Percent Change in 25-Hydroxy Vitamin D Concentrations (ng/ml) for Use of an Estrogen-Containing Contraception and Use of Vitamin D-Containing Supplement
| . | % Differencea . | 95% Lower Limit . | 95% Upper Limit . |
|---|---|---|---|
| Use of estrogen-containing contraceptionb | 20.0 | 13.8 | 26.5 |
| Use of supplementc | |||
| Low dosed | 14.2 | 7.8 | 20.9 |
| Intermediate dosee | 46.0 | 38.2 | 54.2 |
| High dosef | 76.6 | 59.7 | 95.2 |
| . | % Differencea . | 95% Lower Limit . | 95% Upper Limit . |
|---|---|---|---|
| Use of estrogen-containing contraceptionb | 20.0 | 13.8 | 26.5 |
| Use of supplementc | |||
| Low dosed | 14.2 | 7.8 | 20.9 |
| Intermediate dosee | 46.0 | 38.2 | 54.2 |
| High dosef | 76.6 | 59.7 | 95.2 |
Adjusted model includes all variables in Table 2 plus sine/cosine for first and second harmonics, current BMI >35 kg/m2, smoking with interactions with the first harmonic, indicator for very low D intake with interactions with first harmonic, college education, interaction between smoking and first harmonic, continuous melanin, and quartiles of dietary vitamin D intake and parity. We provide β estimates for all variables (Supplemental Table 1).
Estrogen containing contraception includes: combination birth control pills, contraceptive patch, or vaginal ring.
Supplement use based on highest reported dose/frequency on Food Frequency Questionnaire, or questionnaire at time of blood draw about use within either last 24 h (regular use) or past 4 weeks (irregular use).
Low-dose supplement: vitamin D content < = 200 IU/d or self-report of using single supplement irregularly.
Intermediate-dose supplement: vitamin D content 201–600 IU/d or using multiple supplements irregularly or a single supplement regularly.
High-dose supplement: vitamin D content 601+ IU/day or using multiple supplements daily.
Percent Change in 25-Hydroxy Vitamin D Concentrations (ng/ml) for Use of an Estrogen-Containing Contraception and Use of Vitamin D-Containing Supplement
| . | % Differencea . | 95% Lower Limit . | 95% Upper Limit . |
|---|---|---|---|
| Use of estrogen-containing contraceptionb | 20.0 | 13.8 | 26.5 |
| Use of supplementc | |||
| Low dosed | 14.2 | 7.8 | 20.9 |
| Intermediate dosee | 46.0 | 38.2 | 54.2 |
| High dosef | 76.6 | 59.7 | 95.2 |
| . | % Differencea . | 95% Lower Limit . | 95% Upper Limit . |
|---|---|---|---|
| Use of estrogen-containing contraceptionb | 20.0 | 13.8 | 26.5 |
| Use of supplementc | |||
| Low dosed | 14.2 | 7.8 | 20.9 |
| Intermediate dosee | 46.0 | 38.2 | 54.2 |
| High dosef | 76.6 | 59.7 | 95.2 |
Adjusted model includes all variables in Table 2 plus sine/cosine for first and second harmonics, current BMI >35 kg/m2, smoking with interactions with the first harmonic, indicator for very low D intake with interactions with first harmonic, college education, interaction between smoking and first harmonic, continuous melanin, and quartiles of dietary vitamin D intake and parity. We provide β estimates for all variables (Supplemental Table 1).
Estrogen containing contraception includes: combination birth control pills, contraceptive patch, or vaginal ring.
Supplement use based on highest reported dose/frequency on Food Frequency Questionnaire, or questionnaire at time of blood draw about use within either last 24 h (regular use) or past 4 weeks (irregular use).
Low-dose supplement: vitamin D content < = 200 IU/d or self-report of using single supplement irregularly.
Intermediate-dose supplement: vitamin D content 201–600 IU/d or using multiple supplements irregularly or a single supplement regularly.
High-dose supplement: vitamin D content 601+ IU/day or using multiple supplements daily.
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