. | Total Group . | GH/GnRHa . | GH . | P Value . |
---|---|---|---|---|
No. | 110 | 67 | 43 | |
Boys/girls | 51/59 | 25/42 | 26/17 | .018 |
Gestational age, wk | 37.4 (3.3) | 37.4 (3.6) | 37.5 (3.0) | .886 |
Birth weight SDS | −2.0 (1.0)a | −2.0 (0.9)a | −2.0 (1.0)a | .888 |
Birth length SDS | −2.7 (1.3)a | −2.8 (1.3)a | −2.6 (1.2)a | .513 |
Target height SDS | −0.7 (0.7)a | −0.7 (0.7)a | −0.7 (0.7)a | .849 |
Age, y | 11.4 (1.5) | 11.6 (1.2) | 11.0 (1.8) | .065 |
Height SDS | −2.9 (0.6)a | −2.9 (0.7)a | −2.9 (0.6)a | .591 |
Body mass index SDS | −1.0 (1.0) | −0.9 (1.0) | −1.2 (1.0) | .202 |
IGF-I SDS | −1.17 (1.2) | −1.08 (1.1) | −1.30 (1.5) | .374 |
Prepubertal/pubertal | 52/58 | 19/48 | 33/10 | <.001 |
Pubertal stage (14) | ||||
Tanner 1 | 52 | 19 | 33 | |
Tanner 2 | 41 | 36 | 5 | |
Tanner 3 | 17 | 12 | 5 | |
Fasting glucose, mmol/L | 5.0 (0.5) | 5.0 (0.5) | 4.9 (0.5) | .605 |
Fasting insulin, mU/L | 5.3 (4.8) | 6.3 (5.5) | 3.8 (3.0) | .406 |
HOMA-IR | 1.2 (1.2) | 1.5 (1.4) | 0.9 (0.8) | .471 |
. | Total Group . | GH/GnRHa . | GH . | P Value . |
---|---|---|---|---|
No. | 110 | 67 | 43 | |
Boys/girls | 51/59 | 25/42 | 26/17 | .018 |
Gestational age, wk | 37.4 (3.3) | 37.4 (3.6) | 37.5 (3.0) | .886 |
Birth weight SDS | −2.0 (1.0)a | −2.0 (0.9)a | −2.0 (1.0)a | .888 |
Birth length SDS | −2.7 (1.3)a | −2.8 (1.3)a | −2.6 (1.2)a | .513 |
Target height SDS | −0.7 (0.7)a | −0.7 (0.7)a | −0.7 (0.7)a | .849 |
Age, y | 11.4 (1.5) | 11.6 (1.2) | 11.0 (1.8) | .065 |
Height SDS | −2.9 (0.6)a | −2.9 (0.7)a | −2.9 (0.6)a | .591 |
Body mass index SDS | −1.0 (1.0) | −0.9 (1.0) | −1.2 (1.0) | .202 |
IGF-I SDS | −1.17 (1.2) | −1.08 (1.1) | −1.30 (1.5) | .374 |
Prepubertal/pubertal | 52/58 | 19/48 | 33/10 | <.001 |
Pubertal stage (14) | ||||
Tanner 1 | 52 | 19 | 33 | |
Tanner 2 | 41 | 36 | 5 | |
Tanner 3 | 17 | 12 | 5 | |
Fasting glucose, mmol/L | 5.0 (0.5) | 5.0 (0.5) | 4.9 (0.5) | .605 |
Fasting insulin, mU/L | 5.3 (4.8) | 6.3 (5.5) | 3.8 (3.0) | .406 |
HOMA-IR | 1.2 (1.2) | 1.5 (1.4) | 0.9 (0.8) | .471 |
Data are expressed as mean (SDS), unless written otherwise. Fasting insulin and HOMA-IR were square root–transformed before analyses and adjusted for Tanner stage at baseline. Bold text indicates a significant P-value (<.05)
Variables in SDS compared with 0 SDS, P < .01.
