Spearman Correlation Coefficients Estimated IS From Models 2 and 3 Compared to Measured IS
| . | WISH Study . | Adolescent Studies . | ||
|---|---|---|---|---|
| T1D (n = 12) . | Nondiabetic (n = 13) . | T1D (n = 36) . | Nondiabetic (n = 39) . | |
| Model 1, eIS | 0.83 | 0.71 | 0.44 | 0.44 |
| P value | .002 | .01 | .008 | .006 |
| Model 2, eIS-nf | 0.77 | 0.46 | 0.40 | 0.45 |
| P value | .006 | .14 | .02 | .004 |
| Model 3, eIS-exA | 0.79 | 0.58 | 0.50 | 0.44 |
| P value | .004 | .04 | .002 | .005 |
| . | WISH Study . | Adolescent Studies . | ||
|---|---|---|---|---|
| T1D (n = 12) . | Nondiabetic (n = 13) . | T1D (n = 36) . | Nondiabetic (n = 39) . | |
| Model 1, eIS | 0.83 | 0.71 | 0.44 | 0.44 |
| P value | .002 | .01 | .008 | .006 |
| Model 2, eIS-nf | 0.77 | 0.46 | 0.40 | 0.45 |
| P value | .006 | .14 | .02 | .004 |
| Model 3, eIS-exA | 0.79 | 0.58 | 0.50 | 0.44 |
| P value | .004 | .04 | .002 | .005 |
Model 1 (best-fit), T1D: eIS = exp (4.06154 − 0.01317 [waist, cm] − 1.09615 [insulin dose, daily units per kg] + 0.0202 [adiponectin, μg/mL] − 0.00307 [triglycerides, mg/dL] − 0.00733 [DBP, mm Hg]). Nondiabetic: eIS = exp (7.47237 − 0.01275 [waist, cm] − 0.24990 [HbA1c, %] − 0.01983 [fasting glucose, mg/dL] + 0.01905 [adiponectin, μg/mL] − 0.00324 [triglycerides, mg/dL] − 0.00588 [DBP, mm Hg]).
Model 2 (nonfasting), T1D: eIS = exp (4.61476 − 1.53803 [insulin dose, daily units per kg] − 0.02506 [waist, cm]). Nondiabetic: eIS = exp (6.10604 + 0.21170 [male] − 0.28233 [HbA1c, %] − 0.02293 [waist, cm]).
Model 3 (excluding adiponectin), T1D: eIS = exp (4.1075 − 0.01299 [waist, cm] − 1.05819 [insulin dose, daily units per kg] − 0.00354 [triglycerides, mg/dL] − 0.00802 [DBP, mm Hg]). Nondiabetic: eIS = exp (7.19138 + 0.10173 [male] − 0.01414 [waist, cm] − 0.33308 [HbA1c, %] − 0.01290 [fasting glucose, mg/dL] − 0.00316 [triglycerides, mg/dL]).
Spearman Correlation Coefficients Estimated IS From Models 2 and 3 Compared to Measured IS
| . | WISH Study . | Adolescent Studies . | ||
|---|---|---|---|---|
| T1D (n = 12) . | Nondiabetic (n = 13) . | T1D (n = 36) . | Nondiabetic (n = 39) . | |
| Model 1, eIS | 0.83 | 0.71 | 0.44 | 0.44 |
| P value | .002 | .01 | .008 | .006 |
| Model 2, eIS-nf | 0.77 | 0.46 | 0.40 | 0.45 |
| P value | .006 | .14 | .02 | .004 |
| Model 3, eIS-exA | 0.79 | 0.58 | 0.50 | 0.44 |
| P value | .004 | .04 | .002 | .005 |
| . | WISH Study . | Adolescent Studies . | ||
|---|---|---|---|---|
| T1D (n = 12) . | Nondiabetic (n = 13) . | T1D (n = 36) . | Nondiabetic (n = 39) . | |
| Model 1, eIS | 0.83 | 0.71 | 0.44 | 0.44 |
| P value | .002 | .01 | .008 | .006 |
| Model 2, eIS-nf | 0.77 | 0.46 | 0.40 | 0.45 |
| P value | .006 | .14 | .02 | .004 |
| Model 3, eIS-exA | 0.79 | 0.58 | 0.50 | 0.44 |
| P value | .004 | .04 | .002 | .005 |
Model 1 (best-fit), T1D: eIS = exp (4.06154 − 0.01317 [waist, cm] − 1.09615 [insulin dose, daily units per kg] + 0.0202 [adiponectin, μg/mL] − 0.00307 [triglycerides, mg/dL] − 0.00733 [DBP, mm Hg]). Nondiabetic: eIS = exp (7.47237 − 0.01275 [waist, cm] − 0.24990 [HbA1c, %] − 0.01983 [fasting glucose, mg/dL] + 0.01905 [adiponectin, μg/mL] − 0.00324 [triglycerides, mg/dL] − 0.00588 [DBP, mm Hg]).
Model 2 (nonfasting), T1D: eIS = exp (4.61476 − 1.53803 [insulin dose, daily units per kg] − 0.02506 [waist, cm]). Nondiabetic: eIS = exp (6.10604 + 0.21170 [male] − 0.28233 [HbA1c, %] − 0.02293 [waist, cm]).
Model 3 (excluding adiponectin), T1D: eIS = exp (4.1075 − 0.01299 [waist, cm] − 1.05819 [insulin dose, daily units per kg] − 0.00354 [triglycerides, mg/dL] − 0.00802 [DBP, mm Hg]). Nondiabetic: eIS = exp (7.19138 + 0.10173 [male] − 0.01414 [waist, cm] − 0.33308 [HbA1c, %] − 0.01290 [fasting glucose, mg/dL] − 0.00316 [triglycerides, mg/dL]).
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