 11 (73) | 10 (59) | 21 (66) |
| 2 | 1 (7) | 4 (24) | 5 (16) |
| 3 | 3 (20) | 3 (18) | 6 (19) |
| Behavioral exposureb | |||
| Breastfeeding during study | |||
| None | 0 (0) | 4 (24) | 4 (12) |
| Weaned during study | 3 (20) | 11 (65) | 14 (44) |
| Breastfed for entire study | 12 (80) | 2 (12) | 14 (44) |
| Breastfeeding duration,c wks | 45 (25–78) | 14 (1–31) | 21 (1–78) |
| Visits with saliva-sharing behavior,d % | 62 (0–100) | 21 (0–87) | 50 (0–100) |
Data are no. (%) of subjects or median value (range), unless otherwise indicated.
Abbreviation: HIV-1, human immunodeficiency virus type 1.
a No primary children acquired HIV-1 during study follow-up.
b Data regarding breastfeeding and saliva-sharing behaviors were captured each week, using a standardized questionnaire. Saliva-sharing behaviors between mothers and primary children represent a composite of any of the following behaviors reported during a study week: premastication of food given to primary child, kissing primary child on the mouth, sharing drinking or eating utensils with primary child, and rubbing saliva into a bite or wound.
c Among mothers who weaned during study.
d Percentage of visits with each behavior, calculated per household.
Cohort Characteristics and Behavioral Risk Factors for Primary Human Herpesvirus Infection
| Characteristics of Primary Childrena . | Maternal HIV-1 Status . | ||
|---|---|---|---|
| Negative . | Positive . | Overall . | |
| Primary children | |||
| Evaluated, no. | 15 | 17 | 32 |
| Male sex | 6 (40) | 10 (59) | 16 (50) |
| Oropharyngeal samples collected weekly, no. | 57 (32–75) | 58 (4–117) | 58 (4–117) |
| Secondary children | |||
| Evaluated, no. | 22 | 27 | 49 |
| Age, y | 3.9 (1.6–6.3) | 3.6 (0.3–6.5) | 3.8 (0.3–6.5) |
| HIV-1 infected | 0 (0) | 4 (15) | 4 (8) |
| HIV-1 status unknown | 0 (0) | 7 (26) | 7 (14) |
| No. per family | |||
| 1 | 11 (73) | 10 (59) | 21 (66) |
| 2 | 1 (7) | 4 (24) | 5 (16) |
| 3 | 3 (20) | 3 (18) | 6 (19) |
| Behavioral exposureb | |||
| Breastfeeding during study | |||
| None | 0 (0) | 4 (24) | 4 (12) |
| Weaned during study | 3 (20) | 11 (65) | 14 (44) |
| Breastfed for entire study | 12 (80) | 2 (12) | 14 (44) |
| Breastfeeding duration,c wks | 45 (25–78) | 14 (1–31) | 21 (1–78) |
| Visits with saliva-sharing behavior,d % | 62 (0–100) | 21 (0–87) | 50 (0–100) |
| Characteristics of Primary Childrena . | Maternal HIV-1 Status . | ||
|---|---|---|---|
| Negative . | Positive . | Overall . | |
| Primary children | |||
| Evaluated, no. | 15 | 17 | 32 |
| Male sex | 6 (40) | 10 (59) | 16 (50) |
| Oropharyngeal samples collected weekly, no. | 57 (32–75) | 58 (4–117) | 58 (4–117) |
| Secondary children | |||
| Evaluated, no. | 22 | 27 | 49 |
| Age, y | 3.9 (1.6–6.3) | 3.6 (0.3–6.5) | 3.8 (0.3–6.5) |
| HIV-1 infected | 0 (0) | 4 (15) | 4 (8) |
| HIV-1 status unknown | 0 (0) | 7 (26) | 7 (14) |
| No. per family | |||
| 1 | 11 (73) | 10 (59) | 21 (66) |
| 2 | 1 (7) | 4 (24) | 5 (16) |
| 3 | 3 (20) | 3 (18) | 6 (19) |
| Behavioral exposureb | |||
| Breastfeeding during study | |||
| None | 0 (0) | 4 (24) | 4 (12) |
| Weaned during study | 3 (20) | 11 (65) | 14 (44) |
| Breastfed for entire study | 12 (80) | 2 (12) | 14 (44) |
| Breastfeeding duration,c wks | 45 (25–78) | 14 (1–31) | 21 (1–78) |
| Visits with saliva-sharing behavior,d % | 62 (0–100) | 21 (0–87) | 50 (0–100) |
Data are no. (%) of subjects or median value (range), unless otherwise indicated.
Abbreviation: HIV-1, human immunodeficiency virus type 1.
a No primary children acquired HIV-1 during study follow-up.
b Data regarding breastfeeding and saliva-sharing behaviors were captured each week, using a standardized questionnaire. Saliva-sharing behaviors between mothers and primary children represent a composite of any of the following behaviors reported during a study week: premastication of food given to primary child, kissing primary child on the mouth, sharing drinking or eating utensils with primary child, and rubbing saliva into a bite or wound.
c Among mothers who weaned during study.
d Percentage of visits with each behavior, calculated per household.
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