Table 1. Open in new tab AoAF cell...

Table 1.

AoAF cell nuclear matrix attachment correlates with silencing

Chromosomes	All genes	Expressed genes	Genes overlapped by MARs	Average no. of MARs per gene	Expressed genes overlapped by MARs
14	433	64	76	4	2
15	534	72	60	4	1
16	758	112	53	5	4
17	1058	147	67	3	1
18	162	20	44	3	4

Chromosomes	All genes	Expressed genes	Genes overlapped by MARs	Average no. of MARs per gene	Expressed genes overlapped by MARs
14	433	64	76	4	2
15	534	72	60	4	1
16	758	112	53	5	4
17	1058	147	67	3	1
18	162	20	44	3	4

For each gene that was represented by probes on both the expression (Illumina) and aCGH (NimbleGen) microarrays, the correlation between expression and matrix attachment was measured. Of the subset of genes that contain MARs, they contain an average of four MARs per gene. The observed correlation between matrix attachment and gene silencing is statistically significant for all chromosomes (P < 0.001).

This Feature Is Available To Subscribers Only