Table 1
Open in new tab

Individual Gene Transcripts Down-Regulated in Astro-D2KO Hippocampus

Gene SymbolDescriptionFoldP Value
Dio2Deiodinase, iodothyronine, type II2.78.000 099
Snord42aSmall nucleolar RNA, C/D box 42A1.82.036 107
Snord61Small nucleolar RNA, C/D box 611.54.005 067
Mir1224microRNA 1224; von Willebrand factor A domain containing 5B21.49.033 586
Cyp1b1Cytochrome P450, family 1, subfamily b, polypeptide 11.46.033 156
Olfr344Olfactory receptor 3441.46.035 988
Snord110Small nucleolar RNA, C/D box 1101.46.013 684
LumLumican1.45.027 892
Ighv10–1Ig heavy variable 10-11.41.021 021
Snord69Small nucleolar RNA, C/D box 691.41.013 871
Mir5127microRNA 51271.41.039 012
Snord49bSmall nucleolar RNA, C/D box 49B1.38.026 267
Ddit4DNA-damage-inducible transcript 41.37.010 851
Ighj2Ig heavy joining 21.37.030 082
Snord55Small nucleolar RNA, C/D box 551.37.030 719
Cyp2j6Cytochrome P450, family 2, subfamily j, polypeptide 61.36.024 732
Ankrd34cAnkyrin repeat domain 34C1.36.023 905
Phlda2Pleckstrin homology-like domain, family A, member 21.35.03 254
Rhox3fReproductive homeobox 3F1.34.017 248
Vmn1r120Vomeronasal 1 receptor 1201.33.025 518
Phf1PHD finger protein 11.32.047 541
Myom1Myomesin 11.32.004 866
Snord16aSmall nucleolar RNA, C/D box 16A1.32.011 198
Snord49aSmall nucleolar RNA, C/D box 49A1.31.045 041
Cyth3Cytohesin 31.31.031 086
Tuba3aTubulin, α3A; tubulin, α3B1.31.044 086
Mageb1Melanoma antigen, family B, 1; melanoma antigen, family B, 21.31.006 397
Olfr1394Olfactory receptor 13941.3.029 162
Lrrc16aLeucine-rich repeat containing 16A1.3.046 377
Klf15Kruppel-like factor 151.3.037 873
Gene SymbolDescriptionFoldP Value
Dio2Deiodinase, iodothyronine, type II2.78.000 099
Snord42aSmall nucleolar RNA, C/D box 42A1.82.036 107
Snord61Small nucleolar RNA, C/D box 611.54.005 067
Mir1224microRNA 1224; von Willebrand factor A domain containing 5B21.49.033 586
Cyp1b1Cytochrome P450, family 1, subfamily b, polypeptide 11.46.033 156
Olfr344Olfactory receptor 3441.46.035 988
Snord110Small nucleolar RNA, C/D box 1101.46.013 684
LumLumican1.45.027 892
Ighv10–1Ig heavy variable 10-11.41.021 021
Snord69Small nucleolar RNA, C/D box 691.41.013 871
Mir5127microRNA 51271.41.039 012
Snord49bSmall nucleolar RNA, C/D box 49B1.38.026 267
Ddit4DNA-damage-inducible transcript 41.37.010 851
Ighj2Ig heavy joining 21.37.030 082
Snord55Small nucleolar RNA, C/D box 551.37.030 719
Cyp2j6Cytochrome P450, family 2, subfamily j, polypeptide 61.36.024 732
Ankrd34cAnkyrin repeat domain 34C1.36.023 905
Phlda2Pleckstrin homology-like domain, family A, member 21.35.03 254
Rhox3fReproductive homeobox 3F1.34.017 248
Vmn1r120Vomeronasal 1 receptor 1201.33.025 518
Phf1PHD finger protein 11.32.047 541
Myom1Myomesin 11.32.004 866
Snord16aSmall nucleolar RNA, C/D box 16A1.32.011 198
Snord49aSmall nucleolar RNA, C/D box 49A1.31.045 041
Cyth3Cytohesin 31.31.031 086
Tuba3aTubulin, α3A; tubulin, α3B1.31.044 086
Mageb1Melanoma antigen, family B, 1; melanoma antigen, family B, 21.31.006 397
Olfr1394Olfactory receptor 13941.3.029 162
Lrrc16aLeucine-rich repeat containing 16A1.3.046 377
Klf15Kruppel-like factor 151.3.037 873

Data were analyzed using Affymetrix Transcriptome Analysis Console (Astro-D2KO, n = 4; control, n = 4) at a value of P < .05 and a fold change of 1.3 or greater or −1.3 or less in the differential analysis of the microarray data from Cre vs Astro-D2KO hippocampus.

