Table 2.
Open in new tab

Linear Regression Models for the Estimation of IS in the CACTI Test Set

βR2Adjusted R2P Value
T1D
    Model 1: best fit for individual parameters0.670.64<.0001
        Constant4.06154<.0001
        Waist, cm−0.01317.054
        Insulin dose, daily dose per kg body weight−1.09615.128
        Adiponectin, μg/mL0.02027.178
        Triglycerides, mmol/L (mg/dL)−0.27168 (−0.00307).055
        DBP, mm Hg−0.00733.495
    Model 2: best model nonfasting0.610.60<.0001
        Constant4.61476<.0001
        Insulin dose, per daily dose per kg body weight−1.53803.062
        Waist, per cm−0.02506<.0001
    Model 3: best model not including adiponectin0.670.63<.0001
        Constant4.1075<.0001
        Waist (per cm)−0.01299.058
        Insulin dose, daily dose per kg body weight−1.05819.072
        Triglycerides, mmol/L (mg/dL)−0.31327 (−0.00354).027
        DBP, mm Hg−0.00802.456
Nondiabetic controls
    Model 1: best fit for individual parameters0.680.63<.0001
        Constant7.47237<.0001
        Waist, cm−0.01275.043
        Adiponectin, μg/mL0.01905.205
        HbA1c, %−0.24990.279
        Fasting glucose, mmol/L (mg/dL)−0.35730 (−0.01983).050
        Triglycerides, mmol/L (mg/dL)−0.28673 (−0.00324).043
        DBP, mm Hg−0.00588.586
    Model 2: best model nonfasting0.650.61<.0001
        Constant6.10604<.0001
        Male gender0.21170.044
        HbA1c, %−0.28233.237
        Waist, cm−0.02293.001
    Model 3: Best model not including adiponectin0.680.63<.0001
        Constant7.19138<.0001
        Male gender0.10173.279
        Waist, cm−0.01414.080
        HbA1c, %−0.33308.157
        Fasting glucose, mmol/L (mg/dL)−0.23243 (−0.01290).228
        Triglycerides, mmol/L (mg/dL)−0.27965 (−0.00316).054
    Model 4: best model including HOMA-IR0.660.63<.0001
        Constant4.08207<.0001
        Male gender−0.03170.842
        Waist, cm−0.01673.034
        HOMA-IR−0.17438.026
        Adiponectin, μg/mL0.02231.238
βR2Adjusted R2P Value
T1D
    Model 1: best fit for individual parameters0.670.64<.0001
        Constant4.06154<.0001
        Waist, cm−0.01317.054
        Insulin dose, daily dose per kg body weight−1.09615.128
        Adiponectin, μg/mL0.02027.178
        Triglycerides, mmol/L (mg/dL)−0.27168 (−0.00307).055
        DBP, mm Hg−0.00733.495
    Model 2: best model nonfasting0.610.60<.0001
        Constant4.61476<.0001
        Insulin dose, per daily dose per kg body weight−1.53803.062
        Waist, per cm−0.02506<.0001
    Model 3: best model not including adiponectin0.670.63<.0001
        Constant4.1075<.0001
        Waist (per cm)−0.01299.058
        Insulin dose, daily dose per kg body weight−1.05819.072
        Triglycerides, mmol/L (mg/dL)−0.31327 (−0.00354).027
        DBP, mm Hg−0.00802.456
Nondiabetic controls
    Model 1: best fit for individual parameters0.680.63<.0001
        Constant7.47237<.0001
        Waist, cm−0.01275.043
        Adiponectin, μg/mL0.01905.205
        HbA1c, %−0.24990.279
        Fasting glucose, mmol/L (mg/dL)−0.35730 (−0.01983).050
        Triglycerides, mmol/L (mg/dL)−0.28673 (−0.00324).043
        DBP, mm Hg−0.00588.586
    Model 2: best model nonfasting0.650.61<.0001
        Constant6.10604<.0001
        Male gender0.21170.044
        HbA1c, %−0.28233.237
        Waist, cm−0.02293.001
    Model 3: Best model not including adiponectin0.680.63<.0001
        Constant7.19138<.0001
        Male gender0.10173.279
        Waist, cm−0.01414.080
        HbA1c, %−0.33308.157
        Fasting glucose, mmol/L (mg/dL)−0.23243 (−0.01290).228
        Triglycerides, mmol/L (mg/dL)−0.27965 (−0.00316).054
    Model 4: best model including HOMA-IR0.660.63<.0001
        Constant4.08207<.0001
        Male gender−0.03170.842
        Waist, cm−0.01673.034
        HOMA-IR−0.17438.026
        Adiponectin, μg/mL0.02231.238
Table 2.
Open in new tab

