Table 2. Open in new tab Impact of...

Boys	Pubic hair (PH2+), Right/Left/Interval Censored (n = 472/82/275)	Gonadarche (Tvol3+) Right/Left/Interval-Censored (n = 398/87/322)	Genital Stage 2 (G2+) Right/Left/Interval Censored (n = 405/108/311)
Fathers' puberty
Early^a	−11.8 (−16.8, −6.8)	<.001	597	−9.5 (−13.9, −5.1)	<.001	595	−8.6 (−13.9, −3.2)	<.001
Average^b	−5.4 (−9.4, −1.3)	.010	−3.1 (−6.6, 0.5)	.090	−2.9 (−7.3, 1.6)	.203	595
Late^c	6.4 (2.6, 10.3)	<.001	6.4 (3.1, 9.7)	<.001	5.7 (1.6, 9.8)	.006
Mothers' puberty
Early^a	−8.9 (−12.8, −4.9)	<.001		−7.1 (−10.4, −3.7)	<.001		−6.5 (−10.7, −2.4)	.002
Average^b	−1.6 (−5.0, 1.8)	.346	663	0.0 (−2.9, 2.9)	.990	660	1.5 (−2.1, 5.1)	.400	662
Late^c	7.2 (3.9, 10.6)	<.001	7.1 (4.3, 9.9)	<.001	8.0 (4.5, 11.5)	<.001
Mothers' menarche age	2.4 (1.4, 3.5)	<.001	770	2.0 (1.0, 2.9)	<.001	743	1.6 (0.4, 2.7)	.006	767

Boys

Pubic hair (PH2+), Right/Left/Interval Censored (n = 472/82/275)

Gonadarche (Tvol3+) Right/Left/Interval-Censored (n = 398/87/322)

Genital Stage 2 (G2+) Right/Left/Interval Censored (n = 405/108/311)

Estimated Difference

P Value

N 829

Estimated Difference

P Value

N 807

Estimated Difference

P Value

N 824

Fathers' puberty

Early^a

−11.8 (−16.8, −6.8)

<.001

597

−9.5 (−13.9, −5.1)

<.001

595

−8.6 (−13.9, −3.2)

<.001

Average^b

−5.4 (−9.4, −1.3)

.010

−3.1 (−6.6, 0.5)

.090

−2.9 (−7.3, 1.6)

.203

595

Late^c

6.4 (2.6, 10.3)

<.001

6.4 (3.1, 9.7)

<.001

5.7 (1.6, 9.8)

.006

Mothers' puberty

Early^a

−8.9 (−12.8, −4.9)

<.001

−7.1 (−10.4, −3.7)

<.001

−6.5 (−10.7, −2.4)

.002

Average^b

−1.6 (−5.0, 1.8)

.346

663

0.0 (−2.9, 2.9)

.990

660

1.5 (−2.1, 5.1)

.400

662

Late^c

7.2 (3.9, 10.6)

<.001

7.1 (4.3, 9.9)

<.001

8.0 (4.5, 11.5)

<.001

Mothers' menarche age

2.4 (1.4, 3.5)

<.001

770

2.0 (1.0, 2.9)

<.001

743

1.6 (0.4, 2.7)

.006

767

Boys	Pubic hair (PH2+), Right/Left/Interval Censored (n = 472/82/275)	Gonadarche (Tvol3+) Right/Left/Interval-Censored (n = 398/87/322)	Genital Stage 2 (G2+) Right/Left/Interval Censored (n = 405/108/311)
Fathers' puberty
Early^a	−11.8 (−16.8, −6.8)	<.001	597	−9.5 (−13.9, −5.1)	<.001	595	−8.6 (−13.9, −3.2)	<.001
Average^b	−5.4 (−9.4, −1.3)	.010	−3.1 (−6.6, 0.5)	.090	−2.9 (−7.3, 1.6)	.203	595
Late^c	6.4 (2.6, 10.3)	<.001	6.4 (3.1, 9.7)	<.001	5.7 (1.6, 9.8)	.006
Mothers' puberty
Early^a	−8.9 (−12.8, −4.9)	<.001		−7.1 (−10.4, −3.7)	<.001		−6.5 (−10.7, −2.4)	.002
Average^b	−1.6 (−5.0, 1.8)	.346	663	0.0 (−2.9, 2.9)	.990	660	1.5 (−2.1, 5.1)	.400	662
Late^c	7.2 (3.9, 10.6)	<.001	7.1 (4.3, 9.9)	<.001	8.0 (4.5, 11.5)	<.001
Mothers' menarche age	2.4 (1.4, 3.5)	<.001	770	2.0 (1.0, 2.9)	<.001	743	1.6 (0.4, 2.7)	.006	767

Table 2.

