Table 3. Open in new tab Impact of...

Girls	Thelarche (B2+) Right/Left/Interval Censored (n = 156/175/332)	Pubic Hair (PH2+) Right/Left/Interval Censored (n = 233/115/313)	Age at Menarche Non/Right/Left/Interval Censored (n = 227/357/0/5)
Fathers' puberty
Early^a	−4.1 (−10.6, +2.4)	.217		−7.0 (−12.6, −1.4)	.014		−10.5 (−15.9, 5.1)	<.001
Average^b	2.1 (−3.3, 7.5)	.400	490	0.3 (−4.3, 5.0)	.890	491	−4.1 (−8.4, 0.2)	<.060	490
Late^c	6.2 (1.5, 11.0)	.011		7.4 (3.3, 11.4)	<.001		6.4 (2.2, 10.6)	.003
Mothers' puberty
Early^a	−6.7 (−11.4, −2.0)	.005		−6.7 (−11.0, −2.5)	.002		−10.1 (−14.3, −6.0)	<.001
Average^b	−1.7 (−6.1, 2.7)	.440	559	−2.0 (−5.9, 1.8)	.300	560	−5.7 (−9.2, −2.2)	.002	559
Late^c	5.0 (1.7, 8.8)	.011		4.7 (1.2, 8.2)	.008		4.5 (0.8, 8.2)	.020
Mothers' menarche age	1.8 (0.7, 2.9)	.002	615	1.0 (−0.0, 2.1)	.061	615	4.4 (3.1, 5.6)	<.001	569

Girls

Thelarche (B2+) Right/Left/Interval Censored (n = 156/175/332)

Pubic Hair (PH2+) Right/Left/Interval Censored (n = 233/115/313)

Age at Menarche Non/Right/Left/Interval Censored (n = 227/357/0/5)

Estimated Difference

P Value

N 663

Estimated Difference

P Value

N 661

Estimated Difference

P Value

N 589

Fathers' puberty

Early^a

−4.1 (−10.6, +2.4)

.217

−7.0 (−12.6, −1.4)

.014

−10.5 (−15.9, 5.1)

<.001

Average^b

2.1 (−3.3, 7.5)

.400

490

0.3 (−4.3, 5.0)

.890

491

−4.1 (−8.4, 0.2)

<.060

490

Late^c

6.2 (1.5, 11.0)

.011

7.4 (3.3, 11.4)

<.001

6.4 (2.2, 10.6)

.003

Mothers' puberty

Early^a

−6.7 (−11.4, −2.0)

.005

−6.7 (−11.0, −2.5)

.002

−10.1 (−14.3, −6.0)

<.001

Average^b

−1.7 (−6.1, 2.7)

.440

559

−2.0 (−5.9, 1.8)

.300

560

−5.7 (−9.2, −2.2)

.002

559

Late^c

5.0 (1.7, 8.8)

.011

4.7 (1.2, 8.2)

.008

4.5 (0.8, 8.2)

.020

Mothers' menarche age

1.8 (0.7, 2.9)

.002

615

1.0 (−0.0, 2.1)

.061

615

4.4 (3.1, 5.6)

<.001

569

Girls	Thelarche (B2+) Right/Left/Interval Censored (n = 156/175/332)	Pubic Hair (PH2+) Right/Left/Interval Censored (n = 233/115/313)	Age at Menarche Non/Right/Left/Interval Censored (n = 227/357/0/5)
Fathers' puberty
Early^a	−4.1 (−10.6, +2.4)	.217		−7.0 (−12.6, −1.4)	.014		−10.5 (−15.9, 5.1)	<.001
Average^b	2.1 (−3.3, 7.5)	.400	490	0.3 (−4.3, 5.0)	.890	491	−4.1 (−8.4, 0.2)	<.060	490
Late^c	6.2 (1.5, 11.0)	.011		7.4 (3.3, 11.4)	<.001		6.4 (2.2, 10.6)	.003
Mothers' puberty
Early^a	−6.7 (−11.4, −2.0)	.005		−6.7 (−11.0, −2.5)	.002		−10.1 (−14.3, −6.0)	<.001
Average^b	−1.7 (−6.1, 2.7)	.440	559	−2.0 (−5.9, 1.8)	.300	560	−5.7 (−9.2, −2.2)	.002	559
Late^c	5.0 (1.7, 8.8)	.011		4.7 (1.2, 8.2)	.008		4.5 (0.8, 8.2)	.020
Mothers' menarche age	1.8 (0.7, 2.9)	.002	615	1.0 (−0.0, 2.1)	.061	615	4.4 (3.1, 5.6)	<.001	569

Table 3.

