Table 1.

Baseline Characteristics by AHA-Defined Categories of PA: ARIC Study (1987–1989)

AHA-PA Categories at ARIC Visit 1OverallRecommendedIntermediatePoorPa
Patients, no.10,342409526713576
METS*min/wkb402.0 (0.0–993.6)1175.9 (874.8–1700.1)339.3 (189.0–489.0)0.0 (0.0–0.0)
Age, y53.8 ± 5.754.1 ± 5.753.7 ± 5.753.5 ± 5.6<0.001
25(OH)D, ng/mLc,d24.7 ± 8.526.6 ± 8.324.4 ± 8.222.7 ± 8.3<0.001
Vitamin D supplement usee3279 (31.7)1440 (35.2)891 (33.4)948 (26.5)<0.001
Total cholesterol, mg/dLc214.3 ± 40.9213.2 ± 39.4214.9 ± 41.6215.0 ± 42.00.11
HDL, mg/dLc52.6 ± 16.953.2 ± 17.352.4 ± 16.252.0 ± 17.1<0.001
LDL, mg/dLc136.7 ± 38.3135.6 ± 37.4137.4 ± 38.5137.4 ± 39.10.06
Triglycerides, mg/dLc127.4 ± 84.1124.3 ± 80.2128.1 ± 82.3130.5 ± 89.60.01
BMI, kg/m227.4 ± 5.126.6 ± 4.427.1 ± 5.028.4 ± 5.7<0.001
Men4396 (42.5)1962 (47.9)1025 (38.4)1409 (39.4)<0.001
Center/race<0.001
 Minneapolis, MN/white2963 (28.7)1423 (34.7)817 (30.6)723 (20.2)
 Washington Co., MD/white2770 (26.8)1095 (26.7)730 (27.3)945 (26.4)
 Forsyth Co., NC/white2468 (23.9)1103 (26.9)649 (24.3)716 (20.0)
 Forsyth Co., NC/black241 (2.3)82 (2.0)88 (3.3)71 (2.0)
 Jackson, MI/black1900 (18.4)392 (9.6)387 (14.5)1121 (31.3)
Education<0.001
 < High school1898 (18.4)478 (11.7)424 (15.9)996 (27.9)
 High school or vocational school4401 (42.6)1669 (40.8)1180 (44.2)1552 (43.4)
 College, graduate, or professional school4043 (39.1)1948 (47.6)1067 (39.9)1028 (28.7)
Smoking status<0.001
 Never4720 (45.6)1861 (45.4)1275 (47.7)1584 (44.3)
 Former3353 (32.4)1499 (36.6)831 (31.1)1023 (28.6)
 Current2269 (21.9)735 (17.9)565 (21.2)969 (27.1)
Current alcohol consumption6114 (59.1)2733 (66.7)1607 (60.2)1774 (49.6)<0.001
Diabetes890 (8.6)282 (6.9)221 (8.3)387 (10.8)<0.001
SBP, mm Hg119.5 ± 17.4118.2 ± 16.8118.7 ± 17.0121.5 ± 18.0<0.001
Hypertension2970 (28.8)1013 (24.8)732 (27.5)1225 (34.4)<0.001
AST, U/Lb,d20.0 (17.0–23.0)20.0 (17.0–23.0)20.0 (17.0–23.0)19.0 (16.0–23.0)<0.001
ALT, U/Lb,d15.0 (11.0–19.0)15.0 (11.0–19.0)15.0 (11.0–19.0)14.0 (11.0–19.0)0.05
GGT, U/Lb,d20.0 (14.0–32.0)20.0 (14.0–30.0)20.0 (14.0–31.0)22.0 (15.0–34.0)<0.001
eGFR, mL/min/1.73 m2<0.001
 ≥908776 (84.9)3406 (83.2)2262 (84.7)3108 (86.9)
 60–<901489 (14.4)660 (16.1)383 (14.3)446 (12.5)
