Table 2. Open in new tab Association of...

	SNP	Position	Allele^a	Hemoglobin Level	Degree of Blood Oxygen Saturation
Male	rs2486745	231505717	C	261	0.25	0.26	0.33	/	262	−1.16	1.12	0.30	/
rs2491406	231518665	A	261	0.29	0.25	0.26	/	262	−1.12	1.10	0.31	/
rs2491407	231518928	A	261	0.29	0.25	0.26	/	262	−1.12	1.10	0.31	/
rs2739506	231529183	G	261	0.29	0.25	0.26	/	262	−1.12	1.10	0.31	/
rs2244986	231537452	T	261	0.28	0.26	0.27	/	262	−1.37	1.11	0.22	/
rs11805033	231546452	T	261	0.25	0.26	0.32	/	262	−1.09	1.10	0.33	/
rs12097901	231557255	C	261	0.61	0.27	0.022	0.061	262	−1.93	1.16	0.097	/
rs186996510	231557623	G	261	0.62	0.23	0.0067	0.023	262	−1.67	0.99	0.092	/
Female	rs2486745	231505717	C	355	−0.10	0.25	0.69	/	356	−0.55	0.85	0.52	/
rs2491406	231518665	A	355	−0.08	0.25	0.73	/	356	−0.61	0.85	0.47	/
rs2491407	231518928	A	355	−0.08	0.25	0.73	/	356	−0.61	0.85	0.47	/
rs2739506	231529183	G	355	−0.11	0.24	0.65	/	356	−0.52	0.85	0.54	/
rs2244986	231537452	T	355	−0.13	0.25	0.61	/	356	−0.58	0.86	0.50	/
rs11805033	231546452	T	355	−0.10	0.25	0.69	/	356	−0.55	0.85	0.52	/
rs12097901	231557255	C	355	0.19	0.25	0.43	/	356	−0.40	0.85	0.64	/
rs186996510	231557623	G	355	0.20	0.22	0.37	/	356	−1.01	0.76	0.19	/
All	rs2486745	231505717	C	616	0.08	0.18	0.66	/	618	−0.85	0.68	0.21	/
rs2491406	231518665	A	616	0.10	0.18	0.56	/	618	−0.87	0.67	0.20	/
rs2491407	231518928	A	616	0.10	0.18	0.56	/	618	−0.87	0.67	0.20	/
rs2739506	231529183	G	616	0.08	0.18	0.63	/	618	−0.82	0.67	0.23	/
rs2244986	231537452	T	616	0.09	0.18	0.63	/	618	−0.97	0.68	0.15	/
rs11805033	231546452	T	616	0.08	0.18	0.65	/	618	−0.82	0.67	0.22	/
rs12097901	231557255	C	616	0.37	0.18	0.039	0.091	618	−1.04	0.69	0.14	/
rs186996510	231557623	G	616	0.38	0.16	0.018	0.049	618	−1.29	0.61	0.034	0.086