Open in new tab

Impact of Parental Pubertal Timing on the Onset of Thelarche (B2+), Pubarche (PH2+), and Menarche in Girls

Girls	Thelarche (B2+) Right/Left/Interval Censored (n = 156/175/332)			Pubic Hair (PH2+) Right/Left/Interval Censored (n = 233/115/313)			Age at Menarche Non/Right/Left/Interval Censored (n = 227/357/0/5)
Girls	Estimated Difference	P Value	N 663	Estimated Difference	P Value	N 661	Estimated Difference	P Value	N 589
Fathers' puberty
Early^a	−4.1 (−10.6, +2.4)	.217		−7.0 (−12.6, −1.4)	.014		−10.5 (−15.9, 5.1)	<.001
Average^b	2.1 (−3.3, 7.5)	.400	490	0.3 (−4.3, 5.0)	.890	491	−4.1 (−8.4, 0.2)	<.060	490
Late^c	6.2 (1.5, 11.0)	.011		7.4 (3.3, 11.4)	<.001		6.4 (2.2, 10.6)	.003
Mothers' puberty
Early^a	−6.7 (−11.4, −2.0)	.005		−6.7 (−11.0, −2.5)	.002		−10.1 (−14.3, −6.0)	<.001
Average^b	−1.7 (−6.1, 2.7)	.440	559	−2.0 (−5.9, 1.8)	.300	560	−5.7 (−9.2, −2.2)	.002	559
Late^c	5.0 (1.7, 8.8)	.011		4.7 (1.2, 8.2)	.008		4.5 (0.8, 8.2)	.020
Mothers' menarche age	1.8 (0.7, 2.9)	.002	615	1.0 (−0.0, 2.1)	.061	615	4.4 (3.1, 5.6)	<.001	569

Girls	Thelarche (B2+) Right/Left/Interval Censored (n = 156/175/332)			Pubic Hair (PH2+) Right/Left/Interval Censored (n = 233/115/313)			Age at Menarche Non/Right/Left/Interval Censored (n = 227/357/0/5)
Girls	Estimated Difference	P Value	N 663	Estimated Difference	P Value	N 661	Estimated Difference	P Value	N 589
Fathers' puberty
Early^a	−4.1 (−10.6, +2.4)	.217		−7.0 (−12.6, −1.4)	.014		−10.5 (−15.9, 5.1)	<.001
Average^b	2.1 (−3.3, 7.5)	.400	490	0.3 (−4.3, 5.0)	.890	491	−4.1 (−8.4, 0.2)	<.060	490
Late^c	6.2 (1.5, 11.0)	.011		7.4 (3.3, 11.4)	<.001		6.4 (2.2, 10.6)	.003
Mothers' puberty
Early^a	−6.7 (−11.4, −2.0)	.005		−6.7 (−11.0, −2.5)	.002		−10.1 (−14.3, −6.0)	<.001
Average^b	−1.7 (−6.1, 2.7)	.440	559	−2.0 (−5.9, 1.8)	.300	560	−5.7 (−9.2, −2.2)	.002	559
Late^c	5.0 (1.7, 8.8)	.011		4.7 (1.2, 8.2)	.008		4.5 (0.8, 8.2)	.020
Mothers' menarche age	1.8 (0.7, 2.9)	.002	615	1.0 (−0.0, 2.1)	.061	615	4.4 (3.1, 5.6)	<.001	569

Data are expressed as estimate in months (95% CI).

Compared to late maturing.

Compared to early maturing.

Compared to average maturing.

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