Prevalence of Signs, Symptoms, and Diagnoses in Ebola Virus Disease Survivors Enrolled in the Médecins Sans Frontières Follow-up Program in Freetown, Sierra Leone
| Signs, Symptoms, and Diagnoses . | All (N = 166) . | Adults (≥16 y) (n = 128) . | Children (≤15 y) (n = 38) . | P Value . |
|---|---|---|---|---|
| Arthralgia | 129 (77.7) | 109 (85.1) | 20 (52.6) | ≤.001 |
| Fatigue | 116 (69.8) | 94 (73.4) | 22 (57.8) | .067 |
| Abdominal pain | 90 (54.2) | 72 (56.2) | 18 (47.3) | .335 |
| Headache | 87 (52.4) | 66 (51.5) | 21 (55.3) | .688 |
| Anemia | 83 (50) | 55 (42.9) | 28 (73.7) | .001 |
| Skin rash or infection/itching/desquamation | 81 (48.8) | 54 (41.2) | 27 (71.0) | .002 |
| Back pain | 54 (32.5) | 46 (35.9) | 8 (21.0) | .085 |
| Alopecia (diffuse) | 53 (31.9) | 43 (33.5) | 10 (26.3) | .398 |
| Respiratory tract infection + otitis | 45 (27.1) | 29 (22.6) | 16 (42.1) | .018 |
| Anorexia | 43 (25.9) | 36 (28.1) | 7 (18.4) | .294 |
| Genital/urinary tract infection/STI | 38 (22.8) | 36 (28.1) | 2 (5.3) | .002 |
| Insomnia | 30 (18.0) | 29 (22.6) | 1 (2.6) | .003 |
| Gastritis/ulcer/GERD | 27 (16.2) | 26 (20.3) | 1 (2.6) | .01 |
| Malaria | 23 (13.8) | 14 (10.9) | 9 (23.7) | .046 |
| Moderate acute malnutrition | 19 (11.4) | 7 (5.4) | 12 (31.6) | ≤.001 |
| Cardiopathy/valvulopathy/tachycardia | 19 (11.4) | 17 (13.2) | 2 (5.3) | .248 |
| Amenorrheaa | 7 (10.1) | 7 (10.7) | 0 | .353 |
| Arterial hypertension | 12 (7.2) | 12 (9.3) | 0 | .07 |
| Diarrhea/gastroenteritis | 9 (5.4) | 7 (5.4) | 2 (5.3) | 1 |
| Tinnitus/hearing loss | 5 (3.0) | 4 (3.1) | 1 (2.6) | 1 |
| Severe acute malnutrition | 2 (1.2) | 0 | 2 (5.3) | .051 |
| Myocarditis (clinically suspect) | 2 (1.2) | 2 (1.5) | 0 | 1 |
| Any ocular complication | 94 (56.6) | 74 (57.8) | 20 (52.6) | .61 |
| Uveitis | 58 (34.9) | 50 (39.0) | 8 (32.1) | .03 |
| Signs, Symptoms, and Diagnoses . | All (N = 166) . | Adults (≥16 y) (n = 128) . | Children (≤15 y) (n = 38) . | P Value . |
|---|---|---|---|---|
| Arthralgia | 129 (77.7) | 109 (85.1) | 20 (52.6) | ≤.001 |
| Fatigue | 116 (69.8) | 94 (73.4) | 22 (57.8) | .067 |
| Abdominal pain | 90 (54.2) | 72 (56.2) | 18 (47.3) | .335 |
| Headache | 87 (52.4) | 66 (51.5) | 21 (55.3) | .688 |
| Anemia | 83 (50) | 55 (42.9) | 28 (73.7) | .001 |
| Skin rash or infection/itching/desquamation | 81 (48.8) | 54 (41.2) | 27 (71.0) | .002 |
| Back pain | 54 (32.5) | 46 (35.9) | 8 (21.0) | .085 |
| Alopecia (diffuse) | 53 (31.9) | 43 (33.5) | 10 (26.3) | .398 |
