Estimates of the Number of Divergent Sites and the Fraction of Divergence Driven to Fixation by Positive Selection, α (with 90% CIs) for Coding and Noncoding DNA in Drosophila simulans and Drosophila melanogaster, Using Loci Overlapping between This Study and Andolfatto (2005)
Lineage | NonSyna | Introns | 5′ UTRs | 3′ UTRs |
Divergence | ||||
sim–melb | 123 | 187 | 161 | 138 |
simc | 57 | 53 | 67 | 51 |
mel–simd | 132 | 227 | 138 | 151 |
mele | 62 | 74 | 65 | 81 |
αf | ||||
sim–melb | 0.63 (0.39–0.77) | 0.51 (0.25–0.67) | 0.66 (0.49–0.79) | 0.49 (0.18–0.67) |
simc | 0.66 (0.41–0.81) | 0.22 (−0.27 to 0.53) | 0.63 (0.38–0.79) | 0.64 (0.35–0.80) |
mel–simd | 0.68 (0.54–0.81) | 0.04 (−0.23 to 0.24) | 0.43 (0.22–0.60) | 0.75 (0.64–0.85) |
mele | 0.71 (0.56–0.82) | −0.29 (−0.76 to 0.06) | 0.41 (0.14–0.60) | 0.79 (0.67–0.88) |
Lineage | NonSyna | Introns | 5′ UTRs | 3′ UTRs |
Divergence | ||||
sim–melb | 123 | 187 | 161 | 138 |
simc | 57 | 53 | 67 | 51 |
mel–simd | 132 | 227 | 138 | 151 |
mele | 62 | 74 | 65 | 81 |
αf | ||||
sim–melb | 0.63 (0.39–0.77) | 0.51 (0.25–0.67) | 0.66 (0.49–0.79) | 0.49 (0.18–0.67) |
simc | 0.66 (0.41–0.81) | 0.22 (−0.27 to 0.53) | 0.63 (0.38–0.79) | 0.64 (0.35–0.80) |
mel–simd | 0.68 (0.54–0.81) | 0.04 (−0.23 to 0.24) | 0.43 (0.22–0.60) | 0.75 (0.64–0.85) |
mele | 0.71 (0.56–0.82) | −0.29 (−0.76 to 0.06) | 0.41 (0.14–0.60) | 0.79 (0.67–0.88) |
Nonsynonymous sites.
Estimates using D. simulans polymorphism and divergence to D. melanogaster.
Drosophila simulans lineage-specific estimates.
Estimates using D. melanogaster polymorphism and divergence to D. simulans.
Drosophila melanogaster lineage-specific estimates.
Estimates of α were calculated using only P → P/U → U synonymous sites in D. simulans but using all synonymous sites in D. melanogaster. Polymorphisms at a frequency of up to 10% were excluded in all cases.
Estimates of the Number of Divergent Sites and the Fraction of Divergence Driven to Fixation by Positive Selection, α (with 90% CIs) for Coding and Noncoding DNA in Drosophila simulans and Drosophila melanogaster, Using Loci Overlapping between This Study and Andolfatto (2005)
Lineage | NonSyna | Introns | 5′ UTRs | 3′ UTRs |
Divergence | ||||
sim–melb | 123 | 187 | 161 | 138 |
simc | 57 | 53 | 67 | 51 |
mel–simd | 132 | 227 | 138 | 151 |
mele | 62 | 74 | 65 | 81 |
αf | ||||
sim–melb | 0.63 (0.39–0.77) | 0.51 (0.25–0.67) | 0.66 (0.49–0.79) | 0.49 (0.18–0.67) |
simc | 0.66 (0.41–0.81) | 0.22 (−0.27 to 0.53) | 0.63 (0.38–0.79) | 0.64 (0.35–0.80) |
mel–simd | 0.68 (0.54–0.81) | 0.04 (−0.23 to 0.24) | 0.43 (0.22–0.60) | 0.75 (0.64–0.85) |
mele | 0.71 (0.56–0.82) | −0.29 (−0.76 to 0.06) | 0.41 (0.14–0.60) | 0.79 (0.67–0.88) |
Lineage | NonSyna | Introns | 5′ UTRs | 3′ UTRs |
Divergence | ||||
sim–melb | 123 | 187 | 161 | 138 |
simc | 57 | 53 | 67 | 51 |
mel–simd | 132 | 227 | 138 | 151 |
mele | 62 | 74 | 65 | 81 |
αf | ||||
sim–melb | 0.63 (0.39–0.77) | 0.51 (0.25–0.67) | 0.66 (0.49–0.79) | 0.49 (0.18–0.67) |
simc | 0.66 (0.41–0.81) | 0.22 (−0.27 to 0.53) | 0.63 (0.38–0.79) | 0.64 (0.35–0.80) |
mel–simd | 0.68 (0.54–0.81) | 0.04 (−0.23 to 0.24) | 0.43 (0.22–0.60) | 0.75 (0.64–0.85) |
mele | 0.71 (0.56–0.82) | −0.29 (−0.76 to 0.06) | 0.41 (0.14–0.60) | 0.79 (0.67–0.88) |
Nonsynonymous sites.
Estimates using D. simulans polymorphism and divergence to D. melanogaster.
Drosophila simulans lineage-specific estimates.
Estimates using D. melanogaster polymorphism and divergence to D. simulans.
Drosophila melanogaster lineage-specific estimates.
Estimates of α were calculated using only P → P/U → U synonymous sites in D. simulans but using all synonymous sites in D. melanogaster. Polymorphisms at a frequency of up to 10% were excluded in all cases.
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