 <6077 (0.7)29 (0.7)26 (1.0)22 (0.6)
AHA-PA Categories at ARIC Visit 1OverallRecommendedIntermediatePoorPa
Patients, no.10,342409526713576
METS*min/wkb402.0 (0.0–993.6)1175.9 (874.8–1700.1)339.3 (189.0–489.0)0.0 (0.0–0.0)
Age, y53.8 ± 5.754.1 ± 5.753.7 ± 5.753.5 ± 5.6<0.001
25(OH)D, ng/mLc,d24.7 ± 8.526.6 ± 8.324.4 ± 8.222.7 ± 8.3<0.001
Vitamin D supplement usee3279 (31.7)1440 (35.2)891 (33.4)948 (26.5)<0.001
Total cholesterol, mg/dLc214.3 ± 40.9213.2 ± 39.4214.9 ± 41.6215.0 ± 42.00.11
HDL, mg/dLc52.6 ± 16.953.2 ± 17.352.4 ± 16.252.0 ± 17.1<0.001
LDL, mg/dLc136.7 ± 38.3135.6 ± 37.4137.4 ± 38.5137.4 ± 39.10.06
Triglycerides, mg/dLc127.4 ± 84.1124.3 ± 80.2128.1 ± 82.3130.5 ± 89.60.01
BMI, kg/m227.4 ± 5.126.6 ± 4.427.1 ± 5.028.4 ± 5.7<0.001
Men4396 (42.5)1962 (47.9)1025 (38.4)1409 (39.4)<0.001
Center/race<0.001
 Minneapolis, MN/white2963 (28.7)1423 (34.7)817 (30.6)723 (20.2)
 Washington Co., MD/white2770 (26.8)1095 (26.7)730 (27.3)945 (26.4)
 Forsyth Co., NC/white2468 (23.9)1103 (26.9)649 (24.3)716 (20.0)
 Forsyth Co., NC/black241 (2.3)82 (2.0)88 (3.3)71 (2.0)
 Jackson, MI/black1900 (18.4)392 (9.6)387 (14.5)1121 (31.3)
Education<0.001
 < High school1898 (18.4)478 (11.7)424 (15.9)996 (27.9)
 High school or vocational school4401 (42.6)1669 (40.8)1180 (44.2)1552 (43.4)
 College, graduate, or professional school4043 (39.1)1948 (47.6)1067 (39.9)1028 (28.7)
Smoking status<0.001
 Never4720 (45.6)1861 (45.4)1275 (47.7)1584 (44.3)
 Former3353 (32.4)1499 (36.6)831 (31.1)1023 (28.6)
 Current2269 (21.9)735 (17.9)565 (21.2)969 (27.1)
Current alcohol consumption6114 (59.1)2733 (66.7)1607 (60.2)1774 (49.6)<0.001
Diabetes890 (8.6)282 (6.9)221 (8.3)387 (10.8)<0.001
SBP, mm Hg119.5 ± 17.4118.2 ± 16.8118.7 ± 17.0121.5 ± 18.0<0.001
Hypertension2970 (28.8)1013 (24.8)732 (27.5)1225 (34.4)<0.001
AST, U/Lb,d20.0 (17.0–23.0)20.0 (17.0–23.0)20.0 (17.0–23.0)19.0 (16.0–23.0)<0.001
ALT, U/Lb,d15.0 (11.0–19.0)15.0 (11.0–19.0)15.0 (11.0–19.0)14.0 (11.0–19.0)0.05
GGT, U/Lb,d20.0 (14.0–32.0)20.0 (14.0–30.0)20.0 (14.0–31.0)22.0 (15.0–34.0)<0.001
eGFR, mL/min/1.73 m2<0.001
 ≥908776 (84.9)3406 (83.2)2262 (84.7)3108 (86.9)
 60–<901489 (14.4)660 (16.1)383 (14.3)446 (12.5)
 <6077 (0.7)29 (0.7)26 (1.0)22 (0.6)

