Clinical and Laboratory Data of Patients With MTC Enrolled in the CT Immunoassay Interference Study
Patient ID . | Gender . | Age, y . | RET Mutation . | Years Since Thyroidectomy . | Disease Status . | CT, pg/mL . | CT-PEG, pg/mL . | Recovery, % . |
---|---|---|---|---|---|---|---|---|
A | F | 66 | Negative | 12 | B | 261 | 9 | 3.4 |
B | F | 40 | E761D | 4 | B | 36 | 0.6 | 1.7 |
C | M | 16 | V804M | 4 | B | 38 | 2.8 | 7.4 |
1 | F | 22 | C634Y | 2 | B/S | 21 754 | 18 567 | 85.3 |
2 | F | 28 | Negative | 5 | B/S | 19 800 | 18 729 | 94.6 |
3 | M | 48 | Negative | 9 | B/S | 14 070 | 12 985 | 92.3 |
4 | M | 35 | Negative | 9 | B/S | 11 795 | 7928 | 67.2 |
5 | M | 62 | Negative | 9 | B/S | 11 271 | 7642 | 67.8 |
6 | F | 44 | S891A | 4 | B/S | 10 087 | 7644 | 75.8 |
7 | F | 46 | C634Y | 1 | B/S | 9193 | 5414 | 58.9 |
8 | F | 44 | Negative | 7 | B/S | 941 | 848 | 90.1 |
9 | F | 67 | Negative | 14 | B/S | 744 | 593 | 79.7 |
10 | F | 57 | S891A | 4 | B/S | 429 | 438 | 102.1 |
11 | F | 22 | C634Y | 6 | B/S | 249 | 338 | 135.7 |
12 | M | 57 | S891A | NP | B/S | 114 | 59 | 51.7 |
13 | M | 41 | C634Y | 3 | B/S | 87 | 78 | 89.7 |
14 | F | 39 | Negative | 6 | B/S | 57 | 49 | 86.0 |
Patient ID . | Gender . | Age, y . | RET Mutation . | Years Since Thyroidectomy . | Disease Status . | CT, pg/mL . | CT-PEG, pg/mL . | Recovery, % . |
---|---|---|---|---|---|---|---|---|
A | F | 66 | Negative | 12 | B | 261 | 9 | 3.4 |
B | F | 40 | E761D | 4 | B | 36 | 0.6 | 1.7 |
C | M | 16 | V804M | 4 | B | 38 | 2.8 | 7.4 |
1 | F | 22 | C634Y | 2 | B/S | 21 754 | 18 567 | 85.3 |
2 | F | 28 | Negative | 5 | B/S | 19 800 | 18 729 | 94.6 |
3 | M | 48 | Negative | 9 | B/S | 14 070 | 12 985 | 92.3 |
4 | M | 35 | Negative | 9 | B/S | 11 795 | 7928 | 67.2 |
5 | M | 62 | Negative | 9 | B/S | 11 271 | 7642 | 67.8 |
6 | F | 44 | S891A | 4 | B/S | 10 087 | 7644 | 75.8 |
7 | F | 46 | C634Y | 1 | B/S | 9193 | 5414 | 58.9 |
8 | F | 44 | Negative | 7 | B/S | 941 | 848 | 90.1 |
9 | F | 67 | Negative | 14 | B/S | 744 | 593 | 79.7 |
10 | F | 57 | S891A | 4 | B/S | 429 | 438 | 102.1 |
11 | F | 22 | C634Y | 6 | B/S | 249 | 338 | 135.7 |
12 | M | 57 | S891A | NP | B/S | 114 | 59 | 51.7 |
13 | M | 41 | C634Y | 3 | B/S | 87 | 78 | 89.7 |
14 | F | 39 | Negative | 6 | B/S | 57 | 49 | 86.0 |
Abbreviations: F, female; M, male; NP, not performed; B, presenting only biochemical disease; B/S, presenting biochemical and structural disease. Blood serum from patients A, B, and C was suspected for CT immunofluorometric assay interference. RET mutation indicates identified germ line RET mutation. CT was measured by the in-house assay. CT-PEG and CT were measured after PEG treatment.
