TABLE 5
Open in new tab

Summary of Significant Biochemical and Pathological Findings at Day 91 in the Mouse Duodenum

EndpointSDD, mg/l
0.341460170520
Tissue Cr——↑↑↑↑
GSH/GSSG——↓↓↓↓
Vacuolization———↑↑↑
Atrophy/apoptosis————↑↑
Crypt cell proliferation————↑↑
EndpointSDD, mg/l
0.341460170520
Tissue Cr——↑↑↑↑
GSH/GSSG——↓↓↓↓
Vacuolization———↑↑↑
Atrophy/apoptosis————↑↑
Crypt cell proliferation————↑↑
TABLE 5
Open in new tab

Summary of Significant Biochemical and Pathological Findings at Day 91 in the Mouse Duodenum

EndpointSDD, mg/l
0.341460170520
Tissue Cr——↑↑↑↑
GSH/GSSG——↓↓↓↓
Vacuolization———↑↑↑
Atrophy/apoptosis————↑↑
Crypt cell proliferation————↑↑
EndpointSDD, mg/l
0.341460170520
Tissue Cr——↑↑↑↑
GSH/GSSG——↓↓↓↓
Vacuolization———↑↑↑
Atrophy/apoptosis————↑↑
Crypt cell proliferation————↑↑
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