Data are given as mean ± standard deviation or number (%) unless otherwise noted.

Abbreviations: ALT, alanine aminotransferase; AST, aspartate aminotransferase; Co., County; GGT, gamma-glutamyl transferase.

a

P value comparing trend of characteristics across the PA categories of Recommended, Intermediate, and Poor.

b

Median (25th to 75th percentile).

c

To convert 25(OH)D levels to nmol/L from ng/mL, multiply by 2.496. To convert the units of measure of total cholesterol, HDL-C, and LDL-C to mmol/L from mg/dL, divide by 38.67. To convert the unit of measure of triglyceride to mmol/L from mg/dL, divide by 88.57.

d

From ARIC visit 2 (1990 to 1992).

e

From ARIC visit 3 (1993 to 1995).

Table 1.

Baseline Characteristics by AHA-Defined Categories of PA: ARIC Study (1987–1989)

AHA-PA Categories at ARIC Visit 1OverallRecommendedIntermediatePoorPa
Patients, no.10,342409526713576
METS*min/wkb402.0 (0.0–993.6)1175.9 (874.8–1700.1)339.3 (189.0–489.0)0.0 (0.0–0.0)
Age, y53.8 ± 5.754.1 ± 5.753.7 ± 5.753.5 ± 5.6<0.001
25(OH)D, ng/mLc,d24.7 ± 8.526.6 ± 8.324.4 ± 8.222.7 ± 8.3<0.001
Vitamin D supplement usee3279 (31.7)1440 (35.2)891 (33.4)948 (26.5)<0.001
Total cholesterol, mg/dLc214.3 ± 40.9213.2 ± 39.4214.9 ± 41.6215.0 ± 42.00.11
HDL, mg/dLc52.6 ± 16.953.2 ± 17.352.4 ± 16.252.0 ± 17.1<0.001
LDL, mg/dLc136.7 ± 38.3135.6 ± 37.4137.4 ± 38.5137.4 ± 39.10.06
Triglycerides, mg/dLc127.4 ± 84.1124.3 ± 80.2128.1 ± 82.3130.5 ± 89.60.01
BMI, kg/m227.4 ± 5.126.6 ± 4.427.1 ± 5.028.4 ± 5.7<0.001
Men4396 (42.5)1962 (47.9)1025 (38.4)1409 (39.4)<0.001
Center/race<0.001
 Minneapolis, MN/white2963 (28.7)1423 (34.7)817 (30.6)723 (20.2)
 Washington Co., MD/white2770 (26.8)1095 (26.7)730 (27.3)945 (26.4)
 Forsyth Co., NC/white2468 (23.9)1103 (26.9)649 (24.3)716 (20.0)
 Forsyth Co., NC/black241 (2.3)82 (2.0)88 (3.3)71 (2.0)
 Jackson, MI/black1900 (18.4)392 (9.6)387 (14.5)1121 (31.3)
Education<0.001
 < High school1898 (18.4)478 (11.7)424 (15.9)996 (27.9)
 High school or vocational school4401 (42.6)1669 (40.8)1180 (44.2)1552 (43.4)
 College, graduate, or professional school4043 (39.1)1948 (47.6)1067 (39.9)1028 (28.7)
Smoking status<0.001
 Never4720 (45.6)1861 (45.4)1275 (47.7)1584 (44.3)
 Former3353 (32.4)1499 (36.6)831 (31.1)1023 (28.6)
 Current2269 (21.9)735 (17.9)565 (21.2)969 (27.1)
Current alcohol consumption6114 (59.1)2733 (66.7)1607 (60.2)1774 (49.6)<0.001
Diabetes890 (8.6)282 (6.9)221 (8.3)387 (10.8)<0.001
SBP, mm Hg119.5 ± 17.4118.2 ± 16.8118.7 ± 17.0121.5 ± 18.0<0.001
Hypertension2970 (28.8)1013 (24.8)732 (27.5)1225 (34.4)<0.001
AST, U/Lb,d20.0 (17.0–23.0)20.0 (17.0–23.0)20.0 (17.0–23.0)19.0 (16.0–23.0)<0.001
ALT, U/Lb,d15.0 (11.0–19.0)15.0 (11.0–19.0)15.0 (11.0–19.0)14.0 (11.0–19.0)0.05
GGT, U/Lb,d20.0 (14.0–32.0)20.0 (14.0–30.0)20.0 (14.0–31.0)22.0 (15.0–34.0)<0.001
eGFR, mL/min/1.73 m2<0.001
 ≥908776 (84.9)3406 (83.2)2262 (84.7)3108 (86.9)
 60–<901489 (14.4)660 (16.1)383 (14.3)446 (12.5)
