Comparison of the Metabolic Variables During the MTT in Subjects With NDR and Those With DR at Diagnosis of T2DM
| Group A . | NDR (n = 454) . | DR (n = 90) . | P Value . |
|---|---|---|---|
| Fasting glucose (mmol/liter) | 9.6 (7.6–12.7) | 10.6 (8.5–13.8) | .021 |
| PPG (mmol/liter) (120 min) | 13.4 (9.8–17.3) | 15.1 (11.1–18.1) | .023 |
| AUCGlucose (0–240 min) (mmol/liter) | 11.8 (9.0–15.4) | 13.6 (9.8–16.3) | .023 |
| Fasting insulin (pmol/liter) | 61.8 (34.0–99.0) | 50.5 (33.9–86.36) | .036 |
| Postprandial insulin (pmol/liter) (120 min) | 278.5 (162.0–459.3) | 189.0 (108.3–335.5) | .001 |
| AUCInsulin (0–240 min) (pmol/liter) | 199.2 (117.7–317.2) | 130.5 (83.8–225.7) | <.001 |
| M0 (*10−9 pmol/kg/min) | 5.3 (3.1–7.8) | 3.7 (2.6–7.3) | .014 |
| M1 (*10−9 pmol/kg/min) | 16.9 (9.1–30.0) | 13.5 (7.9–23.8) | .065 |
| HOMA-B (%) | 34.9 (19.1–60.3) | 26.1 (14.7–48.2) | .044 |
| HOMA-S (%) | 59.7 (37.7–105.5) | 78.7 (45.2–108.6) | .094 |
| HOMA-IR | 1.7 (0.9–2.7) | 1.3 (0.9–2.2) | .094 |
| Group A . | NDR (n = 454) . | DR (n = 90) . | P Value . |
|---|---|---|---|
| Fasting glucose (mmol/liter) | 9.6 (7.6–12.7) | 10.6 (8.5–13.8) | .021 |
| PPG (mmol/liter) (120 min) | 13.4 (9.8–17.3) | 15.1 (11.1–18.1) | .023 |
| AUCGlucose (0–240 min) (mmol/liter) | 11.8 (9.0–15.4) | 13.6 (9.8–16.3) | .023 |
| Fasting insulin (pmol/liter) | 61.8 (34.0–99.0) | 50.5 (33.9–86.36) | .036 |
| Postprandial insulin (pmol/liter) (120 min) | 278.5 (162.0–459.3) | 189.0 (108.3–335.5) | .001 |
| AUCInsulin (0–240 min) (pmol/liter) | 199.2 (117.7–317.2) | 130.5 (83.8–225.7) | <.001 |
| M0 (*10−9 pmol/kg/min) | 5.3 (3.1–7.8) | 3.7 (2.6–7.3) | .014 |
| M1 (*10−9 pmol/kg/min) | 16.9 (9.1–30.0) | 13.5 (7.9–23.8) | .065 |
| HOMA-B (%) | 34.9 (19.1–60.3) | 26.1 (14.7–48.2) | .044 |
| HOMA-S (%) | 59.7 (37.7–105.5) | 78.7 (45.2–108.6) | .094 |
| HOMA-IR | 1.7 (0.9–2.7) | 1.3 (0.9–2.2) | .094 |
Data expressed as median (first to third interquartile range).
Comparison of the Metabolic Variables During the MTT in Subjects With NDR and Those With DR at Diagnosis of T2DM
| Group A . | NDR (n = 454) . | DR (n = 90) . | P Value . |
|---|---|---|---|
| Fasting glucose (mmol/liter) | 9.6 (7.6–12.7) | 10.6 (8.5–13.8) | .021 |
| PPG (mmol/liter) (120 min) | 13.4 (9.8–17.3) | 15.1 (11.1–18.1) | .023 |
| AUCGlucose (0–240 min) (mmol/liter) | 11.8 (9.0–15.4) | 13.6 (9.8–16.3) | .023 |
| Fasting insulin (pmol/liter) | 61.8 (34.0–99.0) | 50.5 (33.9–86.36) | .036 |
| Postprandial insulin (pmol/liter) (120 min) | 278.5 (162.0–459.3) | 189.0 (108.3–335.5) | .001 |
| AUCInsulin (0–240 min) (pmol/liter) | 199.2 (117.7–317.2) | 130.5 (83.8–225.7) | <.001 |
| M0 (*10−9 pmol/kg/min) | 5.3 (3.1–7.8) | 3.7 (2.6–7.3) | .014 |
| M1 (*10−9 pmol/kg/min) | 16.9 (9.1–30.0) | 13.5 (7.9–23.8) | .065 |
| HOMA-B (%) | 34.9 (19.1–60.3) | 26.1 (14.7–48.2) | .044 |
| HOMA-S (%) | 59.7 (37.7–105.5) | 78.7 (45.2–108.6) | .094 |
| HOMA-IR | 1.7 (0.9–2.7) | 1.3 (0.9–2.2) | .094 |
| Group A . | NDR (n = 454) . | DR (n = 90) . | P Value . |
|---|---|---|---|
| Fasting glucose (mmol/liter) | 9.6 (7.6–12.7) | 10.6 (8.5–13.8) | .021 |
| PPG (mmol/liter) (120 min) | 13.4 (9.8–17.3) | 15.1 (11.1–18.1) | .023 |
| AUCGlucose (0–240 min) (mmol/liter) | 11.8 (9.0–15.4) | 13.6 (9.8–16.3) | .023 |
| Fasting insulin (pmol/liter) | 61.8 (34.0–99.0) | 50.5 (33.9–86.36) | .036 |
| Postprandial insulin (pmol/liter) (120 min) | 278.5 (162.0–459.3) | 189.0 (108.3–335.5) | .001 |
| AUCInsulin (0–240 min) (pmol/liter) | 199.2 (117.7–317.2) | 130.5 (83.8–225.7) | <.001 |
| M0 (*10−9 pmol/kg/min) | 5.3 (3.1–7.8) | 3.7 (2.6–7.3) | .014 |
| M1 (*10−9 pmol/kg/min) | 16.9 (9.1–30.0) | 13.5 (7.9–23.8) | .065 |
| HOMA-B (%) | 34.9 (19.1–60.3) | 26.1 (14.7–48.2) | .044 |
| HOMA-S (%) | 59.7 (37.7–105.5) | 78.7 (45.2–108.6) | .094 |
| HOMA-IR | 1.7 (0.9–2.7) | 1.3 (0.9–2.2) | .094 |
Data expressed as median (first to third interquartile range).
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