SNP

Position

Allele^a

Hemoglobin Level

Degree of Blood Oxygen Saturation

Corrected P

Male

rs2486745

231505717

261

0.25

0.26

0.33

262

−1.16

1.12

0.30

rs2491406

231518665

261

0.29

0.25

0.26

262

−1.12

1.10

0.31

rs2491407

231518928

261

0.29

0.25

0.26

262

−1.12

1.10

0.31

rs2739506

231529183

261

0.29

0.25

0.26

262

−1.12

1.10

0.31

rs2244986

231537452

261

0.28

0.26

0.27

262

−1.37

1.11

0.22

rs11805033

231546452

261

0.25

0.26

0.32

262

−1.09

1.10

0.33

rs12097901

231557255

261

0.61

0.27

0.022

0.061

262

−1.93

1.16

0.097

rs186996510

231557623

261

0.62

0.23

0.0067

0.023

262

−1.67

0.99

0.092

Female

rs2486745

231505717

355

−0.10

0.25

0.69

356

−0.55

0.85

0.52

rs2491406

231518665

355

−0.08

0.25

0.73

356

−0.61

0.85

0.47

rs2491407

231518928

355

−0.08

0.25

0.73

356

−0.61

0.85

0.47

rs2739506

231529183

355

−0.11

0.24

0.65

356

−0.52

0.85

0.54

rs2244986

231537452

355

−0.13

0.25

0.61

356

−0.58

0.86

0.50

rs11805033

231546452

355

−0.10

0.25

0.69

356

−0.55

0.85

0.52

rs12097901

231557255

355

0.19

0.25

0.43

356

−0.40

0.85

0.64

rs186996510

231557623

355

0.20

0.22

0.37

356

−1.01

0.76

0.19

All

rs2486745

231505717

616

0.08

0.18

0.66

618

−0.85

0.68

0.21

rs2491406

231518665

616

0.10

0.18

0.56

618

−0.87

0.67

0.20

rs2491407

231518928

616

0.10

0.18

0.56

618

−0.87

0.67

0.20

rs2739506

231529183

616

0.08

0.18

0.63

618

−0.82

0.67

0.23

rs2244986

231537452

616

0.09

0.18

0.63

618

−0.97

0.68

0.15

rs11805033

231546452

616

0.08

0.18

0.65

618

−0.82

0.67

0.22

rs12097901

231557255

616

0.37

0.18

0.039

0.091

618

−1.04

0.69

0.14

rs186996510

231557623

616

0.38

0.16

0.018

0.049

618

−1.29

0.61

0.034

0.086

	SNP	Position	Allele^a	Hemoglobin Level	Degree of Blood Oxygen Saturation
Male	rs2486745	231505717	C	261	0.25	0.26	0.33	/	262	−1.16	1.12	0.30	/
rs2491406	231518665	A	261	0.29	0.25	0.26	/	262	−1.12	1.10	0.31	/
rs2491407	231518928	A	261	0.29	0.25	0.26	/	262	−1.12	1.10	0.31	/
rs2739506	231529183	G	261	0.29	0.25	0.26	/	262	−1.12	1.10	0.31	/
rs2244986	231537452	T	261	0.28	0.26	0.27	/	262	−1.37	1.11	0.22	/
rs11805033	231546452	T	261	0.25	0.26	0.32	/	262	−1.09	1.10	0.33	/
rs12097901	231557255	C	261	0.61	0.27	0.022	0.061	262	−1.93	1.16	0.097	/
rs186996510	231557623	G	261	0.62	0.23	0.0067	0.023	262	−1.67	0.99	0.092	/
Female	rs2486745	231505717	C	355	−0.10	0.25	0.69	/	356	−0.55	0.85	0.52	/
rs2491406	231518665	A	355	−0.08	0.25	0.73	/	356	−0.61	0.85	0.47	/
rs2491407	231518928	A	355	−0.08	0.25	0.73	/	356	−0.61	0.85	0.47	/
rs2739506	231529183	G	355	−0.11	0.24	0.65	/	356	−0.52	0.85	0.54	/
rs2244986	231537452	T	355	−0.13	0.25	0.61	/	356	−0.58	0.86	0.50	/
rs11805033	231546452	T	355	−0.10	0.25	0.69	/	356	−0.55	0.85	0.52	/
rs12097901	231557255	C	355	0.19	0.25	0.43	/	356	−0.40	0.85	0.64	/
rs186996510	231557623	G	355	0.20	0.22	0.37	/	356	−1.01	0.76	0.19	/
All	rs2486745	231505717	C	616	0.08	0.18	0.66	/	618	−0.85	0.68	0.21	/
rs2491406	231518665	A	616	0.10	0.18	0.56	/	618	−0.87	0.67	0.20	/
rs2491407	231518928	A	616	0.10	0.18	0.56	/	618	−0.87	0.67	0.20	/
rs2739506	231529183	G	616	0.08	0.18	0.63	/	618	−0.82	0.67	0.23	/
rs2244986	231537452	T	616	0.09	0.18	0.63	/	618	−0.97	0.68	0.15	/
rs11805033	231546452	T	616	0.08	0.18	0.65	/	618	−0.82	0.67	0.22	/
rs12097901	231557255	C	616	0.37	0.18	0.039	0.091	618	−1.04	0.69	0.14	/
rs186996510	231557623	G	616	0.38	0.16	0.018	0.049	618	−1.29	0.61	0.034	0.086

Table 2.

Open in new tab

Association of Eight EGLN1 SNPs with Levels of Hemoglobin and Blood Oxygen Saturation in Tibetans.