 <6077 (0.7)29 (0.7)26 (1.0)22 (0.6)
AHA-PA Categories at ARIC Visit 1OverallRecommendedIntermediatePoorPa
Patients, no.10,342409526713576
METS*min/wkb402.0 (0.0–993.6)1175.9 (874.8–1700.1)339.3 (189.0–489.0)0.0 (0.0–0.0)
Age, y53.8 ± 5.754.1 ± 5.753.7 ± 5.753.5 ± 5.6<0.001
25(OH)D, ng/mLc,d24.7 ± 8.526.6 ± 8.324.4 ± 8.222.7 ± 8.3<0.001
Vitamin D supplement usee3279 (31.7)1440 (35.2)891 (33.4)948 (26.5)<0.001
Total cholesterol, mg/dLc214.3 ± 40.9213.2 ± 39.4214.9 ± 41.6215.0 ± 42.00.11
HDL, mg/dLc52.6 ± 16.953.2 ± 17.352.4 ± 16.252.0 ± 17.1<0.001
LDL, mg/dLc136.7 ± 38.3135.6 ± 37.4137.4 ± 38.5137.4 ± 39.10.06
Triglycerides, mg/dLc127.4 ± 84.1124.3 ± 80.2128.1 ± 82.3130.5 ± 89.60.01
BMI, kg/m227.4 ± 5.126.6 ± 4.427.1 ± 5.028.4 ± 5.7<0.001
Men4396 (42.5)1962 (47.9)1025 (38.4)1409 (39.4)<0.001
Center/race<0.001
 Minneapolis, MN/white2963 (28.7)1423 (34.7)817 (30.6)723 (20.2)
 Washington Co., MD/white2770 (26.8)1095 (26.7)730 (27.3)945 (26.4)
 Forsyth Co., NC/white2468 (23.9)1103 (26.9)649 (24.3)716 (20.0)
 Forsyth Co., NC/black241 (2.3)82 (2.0)88 (3.3)71 (2.0)
 Jackson, MI/black1900 (18.4)392 (9.6)387 (14.5)1121 (31.3)
Education<0.001
 < High school1898 (18.4)478 (11.7)424 (15.9)996 (27.9)
 High school or vocational school4401 (42.6)1669 (40.8)1180 (44.2)1552 (43.4)
 College, graduate, or professional school4043 (39.1)1948 (47.6)1067 (39.9)1028 (28.7)
Smoking status<0.001
 Never4720 (45.6)1861 (45.4)1275 (47.7)1584 (44.3)
 Former3353 (32.4)1499 (36.6)831 (31.1)1023 (28.6)
 Current2269 (21.9)735 (17.9)565 (21.2)969 (27.1)
Current alcohol consumption6114 (59.1)2733 (66.7)1607 (60.2)1774 (49.6)<0.001
Diabetes890 (8.6)282 (6.9)221 (8.3)387 (10.8)<0.001
SBP, mm Hg119.5 ± 17.4118.2 ± 16.8118.7 ± 17.0121.5 ± 18.0<0.001
Hypertension2970 (28.8)1013 (24.8)732 (27.5)1225 (34.4)<0.001
AST, U/Lb,d20.0 (17.0–23.0)20.0 (17.0–23.0)20.0 (17.0–23.0)19.0 (16.0–23.0)<0.001
ALT, U/Lb,d15.0 (11.0–19.0)15.0 (11.0–19.0)15.0 (11.0–19.0)14.0 (11.0–19.0)0.05
GGT, U/Lb,d20.0 (14.0–32.0)20.0 (14.0–30.0)20.0 (14.0–31.0)22.0 (15.0–34.0)<0.001
eGFR, mL/min/1.73 m2<0.001
 ≥908776 (84.9)3406 (83.2)2262 (84.7)3108 (86.9)
 60–<901489 (14.4)660 (16.1)383 (14.3)446 (12.5)
 <6077 (0.7)29 (0.7)26 (1.0)22 (0.6)

Data are given as mean ± standard deviation or number (%) unless otherwise noted.

Abbreviations: ALT, alanine aminotransferase; AST, aspartate aminotransferase; Co., County; GGT, gamma-glutamyl transferase.

a

P value comparing trend of characteristics across the PA categories of Recommended, Intermediate, and Poor.

b

Median (25th to 75th percentile).

c

To convert 25(OH)D levels to nmol/L from ng/mL, multiply by 2.496. To convert the units of measure of total cholesterol, HDL-C, and LDL-C to mmol/L from mg/dL, divide by 38.67. To convert the unit of measure of triglyceride to mmol/L from mg/dL, divide by 88.57.

d

From ARIC visit 2 (1990 to 1992).

e

From ARIC visit 3 (1993 to 1995).

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