| Respiratory tract infection + otitis | 45 (27.1) | 29 (22.6) | 16 (42.1) | .018 |
| Anorexia | 43 (25.9) | 36 (28.1) | 7 (18.4) | .294 |
| Genital/urinary tract infection/STI | 38 (22.8) | 36 (28.1) | 2 (5.3) | .002 |
| Insomnia | 30 (18.0) | 29 (22.6) | 1 (2.6) | .003 |
| Gastritis/ulcer/GERD | 27 (16.2) | 26 (20.3) | 1 (2.6) | .01 |
| Malaria | 23 (13.8) | 14 (10.9) | 9 (23.7) | .046 |
| Moderate acute malnutrition | 19 (11.4) | 7 (5.4) | 12 (31.6) | ≤.001 |
| Cardiopathy/valvulopathy/tachycardia | 19 (11.4) | 17 (13.2) | 2 (5.3) | .248 |
| Amenorrheaa | 7 (10.1) | 7 (10.7) | 0 | .353 |
| Arterial hypertension | 12 (7.2) | 12 (9.3) | 0 | .07 |
| Diarrhea/gastroenteritis | 9 (5.4) | 7 (5.4) | 2 (5.3) | 1 |
| Tinnitus/hearing loss | 5 (3.0) | 4 (3.1) | 1 (2.6) | 1 |
| Severe acute malnutrition | 2 (1.2) | 0 | 2 (5.3) | .051 |
| Myocarditis (clinically suspect) | 2 (1.2) | 2 (1.5) | 0 | 1 |
| Any ocular complication | 94 (56.6) | 74 (57.8) | 20 (52.6) | .61 |
| Uveitis | 58 (34.9) | 50 (39.0) | 8 (32.1) | .03 |
Data are presented as No. (%).
Abbreviations: GERD, gastroesophageal reflux disease; STI, sexually transmitted infection.
a Considered only for women >10 years of age: n = 69 for all (n = 65 for adults, n = 4 for children aged 10–15 years).
Prevalence of Signs, Symptoms, and Diagnoses in Ebola Virus Disease Survivors Enrolled in the Médecins Sans Frontières Follow-up Program in Freetown, Sierra Leone
| Signs, Symptoms, and Diagnoses . | All (N = 166) . | Adults (≥16 y) (n = 128) . | Children (≤15 y) (n = 38) . | P Value . |
|---|---|---|---|---|
| Arthralgia | 129 (77.7) | 109 (85.1) | 20 (52.6) | ≤.001 |
| Fatigue | 116 (69.8) | 94 (73.4) | 22 (57.8) | .067 |
| Abdominal pain | 90 (54.2) | 72 (56.2) | 18 (47.3) | .335 |
| Headache | 87 (52.4) | 66 (51.5) | 21 (55.3) | .688 |
| Anemia | 83 (50) | 55 (42.9) | 28 (73.7) | .001 |
| Skin rash or infection/itching/desquamation | 81 (48.8) | 54 (41.2) | 27 (71.0) | .002 |
| Back pain | 54 (32.5) | 46 (35.9) | 8 (21.0) | .085 |
| Alopecia (diffuse) | 53 (31.9) | 43 (33.5) | 10 (26.3) | .398 |
| Respiratory tract infection + otitis | 45 (27.1) | 29 (22.6) | 16 (42.1) | .018 |
| Anorexia | 43 (25.9) | 36 (28.1) | 7 (18.4) | .294 |
| Genital/urinary tract infection/STI | 38 (22.8) | 36 (28.1) | 2 (5.3) | .002 |
| Insomnia | 30 (18.0) | 29 (22.6) | 1 (2.6) | .003 |
| Gastritis/ulcer/GERD | 27 (16.2) | 26 (20.3) | 1 (2.6) | .01 |
| Malaria | 23 (13.8) | 14 (10.9) | 9 (23.7) | .046 |
| Moderate acute malnutrition | 19 (11.4) | 7 (5.4) | 12 (31.6) | ≤.001 |
