Differential expression correlates with changes in nuclear matrix attachment
| Chromosomes . | Genes expressed in AoAF cells . | AoAF expressed genes silenced in HeLa . | Subset containing AoAF MARs . | Subset containing HeLa MARs . |
|---|---|---|---|---|
| 14 | 64 | 28 | 0 | 15 |
| 15 | 72 | 34 | 0 | 12 |
| 16 | 112 | 41 | 1 | 11 |
| 17 | 147 | 47 | 1 | 8 |
| 18 | 20 | 10 | 3 | 7 |
| Chromosomes . | Genes expressed in AoAF cells . | AoAF expressed genes silenced in HeLa . | Subset containing AoAF MARs . | Subset containing HeLa MARs . |
|---|---|---|---|---|
| 14 | 64 | 28 | 0 | 15 |
| 15 | 72 | 34 | 0 | 12 |
| 16 | 112 | 41 | 1 | 11 |
| 17 | 147 | 47 | 1 | 8 |
| 18 | 20 | 10 | 3 | 7 |
Genes represented on both the expression and aCGH arrays were analyzed for differences between cell types. Many genes that are expressed in AoAF cells are bound to the nuclear matrix and silent in HeLa cells (i.e. subset containing HeLa MARs), while relatively few are nuclear matrix bound in the AoAF cells (i.e. subset containing AoAF MARs).
Differential expression correlates with changes in nuclear matrix attachment
| Chromosomes . | Genes expressed in AoAF cells . | AoAF expressed genes silenced in HeLa . | Subset containing AoAF MARs . | Subset containing HeLa MARs . |
|---|---|---|---|---|
| 14 | 64 | 28 | 0 | 15 |
| 15 | 72 | 34 | 0 | 12 |
| 16 | 112 | 41 | 1 | 11 |
| 17 | 147 | 47 | 1 | 8 |
| 18 | 20 | 10 | 3 | 7 |
| Chromosomes . | Genes expressed in AoAF cells . | AoAF expressed genes silenced in HeLa . | Subset containing AoAF MARs . | Subset containing HeLa MARs . |
|---|---|---|---|---|
| 14 | 64 | 28 | 0 | 15 |
| 15 | 72 | 34 | 0 | 12 |
| 16 | 112 | 41 | 1 | 11 |
| 17 | 147 | 47 | 1 | 8 |
| 18 | 20 | 10 | 3 | 7 |
Genes represented on both the expression and aCGH arrays were analyzed for differences between cell types. Many genes that are expressed in AoAF cells are bound to the nuclear matrix and silent in HeLa cells (i.e. subset containing HeLa MARs), while relatively few are nuclear matrix bound in the AoAF cells (i.e. subset containing AoAF MARs).
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