Clinical and Laboratory Data of Patients With MTC Enrolled in the CT Immunoassay Interference Study
Patient ID . | Gender . | Age, y . | RET Mutation . | Years Since Thyroidectomy . | Disease Status . | CT, pg/mL . | CT-PEG, pg/mL . | Recovery, % . |
---|---|---|---|---|---|---|---|---|
A | F | 66 | Negative | 12 | B | 261 | 9 | 3.4 |
B | F | 40 | E761D | 4 | B | 36 | 0.6 | 1.7 |
C | M | 16 | V804M | 4 | B | 38 | 2.8 | 7.4 |
1 | F | 22 | C634Y | 2 | B/S | 21 754 | 18 567 | 85.3 |
2 | F | 28 | Negative | 5 | B/S | 19 800 | 18 729 | 94.6 |
3 | M | 48 | Negative | 9 | B/S | 14 070 | 12 985 | 92.3 |
4 | M | 35 | Negative | 9 | B/S | 11 795 | 7928 | 67.2 |
5 | M | 62 | Negative | 9 | B/S | 11 271 | 7642 | 67.8 |
6 | F | 44 | S891A | 4 | B/S | 10 087 | 7644 | 75.8 |
7 | F | 46 | C634Y | 1 | B/S | 9193 | 5414 | 58.9 |
8 | F | 44 | Negative | 7 | B/S | 941 | 848 | 90.1 |
9 | F | 67 | Negative | 14 | B/S | 744 | 593 | 79.7 |
10 | F | 57 | S891A | 4 | B/S | 429 | 438 | 102.1 |
11 | F | 22 | C634Y | 6 | B/S | 249 | 338 | 135.7 |
12 | M | 57 | S891A | NP | B/S | 114 | 59 | 51.7 |
13 | M | 41 | C634Y | 3 | B/S | 87 | 78 | 89.7 |
14 | F | 39 | Negative | 6 | B/S | 57 | 49 | 86.0 |
Patient ID . | Gender . | Age, y . | RET Mutation . | Years Since Thyroidectomy . | Disease Status . | CT, pg/mL . | CT-PEG, pg/mL . | Recovery, % . |
---|---|---|---|---|---|---|---|---|
A | F | 66 | Negative | 12 | B | 261 | 9 | 3.4 |
B | F | 40 | E761D | 4 | B | 36 | 0.6 | 1.7 |
C | M | 16 | V804M | 4 | B | 38 | 2.8 | 7.4 |
1 | F | 22 | C634Y | 2 | B/S | 21 754 | 18 567 | 85.3 |
2 | F | 28 | Negative | 5 | B/S | 19 800 | 18 729 | 94.6 |
3 | M | 48 | Negative | 9 | B/S | 14 070 | 12 985 | 92.3 |
4 | M | 35 | Negative | 9 | B/S | 11 795 | 7928 | 67.2 |
5 | M | 62 | Negative | 9 | B/S | 11 271 | 7642 | 67.8 |
6 | F | 44 | S891A | 4 | B/S | 10 087 | 7644 | 75.8 |
7 | F | 46 | C634Y | 1 | B/S | 9193 | 5414 | 58.9 |
8 | F | 44 | Negative | 7 | B/S | 941 | 848 | 90.1 |
9 | F | 67 | Negative | 14 | B/S | 744 | 593 | 79.7 |
10 | F | 57 | S891A | 4 | B/S | 429 | 438 | 102.1 |
11 | F | 22 | C634Y | 6 | B/S | 249 | 338 | 135.7 |
12 | M | 57 | S891A | NP | B/S | 114 | 59 | 51.7 |
13 | M | 41 | C634Y | 3 | B/S | 87 | 78 | 89.7 |
14 | F | 39 | Negative | 6 | B/S | 57 | 49 | 86.0 |
Abbreviations: F, female; M, male; NP, not performed; B, presenting only biochemical disease; B/S, presenting biochemical and structural disease. Blood serum from patients A, B, and C was suspected for CT immunofluorometric assay interference. RET mutation indicates identified germ line RET mutation. CT was measured by the in-house assay. CT-PEG and CT were measured after PEG treatment.
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