Linear Regression Models for the Estimation of IS in the CACTI Test Set

βR2Adjusted R2P Value
T1D
    Model 1: best fit for individual parameters0.670.64<.0001
        Constant4.06154<.0001
        Waist, cm−0.01317.054
        Insulin dose, daily dose per kg body weight−1.09615.128
        Adiponectin, μg/mL0.02027.178
        Triglycerides, mmol/L (mg/dL)−0.27168 (−0.00307).055
        DBP, mm Hg−0.00733.495
    Model 2: best model nonfasting0.610.60<.0001
        Constant4.61476<.0001
        Insulin dose, per daily dose per kg body weight−1.53803.062
        Waist, per cm−0.02506<.0001
    Model 3: best model not including adiponectin0.670.63<.0001
        Constant4.1075<.0001
        Waist (per cm)−0.01299.058
        Insulin dose, daily dose per kg body weight−1.05819.072
        Triglycerides, mmol/L (mg/dL)−0.31327 (−0.00354).027
        DBP, mm Hg−0.00802.456
Nondiabetic controls
    Model 1: best fit for individual parameters0.680.63<.0001
        Constant7.47237<.0001
        Waist, cm−0.01275.043
        Adiponectin, μg/mL0.01905.205
        HbA1c, %−0.24990.279
        Fasting glucose, mmol/L (mg/dL)−0.35730 (−0.01983).050
        Triglycerides, mmol/L (mg/dL)−0.28673 (−0.00324).043
        DBP, mm Hg−0.00588.586
    Model 2: best model nonfasting0.650.61<.0001
        Constant6.10604<.0001
        Male gender0.21170.044
        HbA1c, %−0.28233.237
        Waist, cm−0.02293.001
    Model 3: Best model not including adiponectin0.680.63<.0001
        Constant7.19138<.0001
        Male gender0.10173.279
        Waist, cm−0.01414.080
        HbA1c, %−0.33308.157
        Fasting glucose, mmol/L (mg/dL)−0.23243 (−0.01290).228
        Triglycerides, mmol/L (mg/dL)−0.27965 (−0.00316).054
    Model 4: best model including HOMA-IR0.660.63<.0001
        Constant4.08207<.0001
        Male gender−0.03170.842
        Waist, cm−0.01673.034
        HOMA-IR−0.17438.026
        Adiponectin, μg/mL0.02231.238
βR2Adjusted R2P Value
T1D
    Model 1: best fit for individual parameters0.670.64<.0001
        Constant4.06154<.0001
        Waist, cm−0.01317.054
        Insulin dose, daily dose per kg body weight−1.09615.128
        Adiponectin, μg/mL0.02027.178
        Triglycerides, mmol/L (mg/dL)−0.27168 (−0.00307).055
        DBP, mm Hg−0.00733.495
    Model 2: best model nonfasting0.610.60<.0001
        Constant4.61476<.0001
        Insulin dose, per daily dose per kg body weight−1.53803.062
        Waist, per cm−0.02506<.0001
    Model 3: best model not including adiponectin0.670.63<.0001
        Constant4.1075<.0001
        Waist (per cm)−0.01299.058
        Insulin dose, daily dose per kg body weight−1.05819.072
        Triglycerides, mmol/L (mg/dL)−0.31327 (−0.00354).027
        DBP, mm Hg−0.00802.456
Nondiabetic controls
    Model 1: best fit for individual parameters0.680.63<.0001
        Constant7.47237<.0001
        Waist, cm−0.01275.043
        Adiponectin, μg/mL0.01905.205
        HbA1c, %−0.24990.279
        Fasting glucose, mmol/L (mg/dL)−0.35730 (−0.01983).050
        Triglycerides, mmol/L (mg/dL)−0.28673 (−0.00324).043
        DBP, mm Hg−0.00588.586
    Model 2: best model nonfasting0.650.61<.0001
        Constant6.10604<.0001
        Male gender0.21170.044
        HbA1c, %−0.28233.237
        Waist, cm−0.02293.001
    Model 3: Best model not including adiponectin0.680.63<.0001
        Constant7.19138<.0001
        Male gender0.10173.279
        Waist, cm−0.01414.080
        HbA1c, %−0.33308.157
        Fasting glucose, mmol/L (mg/dL)−0.23243 (−0.01290).228
        Triglycerides, mmol/L (mg/dL)−0.27965 (−0.00316).054
    Model 4: best model including HOMA-IR0.660.63<.0001
        Constant4.08207<.0001
        Male gender−0.03170.842
        Waist, cm−0.01673.034
        HOMA-IR−0.17438.026
        Adiponectin, μg/mL0.02231.238
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