| Cardiopathy/valvulopathy/tachycardia | 19 (11.4) | 17 (13.2) | 2 (5.3) | .248 |
| Amenorrheaa | 7 (10.1) | 7 (10.7) | 0 | .353 |
| Arterial hypertension | 12 (7.2) | 12 (9.3) | 0 | .07 |
| Diarrhea/gastroenteritis | 9 (5.4) | 7 (5.4) | 2 (5.3) | 1 |
| Tinnitus/hearing loss | 5 (3.0) | 4 (3.1) | 1 (2.6) | 1 |
| Severe acute malnutrition | 2 (1.2) | 0 | 2 (5.3) | .051 |
| Myocarditis (clinically suspect) | 2 (1.2) | 2 (1.5) | 0 | 1 |
| Any ocular complication | 94 (56.6) | 74 (57.8) | 20 (52.6) | .61 |
| Uveitis | 58 (34.9) | 50 (39.0) | 8 (32.1) | .03 |
| Signs, Symptoms, and Diagnoses . | All (N = 166) . | Adults (≥16 y) (n = 128) . | Children (≤15 y) (n = 38) . | P Value . |
|---|---|---|---|---|
| Arthralgia | 129 (77.7) | 109 (85.1) | 20 (52.6) | ≤.001 |
| Fatigue | 116 (69.8) | 94 (73.4) | 22 (57.8) | .067 |
| Abdominal pain | 90 (54.2) | 72 (56.2) | 18 (47.3) | .335 |
| Headache | 87 (52.4) | 66 (51.5) | 21 (55.3) | .688 |
| Anemia | 83 (50) | 55 (42.9) | 28 (73.7) | .001 |
| Skin rash or infection/itching/desquamation | 81 (48.8) | 54 (41.2) | 27 (71.0) | .002 |
| Back pain | 54 (32.5) | 46 (35.9) | 8 (21.0) | .085 |
| Alopecia (diffuse) | 53 (31.9) | 43 (33.5) | 10 (26.3) | .398 |
| Respiratory tract infection + otitis | 45 (27.1) | 29 (22.6) | 16 (42.1) | .018 |
| Anorexia | 43 (25.9) | 36 (28.1) | 7 (18.4) | .294 |
| Genital/urinary tract infection/STI | 38 (22.8) | 36 (28.1) | 2 (5.3) | .002 |
| Insomnia | 30 (18.0) | 29 (22.6) | 1 (2.6) | .003 |
| Gastritis/ulcer/GERD | 27 (16.2) | 26 (20.3) | 1 (2.6) | .01 |
| Malaria | 23 (13.8) | 14 (10.9) | 9 (23.7) | .046 |
| Moderate acute malnutrition | 19 (11.4) | 7 (5.4) | 12 (31.6) | ≤.001 |
| Cardiopathy/valvulopathy/tachycardia | 19 (11.4) | 17 (13.2) | 2 (5.3) | .248 |
| Amenorrheaa | 7 (10.1) | 7 (10.7) | 0 | .353 |
| Arterial hypertension | 12 (7.2) | 12 (9.3) | 0 | .07 |
| Diarrhea/gastroenteritis | 9 (5.4) | 7 (5.4) | 2 (5.3) | 1 |
| Tinnitus/hearing loss | 5 (3.0) | 4 (3.1) | 1 (2.6) | 1 |
| Severe acute malnutrition | 2 (1.2) | 0 | 2 (5.3) | .051 |
| Myocarditis (clinically suspect) | 2 (1.2) | 2 (1.5) | 0 | 1 |
| Any ocular complication | 94 (56.6) | 74 (57.8) | 20 (52.6) | .61 |
| Uveitis | 58 (34.9) | 50 (39.0) | 8 (32.1) | .03 |
Data are presented as No. (%).
Abbreviations: GERD, gastroesophageal reflux disease; STI, sexually transmitted infection.
a Considered only for women >10 years of age: n = 69 for all (n = 65 for adults, n = 4 for children aged 10–15 years).
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