. | Total Group . | GH/GnRHa . | GH . | P Value . |
---|---|---|---|---|
No. | 110 | 67 | 43 | |
Boys/girls | 51/59 | 25/42 | 26/17 | .018 |
Gestational age, wk | 37.4 (3.3) | 37.4 (3.6) | 37.5 (3.0) | .886 |
Birth weight SDS | −2.0 (1.0)a | −2.0 (0.9)a | −2.0 (1.0)a | .888 |
Birth length SDS | −2.7 (1.3)a | −2.8 (1.3)a | −2.6 (1.2)a | .513 |
Target height SDS | −0.7 (0.7)a | −0.7 (0.7)a | −0.7 (0.7)a | .849 |
Age, y | 11.4 (1.5) | 11.6 (1.2) | 11.0 (1.8) | .065 |
Height SDS | −2.9 (0.6)a | −2.9 (0.7)a | −2.9 (0.6)a | .591 |
Body mass index SDS | −1.0 (1.0) | −0.9 (1.0) | −1.2 (1.0) | .202 |
IGF-I SDS | −1.17 (1.2) | −1.08 (1.1) | −1.30 (1.5) | .374 |
Prepubertal/pubertal | 52/58 | 19/48 | 33/10 | <.001 |
Pubertal stage (14) | ||||
Tanner 1 | 52 | 19 | 33 | |
Tanner 2 | 41 | 36 | 5 | |
Tanner 3 | 17 | 12 | 5 | |
Fasting glucose, mmol/L | 5.0 (0.5) | 5.0 (0.5) | 4.9 (0.5) | .605 |
Fasting insulin, mU/L | 5.3 (4.8) | 6.3 (5.5) | 3.8 (3.0) | .406 |
HOMA-IR | 1.2 (1.2) | 1.5 (1.4) | 0.9 (0.8) | .471 |
. | Total Group . | GH/GnRHa . | GH . | P Value . |
---|---|---|---|---|
No. | 110 | 67 | 43 | |
Boys/girls | 51/59 | 25/42 | 26/17 | .018 |
Gestational age, wk | 37.4 (3.3) | 37.4 (3.6) | 37.5 (3.0) | .886 |
Birth weight SDS | −2.0 (1.0)a | −2.0 (0.9)a | −2.0 (1.0)a | .888 |
Birth length SDS | −2.7 (1.3)a | −2.8 (1.3)a | −2.6 (1.2)a | .513 |
Target height SDS | −0.7 (0.7)a | −0.7 (0.7)a | −0.7 (0.7)a | .849 |
Age, y | 11.4 (1.5) | 11.6 (1.2) | 11.0 (1.8) | .065 |
Height SDS | −2.9 (0.6)a | −2.9 (0.7)a | −2.9 (0.6)a | .591 |
Body mass index SDS | −1.0 (1.0) | −0.9 (1.0) | −1.2 (1.0) | .202 |
IGF-I SDS | −1.17 (1.2) | −1.08 (1.1) | −1.30 (1.5) | .374 |
Prepubertal/pubertal | 52/58 | 19/48 | 33/10 | <.001 |
Pubertal stage (14) | ||||
Tanner 1 | 52 | 19 | 33 | |
Tanner 2 | 41 | 36 | 5 | |
Tanner 3 | 17 | 12 | 5 | |
Fasting glucose, mmol/L | 5.0 (0.5) | 5.0 (0.5) | 4.9 (0.5) | .605 |
Fasting insulin, mU/L | 5.3 (4.8) | 6.3 (5.5) | 3.8 (3.0) | .406 |
HOMA-IR | 1.2 (1.2) | 1.5 (1.4) | 0.9 (0.8) | .471 |
Data are expressed as mean (SDS), unless written otherwise. Fasting insulin and HOMA-IR were square root–transformed before analyses and adjusted for Tanner stage at baseline. Bold text indicates a significant P-value (<.05)
Variables in SDS compared with 0 SDS, P < .01.
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