Table 2. Open in new tab The Change in...

Table 2.

The Change in Clinical Characteristics, Endocrinological Variables, and mRNA Expression on Cycle Days 6–8 After Lifestyle Intervention in Overweight/Obese Women With PCOS

	Change n = 18
BMI	−1.6 ± 1.5^a
Weight (kg)	−4.8 ± 4.3^a
Endometrial thickness (mm)	−0.9 ± 2.5
Endocrinological variables
LH (IU/I)	1.8 ± 2.5^b
FSH (IU/I)	0.9 ± 1.3^c
Total testosterone (nmol/liter)	−0.1 ± 0.7
SHBG (nmol/liter)	0.1 ± 14.2
Free testosterone (pmol/liter)	−3.5 ± 23.8
Estradiol (pmol/liter)	−18.1 ± 102.3
Insulin (mIU/liter)	−24.5 ± 37.3^b
Relative mRNA expression
ERα	0.06 (−0.2 to 0.4)
ERβ	−0.03 (−0.09 to 0.02)
ERα/ERβ ratio	0.5 (−0.5 to 1.5)
ERα36	−0.03 (−0.09 to 0.02)
GPER	−0.03 (−0.09 to 0.02)^c
GPER/ERα36 ratio	−0.02 (−0.2 to 0.05)
AR	0.4 (−0.2 to 1.3)

	Change n = 18
BMI	−1.6 ± 1.5^a
Weight (kg)	−4.8 ± 4.3^a
Endometrial thickness (mm)	−0.9 ± 2.5
Endocrinological variables
LH (IU/I)	1.8 ± 2.5^b
FSH (IU/I)	0.9 ± 1.3^c
Total testosterone (nmol/liter)	−0.1 ± 0.7
SHBG (nmol/liter)	0.1 ± 14.2
Free testosterone (pmol/liter)	−3.5 ± 23.8
Estradiol (pmol/liter)	−18.1 ± 102.3
Insulin (mIU/liter)	−24.5 ± 37.3^b
Relative mRNA expression
ERα	0.06 (−0.2 to 0.4)
ERβ	−0.03 (−0.09 to 0.02)
ERα/ERβ ratio	0.5 (−0.5 to 1.5)
ERα36	−0.03 (−0.09 to 0.02)
GPER	−0.03 (−0.09 to 0.02)^c
GPER/ERα36 ratio	−0.02 (−0.2 to 0.05)
AR	0.4 (−0.2 to 1.3)

The before values for the OB-PCOS women are presented in Table 1. The values are presented as means ± sd or medians with quartile range (25th–75th quartiles).

Significant changes compared to before lifestyle intervention as follows:

P < .001;

P < .01;

P < .05.

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