	SNP	Position	Allele^a	Hemoglobin Level					Degree of Blood Oxygen Saturation
	SNP	Position	Allele^a	N	β	SE	P	Corrected P	N	β	SE	P	Corrected P
Male	rs2486745	231505717	C	261	0.25	0.26	0.33	/	262	−1.16	1.12	0.30	/
	rs2491406	231518665	A	261	0.29	0.25	0.26	/	262	−1.12	1.10	0.31	/
	rs2491407	231518928	A	261	0.29	0.25	0.26	/	262	−1.12	1.10	0.31	/
	rs2739506	231529183	G	261	0.29	0.25	0.26	/	262	−1.12	1.10	0.31	/
	rs2244986	231537452	T	261	0.28	0.26	0.27	/	262	−1.37	1.11	0.22	/
	rs11805033	231546452	T	261	0.25	0.26	0.32	/	262	−1.09	1.10	0.33	/
	rs12097901	231557255	C	261	0.61	0.27	0.022	0.061	262	−1.93	1.16	0.097	/
	rs186996510	231557623	G	261	0.62	0.23	0.0067	0.023	262	−1.67	0.99	0.092	/
Female	rs2486745	231505717	C	355	−0.10	0.25	0.69	/	356	−0.55	0.85	0.52	/
	rs2491406	231518665	A	355	−0.08	0.25	0.73	/	356	−0.61	0.85	0.47	/
	rs2491407	231518928	A	355	−0.08	0.25	0.73	/	356	−0.61	0.85	0.47	/
	rs2739506	231529183	G	355	−0.11	0.24	0.65	/	356	−0.52	0.85	0.54	/
	rs2244986	231537452	T	355	−0.13	0.25	0.61	/	356	−0.58	0.86	0.50	/
	rs11805033	231546452	T	355	−0.10	0.25	0.69	/	356	−0.55	0.85	0.52	/
	rs12097901	231557255	C	355	0.19	0.25	0.43	/	356	−0.40	0.85	0.64	/
	rs186996510	231557623	G	355	0.20	0.22	0.37	/	356	−1.01	0.76	0.19	/
All	rs2486745	231505717	C	616	0.08	0.18	0.66	/	618	−0.85	0.68	0.21	/
	rs2491406	231518665	A	616	0.10	0.18	0.56	/	618	−0.87	0.67	0.20	/
	rs2491407	231518928	A	616	0.10	0.18	0.56	/	618	−0.87	0.67	0.20	/
	rs2739506	231529183	G	616	0.08	0.18	0.63	/	618	−0.82	0.67	0.23	/
	rs2244986	231537452	T	616	0.09	0.18	0.63	/	618	−0.97	0.68	0.15	/
	rs11805033	231546452	T	616	0.08	0.18	0.65	/	618	−0.82	0.67	0.22	/
	rs12097901	231557255	C	616	0.37	0.18	0.039	0.091	618	−1.04	0.69	0.14	/
	rs186996510	231557623	G	616	0.38	0.16	0.018	0.049	618	−1.29	0.61	0.034	0.086

	SNP	Position	Allele^a	Hemoglobin Level					Degree of Blood Oxygen Saturation
	SNP	Position	Allele^a	N	β	SE	P	Corrected P	N	β	SE	P	Corrected P
Male	rs2486745	231505717	C	261	0.25	0.26	0.33	/	262	−1.16	1.12	0.30	/
	rs2491406	231518665	A	261	0.29	0.25	0.26	/	262	−1.12	1.10	0.31	/
	rs2491407	231518928	A	261	0.29	0.25	0.26	/	262	−1.12	1.10	0.31	/
	rs2739506	231529183	G	261	0.29	0.25	0.26	/	262	−1.12	1.10	0.31	/
	rs2244986	231537452	T	261	0.28	0.26	0.27	/	262	−1.37	1.11	0.22	/
	rs11805033	231546452	T	261	0.25	0.26	0.32	/	262	−1.09	1.10	0.33	/
	rs12097901	231557255	C	261	0.61	0.27	0.022	0.061	262	−1.93	1.16	0.097	/
	rs186996510	231557623	G	261	0.62	0.23	0.0067	0.023	262	−1.67	0.99	0.092	/
Female	rs2486745	231505717	C	355	−0.10	0.25	0.69	/	356	−0.55	0.85	0.52	/
	rs2491406	231518665	A	355	−0.08	0.25	0.73	/	356	−0.61	0.85	0.47	/
	rs2491407	231518928	A	355	−0.08	0.25	0.73	/	356	−0.61	0.85	0.47	/
	rs2739506	231529183	G	355	−0.11	0.24	0.65	/	356	−0.52	0.85	0.54	/
	rs2244986	231537452	T	355	−0.13	0.25	0.61	/	356	−0.58	0.86	0.50	/
	rs11805033	231546452	T	355	−0.10	0.25	0.69	/	356	−0.55	0.85	0.52	/
	rs12097901	231557255	C	355	0.19	0.25	0.43	/	356	−0.40	0.85	0.64	/
	rs186996510	231557623	G	355	0.20	0.22	0.37	/	356	−1.01	0.76	0.19	/
All	rs2486745	231505717	C	616	0.08	0.18	0.66	/	618	−0.85	0.68	0.21	/
	rs2491406	231518665	A	616	0.10	0.18	0.56	/	618	−0.87	0.67	0.20	/
	rs2491407	231518928	A	616	0.10	0.18	0.56	/	618	−0.87	0.67	0.20	/
	rs2739506	231529183	G	616	0.08	0.18	0.63	/	618	−0.82	0.67	0.23	/
	rs2244986	231537452	T	616	0.09	0.18	0.63	/	618	−0.97	0.68	0.15	/
	rs11805033	231546452	T	616	0.08	0.18	0.65	/	618	−0.82	0.67	0.22	/
	rs12097901	231557255	C	616	0.37	0.18	0.039	0.091	618	−1.04	0.69	0.14	/
	rs186996510	231557623	G	616	0.38	0.16	0.018	0.049	618	−1.29	0.61	0.034	0.086

Note.—Significant results are underlined. β, the difference per copy increase of the effect allele; SE, standard error; N, number of tested individuals for the SNP.

^aEffect allele.

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