Table 1.

Baseline Clinical Characteristics of the Study Patients

CharacteristicsSIM (n = 337)EZ-SIM (n = 564)ATOR (n = 1510)P
Age (y)67.3 ± 11.565.4 ± 10.9a66.2 ± 11.0.047
Age ≥75 years101 (30.0)120 (21.3)a373 (24.7).014
Sex.870
    Male192 (57.0)312 (55.3)838 (55.5)
    Female145 (43.0)252 (44.7)672 (44.5)
Previous MI8 (2.4)15 (2.7)27 (1.8).425
Previous cerebral vascular accident
    Anyc104 (30.9)130 (23.0)a344 (22.8)a.006
    Ischemic81 (24.0)104 (18.4)254 (16.8)a.008
    Hemorrhage10 (3.0)15 (2.7)38 (2.5).893
    Unspecified48 (14.2)57 (10.1)152 (10.1).071
Comorbidity
    Neuropathy64 (19.0)91 (16.1)155 (10.3)a,b<.001
    Retinopathy17 (5.0)32 (5.7)63 (4.2).328
    CAD47 (13.9)68 (12.1)170 (11.3).377
    Chronic kidney disease13 (3.9)15 (2.7)40 (2.6).464
    Chronic obstructive pulmonary disease49 (14.5)57 (10.1)168 (11.1).114
    AF22 (6.5)16 (2.8)a110 (7.3)b.001
    Peripheral arterial disease37 (11.0)46 (8.2)84 (5.6)a.001
    Hypertension304 (90.2)478 (84.8)1283 (85.0)a.036
    Heart failure26 (7.7)26 (4.6)102 (6.8).116
    Malignancy13 (3.9)23 (4.1)68 (4.5).828
    Cirrhosis5 (1.5)0 (0.0)a13 (0.9).031
Previous PCI2 (0.6)4 (0.7)16 (1.1).607
Previous carotid stenting0 (0.0)0 (0.0)2 (0.1).550
CharacteristicsSIM (n = 337)EZ-SIM (n = 564)ATOR (n = 1510)P
Age (y)67.3 ± 11.565.4 ± 10.9a66.2 ± 11.0.047
Age ≥75 years101 (30.0)120 (21.3)a373 (24.7).014
Sex.870
    Male192 (57.0)312 (55.3)838 (55.5)
    Female145 (43.0)252 (44.7)672 (44.5)
Previous MI8 (2.4)15 (2.7)27 (1.8).425
Previous cerebral vascular accident
    Anyc104 (30.9)130 (23.0)a344 (22.8)a.006
    Ischemic81 (24.0)104 (18.4)254 (16.8)a.008
    Hemorrhage10 (3.0)15 (2.7)38 (2.5).893
    Unspecified48 (14.2)57 (10.1)152 (10.1).071
Comorbidity
    Neuropathy64 (19.0)91 (16.1)155 (10.3)a,b<.001
    Retinopathy17 (5.0)32 (5.7)63 (4.2).328
    CAD47 (13.9)68 (12.1)170 (11.3).377
    Chronic kidney disease13 (3.9)15 (2.7)40 (2.6).464
    Chronic obstructive pulmonary disease49 (14.5)57 (10.1)168 (11.1).114
    AF22 (6.5)16 (2.8)a110 (7.3)b.001
    Peripheral arterial disease37 (11.0)46 (8.2)84 (5.6)a.001
    Hypertension304 (90.2)478 (84.8)1283 (85.0)a.036
    Heart failure26 (7.7)26 (4.6)102 (6.8).116
    Malignancy13 (3.9)23 (4.1)68 (4.5).828
    Cirrhosis5 (1.5)0 (0.0)a13 (0.9).031
Previous PCI2 (0.6)4 (0.7)16 (1.1).607
Previous carotid stenting0 (0.0)0 (0.0)2 (0.1).550

Values are the mean ± SD or n (%). PCI, percutaneous coronary intervention.

a

P < .05 vs SIM.

b

P < .05 vs EZ-SIM.

c

One patient might have 2 or more strokes.