Table 1
Open in new tab

Individual Gene Transcripts Down-Regulated in Astro-D2KO Hippocampus

Gene SymbolDescriptionFoldP Value
Dio2Deiodinase, iodothyronine, type II2.78.000 099
Snord42aSmall nucleolar RNA, C/D box 42A1.82.036 107
Snord61Small nucleolar RNA, C/D box 611.54.005 067
Mir1224microRNA 1224; von Willebrand factor A domain containing 5B21.49.033 586
Cyp1b1Cytochrome P450, family 1, subfamily b, polypeptide 11.46.033 156
Olfr344Olfactory receptor 3441.46.035 988
Snord110Small nucleolar RNA, C/D box 1101.46.013 684
LumLumican1.45.027 892
Ighv10–1Ig heavy variable 10-11.41.021 021
Snord69Small nucleolar RNA, C/D box 691.41.013 871
Mir5127microRNA 51271.41.039 012
Snord49bSmall nucleolar RNA, C/D box 49B1.38.026 267
Ddit4DNA-damage-inducible transcript 41.37.010 851
Ighj2Ig heavy joining 21.37.030 082
Snord55Small nucleolar RNA, C/D box 551.37.030 719
Cyp2j6Cytochrome P450, family 2, subfamily j, polypeptide 61.36.024 732
Ankrd34cAnkyrin repeat domain 34C1.36.023 905
Phlda2Pleckstrin homology-like domain, family A, member 21.35.03 254
Rhox3fReproductive homeobox 3F1.34.017 248
Vmn1r120Vomeronasal 1 receptor 1201.33.025 518
Phf1PHD finger protein 11.32.047 541
Myom1Myomesin 11.32.004 866
Snord16aSmall nucleolar RNA, C/D box 16A1.32.011 198
Snord49aSmall nucleolar RNA, C/D box 49A1.31.045 041
Cyth3Cytohesin 31.31.031 086
Tuba3aTubulin, α3A; tubulin, α3B1.31.044 086
Mageb1Melanoma antigen, family B, 1; melanoma antigen, family B, 21.31.006 397
Olfr1394Olfactory receptor 13941.3.029 162
Lrrc16aLeucine-rich repeat containing 16A1.3.046 377
Klf15Kruppel-like factor 151.3.037 873
Gene SymbolDescriptionFoldP Value
Dio2Deiodinase, iodothyronine, type II2.78.000 099
Snord42aSmall nucleolar RNA, C/D box 42A1.82.036 107
Snord61Small nucleolar RNA, C/D box 611.54.005 067
Mir1224microRNA 1224; von Willebrand factor A domain containing 5B21.49.033 586
Cyp1b1Cytochrome P450, family 1, subfamily b, polypeptide 11.46.033 156
Olfr344Olfactory receptor 3441.46.035 988
Snord110Small nucleolar RNA, C/D box 1101.46.013 684
LumLumican1.45.027 892
Ighv10–1Ig heavy variable 10-11.41.021 021
Snord69Small nucleolar RNA, C/D box 691.41.013 871
Mir5127microRNA 51271.41.039 012
Snord49bSmall nucleolar RNA, C/D box 49B1.38.026 267
Ddit4DNA-damage-inducible transcript 41.37.010 851
Ighj2Ig heavy joining 21.37.030 082
Snord55Small nucleolar RNA, C/D box 551.37.030 719
Cyp2j6Cytochrome P450, family 2, subfamily j, polypeptide 61.36.024 732
Ankrd34cAnkyrin repeat domain 34C1.36.023 905
Phlda2Pleckstrin homology-like domain, family A, member 21.35.03 254
Rhox3fReproductive homeobox 3F1.34.017 248
Vmn1r120Vomeronasal 1 receptor 1201.33.025 518
Phf1PHD finger protein 11.32.047 541
Myom1Myomesin 11.32.004 866
Snord16aSmall nucleolar RNA, C/D box 16A1.32.011 198
Snord49aSmall nucleolar RNA, C/D box 49A1.31.045 041
Cyth3Cytohesin 31.31.031 086
Tuba3aTubulin, α3A; tubulin, α3B1.31.044 086
Mageb1Melanoma antigen, family B, 1; melanoma antigen, family B, 21.31.006 397
Olfr1394Olfactory receptor 13941.3.029 162
Lrrc16aLeucine-rich repeat containing 16A1.3.046 377
Klf15Kruppel-like factor 151.3.037 873

Data were analyzed using Affymetrix Transcriptome Analysis Console (Astro-D2KO, n = 4; control, n = 4) at a value of P < .05 and a fold change of 1.3 or greater or −1.3 or less in the differential analysis of the microarray data from Cre vs Astro-D2KO hippocampus.

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