TSH Secretion Parameters in 20 Offspring From Nonagenarian LLS Participants and 18 Partners Thereof
| . | Offspring (n = 20) . | Partners (n = 18) . | P Value . |
|---|---|---|---|
| Basal secretion, mU/L per 24 h | 34.3 (27.2–43.1) | 18.5 (14.4–23.7) | .001 |
| Pulsatile secretion, mU/L per 24 h | 19.0 (14.0–25.6) | 14.9 (10.8–20.6) | .28 |
| Total secretion, mU/L per 24 h | 54.9 (43.5–69.2) | 34.2 (26.6–44.0) | .008 |
| Pulse number (per 24 h) | 17.3 (15.5–19.3) | 17.7 (15.7–19.9) | .79 |
| Mean pulse mass, mU/L | 1.1 (0.8–1.5) | 0.8 (0.6–1.1) | .22 |
| Fast half-life, min | 21.7 (18.5–25.4) | 21.0 (17.6–24.9) | .77 |
| Slow half-life, min | 74.2 (66.3–83.0) | 81.9 (72.5–92.5) | .24 |
| Mode day, min | 11.5 (8.1–14.9) | 14.4 (10.8–18.1) | .23 |
| Mode night, min | 9.2 (6.8–12.5) | 12.1 (8.7–16.9) | .19 |
| λ (unitless) | 16.2 (14.5–18.1) | 16.3 (14.5–18.4) | .91 |
| γ (unitless) | 2.1 (1.9–2.4) | 2.0 (1.8–2.3) | .62 |
| . | Offspring (n = 20) . | Partners (n = 18) . | P Value . |
|---|---|---|---|
| Basal secretion, mU/L per 24 h | 34.3 (27.2–43.1) | 18.5 (14.4–23.7) | .001 |
| Pulsatile secretion, mU/L per 24 h | 19.0 (14.0–25.6) | 14.9 (10.8–20.6) | .28 |
| Total secretion, mU/L per 24 h | 54.9 (43.5–69.2) | 34.2 (26.6–44.0) | .008 |
| Pulse number (per 24 h) | 17.3 (15.5–19.3) | 17.7 (15.7–19.9) | .79 |
| Mean pulse mass, mU/L | 1.1 (0.8–1.5) | 0.8 (0.6–1.1) | .22 |
| Fast half-life, min | 21.7 (18.5–25.4) | 21.0 (17.6–24.9) | .77 |
| Slow half-life, min | 74.2 (66.3–83.0) | 81.9 (72.5–92.5) | .24 |
| Mode day, min | 11.5 (8.1–14.9) | 14.4 (10.8–18.1) | .23 |
| Mode night, min | 9.2 (6.8–12.5) | 12.1 (8.7–16.9) | .19 |
| λ (unitless) | 16.2 (14.5–18.1) | 16.3 (14.5–18.4) | .91 |
| γ (unitless) | 2.1 (1.9–2.4) | 2.0 (1.8–2.3) | .62 |
Data are shown as mean with 95% confidence interval. Differences between the groups were evaluated with a linear mixed model adjusted for age, sex, and body mass index.
TSH Secretion Parameters in 20 Offspring From Nonagenarian LLS Participants and 18 Partners Thereof
| . | Offspring (n = 20) . | Partners (n = 18) . | P Value . |
|---|---|---|---|
| Basal secretion, mU/L per 24 h | 34.3 (27.2–43.1) | 18.5 (14.4–23.7) | .001 |
| Pulsatile secretion, mU/L per 24 h | 19.0 (14.0–25.6) | 14.9 (10.8–20.6) | .28 |
| Total secretion, mU/L per 24 h | 54.9 (43.5–69.2) | 34.2 (26.6–44.0) | .008 |
| Pulse number (per 24 h) | 17.3 (15.5–19.3) | 17.7 (15.7–19.9) | .79 |
| Mean pulse mass, mU/L | 1.1 (0.8–1.5) | 0.8 (0.6–1.1) | .22 |
| Fast half-life, min | 21.7 (18.5–25.4) | 21.0 (17.6–24.9) | .77 |
| Slow half-life, min | 74.2 (66.3–83.0) | 81.9 (72.5–92.5) | .24 |
| Mode day, min | 11.5 (8.1–14.9) | 14.4 (10.8–18.1) | .23 |
| Mode night, min | 9.2 (6.8–12.5) | 12.1 (8.7–16.9) | .19 |
| λ (unitless) | 16.2 (14.5–18.1) | 16.3 (14.5–18.4) | .91 |
| γ (unitless) | 2.1 (1.9–2.4) | 2.0 (1.8–2.3) | .62 |
| . | Offspring (n = 20) . | Partners (n = 18) . | P Value . |
|---|---|---|---|
| Basal secretion, mU/L per 24 h | 34.3 (27.2–43.1) | 18.5 (14.4–23.7) | .001 |
| Pulsatile secretion, mU/L per 24 h | 19.0 (14.0–25.6) | 14.9 (10.8–20.6) | .28 |
| Total secretion, mU/L per 24 h | 54.9 (43.5–69.2) | 34.2 (26.6–44.0) | .008 |
| Pulse number (per 24 h) | 17.3 (15.5–19.3) | 17.7 (15.7–19.9) | .79 |
| Mean pulse mass, mU/L | 1.1 (0.8–1.5) | 0.8 (0.6–1.1) | .22 |
| Fast half-life, min | 21.7 (18.5–25.4) | 21.0 (17.6–24.9) | .77 |
| Slow half-life, min | 74.2 (66.3–83.0) | 81.9 (72.5–92.5) | .24 |
| Mode day, min | 11.5 (8.1–14.9) | 14.4 (10.8–18.1) | .23 |
| Mode night, min | 9.2 (6.8–12.5) | 12.1 (8.7–16.9) | .19 |
| λ (unitless) | 16.2 (14.5–18.1) | 16.3 (14.5–18.4) | .91 |
| γ (unitless) | 2.1 (1.9–2.4) | 2.0 (1.8–2.3) | .62 |
Data are shown as mean with 95% confidence interval. Differences between the groups were evaluated with a linear mixed model adjusted for age, sex, and body mass index.
This PDF is available to Subscribers Only
View Article Abstract & Purchase OptionsFor full access to this pdf, sign in to an existing account, or purchase an annual subscription.