Table 1.

Baseline Clinical Characteristics of the Study Patients

CharacteristicsSIM (n = 337)EZ-SIM (n = 564)ATOR (n = 1510)P
Age (y)67.3 ± 11.565.4 ± 10.9a66.2 ± 11.0.047
Age ≥75 years101 (30.0)120 (21.3)a373 (24.7).014
Sex.870
    Male192 (57.0)312 (55.3)838 (55.5)
    Female145 (43.0)252 (44.7)672 (44.5)
Previous MI8 (2.4)15 (2.7)27 (1.8).425
Previous cerebral vascular accident
    Anyc104 (30.9)130 (23.0)a344 (22.8)a.006
    Ischemic81 (24.0)104 (18.4)254 (16.8)a.008
    Hemorrhage10 (3.0)15 (2.7)38 (2.5).893
    Unspecified48 (14.2)57 (10.1)152 (10.1).071
Comorbidity
    Neuropathy64 (19.0)91 (16.1)155 (10.3)a,b<.001
    Retinopathy17 (5.0)32 (5.7)63 (4.2).328
    CAD47 (13.9)68 (12.1)170 (11.3).377
    Chronic kidney disease13 (3.9)15 (2.7)40 (2.6).464
    Chronic obstructive pulmonary disease49 (14.5)57 (10.1)168 (11.1).114
    AF22 (6.5)16 (2.8)a110 (7.3)b.001
    Peripheral arterial disease37 (11.0)46 (8.2)84 (5.6)a.001
    Hypertension304 (90.2)478 (84.8)1283 (85.0)a.036
    Heart failure26 (7.7)26 (4.6)102 (6.8).116
    Malignancy13 (3.9)23 (4.1)68 (4.5).828
    Cirrhosis5 (1.5)0 (0.0)a13 (0.9).031
Previous PCI2 (0.6)4 (0.7)16 (1.1).607
Previous carotid stenting0 (0.0)0 (0.0)2 (0.1).550
CharacteristicsSIM (n = 337)EZ-SIM (n = 564)ATOR (n = 1510)P
Age (y)67.3 ± 11.565.4 ± 10.9a66.2 ± 11.0.047
Age ≥75 years101 (30.0)120 (21.3)a373 (24.7).014
Sex.870
    Male192 (57.0)312 (55.3)838 (55.5)
    Female145 (43.0)252 (44.7)672 (44.5)
Previous MI8 (2.4)15 (2.7)27 (1.8).425
Previous cerebral vascular accident
    Anyc104 (30.9)130 (23.0)a344 (22.8)a.006
    Ischemic81 (24.0)104 (18.4)254 (16.8)a.008
    Hemorrhage10 (3.0)15 (2.7)38 (2.5).893
    Unspecified48 (14.2)57 (10.1)152 (10.1).071
Comorbidity
    Neuropathy64 (19.0)91 (16.1)155 (10.3)a,b<.001
    Retinopathy17 (5.0)32 (5.7)63 (4.2).328
    CAD47 (13.9)68 (12.1)170 (11.3).377
    Chronic kidney disease13 (3.9)15 (2.7)40 (2.6).464
    Chronic obstructive pulmonary disease49 (14.5)57 (10.1)168 (11.1).114
    AF22 (6.5)16 (2.8)a110 (7.3)b.001
    Peripheral arterial disease37 (11.0)46 (8.2)84 (5.6)a.001
    Hypertension304 (90.2)478 (84.8)1283 (85.0)a.036
    Heart failure26 (7.7)26 (4.6)102 (6.8).116
    Malignancy13 (3.9)23 (4.1)68 (4.5).828
    Cirrhosis5 (1.5)0 (0.0)a13 (0.9).031
Previous PCI2 (0.6)4 (0.7)16 (1.1).607
Previous carotid stenting0 (0.0)0 (0.0)2 (0.1).550

Values are the mean ± SD or n (%). PCI, percutaneous coronary intervention.

a

P < .05 vs SIM.

b

P < .05 vs EZ-SIM.

c

One patient might have 2 or more strokes.

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