Table 1.

Baseline Clinical Characteristics

Total GroupGH/GnRHaGHP Value
No.1106743
Boys/girls51/5925/4226/17.018
Gestational age, wk37.4 (3.3)37.4 (3.6)37.5 (3.0).886
Birth weight SDS−2.0 (1.0)a−2.0 (0.9)a−2.0 (1.0)a.888
Birth length SDS−2.7 (1.3)a−2.8 (1.3)a−2.6 (1.2)a.513
Target height SDS−0.7 (0.7)a−0.7 (0.7)a−0.7 (0.7)a.849
Age, y11.4 (1.5)11.6 (1.2)11.0 (1.8).065
Height SDS−2.9 (0.6)a−2.9 (0.7)a−2.9 (0.6)a.591
Body mass index SDS−1.0 (1.0)−0.9 (1.0)−1.2 (1.0).202
IGF-I SDS−1.17 (1.2)−1.08 (1.1)−1.30 (1.5).374
Prepubertal/pubertal52/5819/4833/10<.001
Pubertal stage (14)
    Tanner 1521933
    Tanner 241365
    Tanner 317125
Fasting glucose, mmol/L5.0 (0.5)5.0 (0.5)4.9 (0.5).605
Fasting insulin, mU/L5.3 (4.8)6.3 (5.5)3.8 (3.0).406
HOMA-IR1.2 (1.2)1.5 (1.4)0.9 (0.8).471
Total GroupGH/GnRHaGHP Value
No.1106743
Boys/girls51/5925/4226/17.018
Gestational age, wk37.4 (3.3)37.4 (3.6)37.5 (3.0).886
Birth weight SDS−2.0 (1.0)a−2.0 (0.9)a−2.0 (1.0)a.888
Birth length SDS−2.7 (1.3)a−2.8 (1.3)a−2.6 (1.2)a.513
Target height SDS−0.7 (0.7)a−0.7 (0.7)a−0.7 (0.7)a.849
Age, y11.4 (1.5)11.6 (1.2)11.0 (1.8).065
Height SDS−2.9 (0.6)a−2.9 (0.7)a−2.9 (0.6)a.591
Body mass index SDS−1.0 (1.0)−0.9 (1.0)−1.2 (1.0).202
IGF-I SDS−1.17 (1.2)−1.08 (1.1)−1.30 (1.5).374
Prepubertal/pubertal52/5819/4833/10<.001
Pubertal stage (14)
    Tanner 1521933
    Tanner 241365
    Tanner 317125
Fasting glucose, mmol/L5.0 (0.5)5.0 (0.5)4.9 (0.5).605
Fasting insulin, mU/L5.3 (4.8)6.3 (5.5)3.8 (3.0).406
HOMA-IR1.2 (1.2)1.5 (1.4)0.9 (0.8).471

Data are expressed as mean (SDS), unless written otherwise. Fasting insulin and HOMA-IR were square root–transformed before analyses and adjusted for Tanner stage at baseline. Bold text indicates a significant P-value (<.05)

a

Variables in SDS compared with 0 SDS, P < .01.

Table 1.

Baseline Clinical Characteristics

Total GroupGH/GnRHaGHP Value
No.1106743
Boys/girls51/5925/4226/17.018
Gestational age, wk37.4 (3.3)37.4 (3.6)37.5 (3.0).886
Birth weight SDS−2.0 (1.0)a−2.0 (0.9)a−2.0 (1.0)a.888
Birth length SDS−2.7 (1.3)a−2.8 (1.3)a−2.6 (1.2)a.513
Target height SDS−0.7 (0.7)a−0.7 (0.7)a−0.7 (0.7)a.849
Age, y11.4 (1.5)11.6 (1.2)11.0 (1.8).065
Height SDS−2.9 (0.6)a−2.9 (0.7)a−2.9 (0.6)a.591
Body mass index SDS−1.0 (1.0)−0.9 (1.0)−1.2 (1.0).202
IGF-I SDS−1.17 (1.2)−1.08 (1.1)−1.30 (1.5).374
Prepubertal/pubertal52/5819/4833/10<.001
Pubertal stage (14)
    Tanner 1521933
    Tanner 241365
    Tanner 317125
Fasting glucose, mmol/L5.0 (0.5)5.0 (0.5)4.9 (0.5).605
Fasting insulin, mU/L5.3 (4.8)6.3 (5.5)3.8 (3.0).406
HOMA-IR1.2 (1.2)1.5 (1.4)0.9 (0.8).471
Total GroupGH/GnRHaGHP Value
No.1106743
Boys/girls51/5925/4226/17.018
Gestational age, wk37.4 (3.3)37.4 (3.6)37.5 (3.0).886
Birth weight SDS−2.0 (1.0)a−2.0 (0.9)a−2.0 (1.0)a.888
Birth length SDS−2.7 (1.3)a−2.8 (1.3)a−2.6 (1.2)a.513
Target height SDS−0.7 (0.7)a−0.7 (0.7)a−0.7 (0.7)a.849
Age, y11.4 (1.5)11.6 (1.2)11.0 (1.8).065
Height SDS−2.9 (0.6)a−2.9 (0.7)a−2.9 (0.6)a.591
Body mass index SDS−1.0 (1.0)−0.9 (1.0)−1.2 (1.0).202
IGF-I SDS−1.17 (1.2)−1.08 (1.1)−1.30 (1.5).374
Prepubertal/pubertal52/5819/4833/10<.001
Pubertal stage (14)
    Tanner 1521933
    Tanner 241365
    Tanner 317125
Fasting glucose, mmol/L5.0 (0.5)5.0 (0.5)4.9 (0.5).605
Fasting insulin, mU/L5.3 (4.8)6.3 (5.5)3.8 (3.0).406
HOMA-IR1.2 (1.2)1.5 (1.4)0.9 (0.8).471

Data are expressed as mean (SDS), unless written otherwise. Fasting insulin and HOMA-IR were square root–transformed before analyses and adjusted for Tanner stage at baseline. Bold text indicates a significant P-value (<.05)

a

Variables in SDS compared with 0 SDS, P < .01.

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