Characteristics . | Total Cohort . | Mutated . | Wild-Type . | P Valuea . |
---|---|---|---|---|
Number of patients | 98 | 24 | 68 | |
Surgery, %b | 46.9 | 83.3 | 33.8 | <.001 |
Right adrenal weight, gc | 36 [6–86] | 42 [21–65] | 29 [6–86] | .099 |
Left adrenal weight, gc | 50 [9–121] | 65 [26–121] | 37 [9–107] | .007 |
Total weight, gc | 81 [0–331] | 107 [53–187] | 50 [23–166] | .001 |
Right adrenal size, mmd | 32 [9–100] | 45 [10–100] | 29 [9–77] | .019 |
Left adrenal size, mmd | 34 [9–130] | 53 [17–100] | 30 [9–130] | .005 |
Total size, mmd | 66 [28–200] | 98 [33–200] | 59 [28–180] | .003 |
No. of nodules, %d | <.001 | |||
2 or less | 57.0 | 15.8 | 68.9 | |
3 | 12.8 | 5.3 | 14.8 | |
4 | 5.8 | 5.3 | 4.9 | |
5 or more | 24.4 | 73.7 | 11.5 |
Characteristics . | Total Cohort . | Mutated . | Wild-Type . | P Valuea . |
---|---|---|---|---|
Number of patients | 98 | 24 | 68 | |
Surgery, %b | 46.9 | 83.3 | 33.8 | <.001 |
Right adrenal weight, gc | 36 [6–86] | 42 [21–65] | 29 [6–86] | .099 |
Left adrenal weight, gc | 50 [9–121] | 65 [26–121] | 37 [9–107] | .007 |
Total weight, gc | 81 [0–331] | 107 [53–187] | 50 [23–166] | .001 |
Right adrenal size, mmd | 32 [9–100] | 45 [10–100] | 29 [9–77] | .019 |
Left adrenal size, mmd | 34 [9–130] | 53 [17–100] | 30 [9–130] | .005 |
Total size, mmd | 66 [28–200] | 98 [33–200] | 59 [28–180] | .003 |
No. of nodules, %d | <.001 | |||
2 or less | 57.0 | 15.8 | 68.9 | |
3 | 12.8 | 5.3 | 14.8 | |
4 | 5.8 | 5.3 | 4.9 | |
5 or more | 24.4 | 73.7 | 11.5 |
Quantitative variables are presented as means [minimum-maximum].
Comparison of mutated patients vs wild-type patients.
Three patients excluded for the comparison, presenting variants of uncertain significance, underwent surgery.
For right, left, total adrenal weight, respectively, data available for 34, 37 and 30 of the 46 operated patients.
For right, left, total adrenal size and number of nodules, respectively, data available for 83, 81, 81, and 86 patients of the total cohort.
Characteristics . | Total Cohort . | Mutated . | Wild-Type . | P Valuea . |
---|---|---|---|---|
Number of patients | 98 | 24 | 68 | |
Surgery, %b | 46.9 | 83.3 | 33.8 | <.001 |
Right adrenal weight, gc | 36 [6–86] | 42 [21–65] | 29 [6–86] | .099 |
Left adrenal weight, gc | 50 [9–121] | 65 [26–121] | 37 [9–107] | .007 |
Total weight, gc | 81 [0–331] | 107 [53–187] | 50 [23–166] | .001 |
Right adrenal size, mmd | 32 [9–100] | 45 [10–100] | 29 [9–77] | .019 |
Left adrenal size, mmd | 34 [9–130] | 53 [17–100] | 30 [9–130] | .005 |
Total size, mmd | 66 [28–200] | 98 [33–200] | 59 [28–180] | .003 |
No. of nodules, %d | <.001 | |||
2 or less | 57.0 | 15.8 | 68.9 | |
3 | 12.8 | 5.3 | 14.8 | |
4 | 5.8 | 5.3 | 4.9 | |
5 or more | 24.4 | 73.7 | 11.5 |
Characteristics . | Total Cohort . | Mutated . | Wild-Type . | P Valuea . |
---|---|---|---|---|
Number of patients | 98 | 24 | 68 | |
Surgery, %b | 46.9 | 83.3 | 33.8 | <.001 |
Right adrenal weight, gc | 36 [6–86] | 42 [21–65] | 29 [6–86] | .099 |
Left adrenal weight, gc | 50 [9–121] | 65 [26–121] | 37 [9–107] | .007 |
Total weight, gc | 81 [0–331] | 107 [53–187] | 50 [23–166] | .001 |
Right adrenal size, mmd | 32 [9–100] | 45 [10–100] | 29 [9–77] | .019 |
Left adrenal size, mmd | 34 [9–130] | 53 [17–100] | 30 [9–130] | .005 |
Total size, mmd | 66 [28–200] | 98 [33–200] | 59 [28–180] | .003 |
No. of nodules, %d | <.001 | |||
2 or less | 57.0 | 15.8 | 68.9 | |
3 | 12.8 | 5.3 | 14.8 | |
4 | 5.8 | 5.3 | 4.9 | |
5 or more | 24.4 | 73.7 | 11.5 |
Quantitative variables are presented as means [minimum-maximum].
Comparison of mutated patients vs wild-type patients.
Three patients excluded for the comparison, presenting variants of uncertain significance, underwent surgery.
For right, left, total adrenal weight, respectively, data available for 34, 37 and 30 of the 46 operated patients.
For right, left, total adrenal size and number of nodules, respectively, data available for 83, 81, 81, and 86 patients of the total cohort.
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