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Impact of Parental Pubertal Timing on the Onset of Pubarche (PH2+), Gonadarche (Tvol3+), and Tanner Genital Stage 2 (G2+) in Boys

Boys	Pubic hair (PH2+), Right/Left/Interval Censored (n = 472/82/275)			Gonadarche (Tvol3+) Right/Left/Interval-Censored (n = 398/87/322)			Genital Stage 2 (G2+) Right/Left/Interval Censored (n = 405/108/311)
Boys	Estimated Difference	P Value	N 829	Estimated Difference	P Value	N 807	Estimated Difference	P Value	N 824
Fathers' puberty
Early^a	−11.8 (−16.8, −6.8)	<.001	597	−9.5 (−13.9, −5.1)	<.001	595	−8.6 (−13.9, −3.2)	<.001
Average^b	−5.4 (−9.4, −1.3)	.010		−3.1 (−6.6, 0.5)	.090		−2.9 (−7.3, 1.6)	.203	595
Late^c	6.4 (2.6, 10.3)	<.001		6.4 (3.1, 9.7)	<.001		5.7 (1.6, 9.8)	.006
Mothers' puberty
Early^a	−8.9 (−12.8, −4.9)	<.001		−7.1 (−10.4, −3.7)	<.001		−6.5 (−10.7, −2.4)	.002
Average^b	−1.6 (−5.0, 1.8)	.346	663	0.0 (−2.9, 2.9)	.990	660	1.5 (−2.1, 5.1)	.400	662
Late^c	7.2 (3.9, 10.6)	<.001	663	7.1 (4.3, 9.9)	<.001	660	8.0 (4.5, 11.5)	<.001
Mothers' menarche age	2.4 (1.4, 3.5)	<.001	770	2.0 (1.0, 2.9)	<.001	743	1.6 (0.4, 2.7)	.006	767

Boys	Pubic hair (PH2+), Right/Left/Interval Censored (n = 472/82/275)			Gonadarche (Tvol3+) Right/Left/Interval-Censored (n = 398/87/322)			Genital Stage 2 (G2+) Right/Left/Interval Censored (n = 405/108/311)
Boys	Estimated Difference	P Value	N 829	Estimated Difference	P Value	N 807	Estimated Difference	P Value	N 824
Fathers' puberty
Early^a	−11.8 (−16.8, −6.8)	<.001	597	−9.5 (−13.9, −5.1)	<.001	595	−8.6 (−13.9, −3.2)	<.001
Average^b	−5.4 (−9.4, −1.3)	.010		−3.1 (−6.6, 0.5)	.090		−2.9 (−7.3, 1.6)	.203	595
Late^c	6.4 (2.6, 10.3)	<.001		6.4 (3.1, 9.7)	<.001		5.7 (1.6, 9.8)	.006
Mothers' puberty
Early^a	−8.9 (−12.8, −4.9)	<.001		−7.1 (−10.4, −3.7)	<.001		−6.5 (−10.7, −2.4)	.002
Average^b	−1.6 (−5.0, 1.8)	.346	663	0.0 (−2.9, 2.9)	.990	660	1.5 (−2.1, 5.1)	.400	662
Late^c	7.2 (3.9, 10.6)	<.001	663	7.1 (4.3, 9.9)	<.001	660	8.0 (4.5, 11.5)	<.001
Mothers' menarche age	2.4 (1.4, 3.5)	<.001	770	2.0 (1.0, 2.9)	<.001	743	1.6 (0.4, 2.7)	.006	767

Data are expressed as estimate in months (95% CI). Example: boys with early maturing fathers develop pubic hair 11.8 months earlier than if their fathers were late maturing and 5.4 months earlier than if fathers were average maturing. Boys with late maturing fathers develop pubic hair 6.4 months later than if their father were average maturing. An increase in mothers' menarche age (by 1 year) was associated with 2.2 months later pubic hair development in sons.

Compared to late maturing.

Compared to early maturing.

Compared to average maturing.

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