Mean, Basal, and GnRH-Stimulated (±SEM) LH Concentrations (Nanograms per Milliliter) in GDX Wild-Type, Heterozygous, and Homozygous GNR23 Mice
| . | n . | Basal LH . | Mean LH . | GnRH Stimulation . | |
|---|---|---|---|---|---|
| Before . | After . | ||||
| Wild type | 7 | 3.43 ± 0.16 | 4.68 ± 0.18 | 3.81 ± 0.36 | 5.60 ± 0.63d |
| Heterozygous | 7 | 2.32 ± 0.28b | 3.35 ± 0.43a | 1.90 ± 0.32 | 4.23 ± 0.31e |
| Homozygous | 6 | 0.82 ± 0.12c | 1.05 ± 0.14c | 0.65 ± 0.23 | 3.05 ± 0.49e |
| . | n . | Basal LH . | Mean LH . | GnRH Stimulation . | |
|---|---|---|---|---|---|
| Before . | After . | ||||
| Wild type | 7 | 3.43 ± 0.16 | 4.68 ± 0.18 | 3.81 ± 0.36 | 5.60 ± 0.63d |
| Heterozygous | 7 | 2.32 ± 0.28b | 3.35 ± 0.43a | 1.90 ± 0.32 | 4.23 ± 0.31e |
| Homozygous | 6 | 0.82 ± 0.12c | 1.05 ± 0.14c | 0.65 ± 0.23 | 3.05 ± 0.49e |
P < .05 compared with wild type (one way ANOVA with Tukey’s multiple comparison).
P < .01 compared with wild type (one way ANOVA with Tukey’s multiple comparison).
P < .001 compared wild type (one way ANOVA with Tukey’s multiple comparison).
P < .05 compared with “Before” (paired t test).
P < .01 compared with “After” (paired t test).
Mean, Basal, and GnRH-Stimulated (±SEM) LH Concentrations (Nanograms per Milliliter) in GDX Wild-Type, Heterozygous, and Homozygous GNR23 Mice
| . | n . | Basal LH . | Mean LH . | GnRH Stimulation . | |
|---|---|---|---|---|---|
| Before . | After . | ||||
| Wild type | 7 | 3.43 ± 0.16 | 4.68 ± 0.18 | 3.81 ± 0.36 | 5.60 ± 0.63d |
| Heterozygous | 7 | 2.32 ± 0.28b | 3.35 ± 0.43a | 1.90 ± 0.32 | 4.23 ± 0.31e |
| Homozygous | 6 | 0.82 ± 0.12c | 1.05 ± 0.14c | 0.65 ± 0.23 | 3.05 ± 0.49e |
| . | n . | Basal LH . | Mean LH . | GnRH Stimulation . | |
|---|---|---|---|---|---|
| Before . | After . | ||||
| Wild type | 7 | 3.43 ± 0.16 | 4.68 ± 0.18 | 3.81 ± 0.36 | 5.60 ± 0.63d |
| Heterozygous | 7 | 2.32 ± 0.28b | 3.35 ± 0.43a | 1.90 ± 0.32 | 4.23 ± 0.31e |
| Homozygous | 6 | 0.82 ± 0.12c | 1.05 ± 0.14c | 0.65 ± 0.23 | 3.05 ± 0.49e |
P < .05 compared with wild type (one way ANOVA with Tukey’s multiple comparison).
P < .01 compared with wild type (one way ANOVA with Tukey’s multiple comparison).
P < .001 compared wild type (one way ANOVA with Tukey’s multiple comparison).
P < .05 compared with “Before” (paired t test).
P < .01 compared with “After” (paired t test).
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