Results of Bivariate Association for BMD and AAM for the Six Replicated SNPs
| Traits Pair . | SNP . | Chromosome . | Position . | Gene . | Allele . | Chinese Sample P/MAF . | KCOS P/MAF . | WHI-AA P/MAF . | WHI-HIS P/MAF . | Combined P Value . |
|---|---|---|---|---|---|---|---|---|---|---|
| Spine BMD-AAM | rs10817638 | 9 | 117322542 | ATP6V1G1 | G/A | 1.97E-01/0.41 | 7.65E-02/0.35 | 7.65E-02/0.46 | 8.85E-03/0.36 | 1.71E-05 |
| rs7851259 | 9 | 117325336 | ATP6V1G1 | G/A | 5.18E-02/0.43 | 1.93E-01/0.46 | 1.93E-01/0.50 | 9.01E-02/0.50 | 2.88E-03 | |
| rs10982287 | 9 | 117314215 | ATP6V1G1 | A/G | 2.14E-01/0.42 | 8.23E-02/0.33 | 8.23E-02/0.34 | 1.64E-03/0.45 | 8.68E-06 | |
| rs4979427 | 9 | 117323426 | ATP6V1G1 | C/T | 1.78E-01/0.47 | 1.06E-01/0.29 | 1.06E-01/0.37 | 9.76E-01/0.29 | 3.93E-02 | |
| rs7787082 | 7 | 86994987 | ABCB1 | A/G | 6.38E-05/0.31 | 7.00E-03/0.42 | 6.40E-01/0.54 | 7.28E-01/0.23 | 6.05E-05 | |
| rs1469181 | 2 | 229269825 | T/G | 6.13E-06/0.38 | 3.24E-01/0.16 | 6.52E-02/0.30 | 5.45E-01/0.40 | 1.29E-04 | ||
| Hip BMD-AAM | rs10817638 | 9 | 117322542 | ATP6V1G1 | G/A | 4.90E-07/0.41 | 1.76E-02/0.35 | 1.95E-02/0.46 | 8.37E-03/0.36 | 3.02E-09 |
| rs7851259 | 9 | 117325336 | ATP6V1G1 | G/A | 1.07E-06/0.43 | 4.76E-01/0.46 | 3.18E-02/0.50 | 8.93E-02/0.50 | 1.48E-05 | |
| rs10982287 | 9 | 117314215 | ATP6V1G1 | A/G | 1.28E-05/0.42 | 9.42E-03/0.33 | 2.57E-02/0.34 | 1.52E-03/0.45 | 3.49E-09 | |
| rs4979427 | 9 | 117323426 | ATP6V1G1 | C/T | 5.42E-05/0.47 | 7.65E-01/0.29 | 3.64E-02/0.37 | 9.16E-01/0.29 | 4.56E-04 | |
| rs7787082 | 7 | 86994987 | ABCB1 | A/G | 9.63E-01/0.31 | 1.02E-02/0.42 | 4.61E-01/0.54 | 6.91E-01/0.23 | 2.63E-02 | |
| rs1469181 | 2 | 229269825 | T/G | 1.18E-06/0.38 | 3.04E-02/0.16 | 2.12E-01/0.30 | 5.52E-01/0.40 | 6.81E-06 |
| Traits Pair . | SNP . | Chromosome . | Position . | Gene . | Allele . | Chinese Sample P/MAF . | KCOS P/MAF . | WHI-AA P/MAF . | WHI-HIS P/MAF . | Combined P Value . |
|---|---|---|---|---|---|---|---|---|---|---|
| Spine BMD-AAM | rs10817638 | 9 | 117322542 | ATP6V1G1 | G/A | 1.97E-01/0.41 | 7.65E-02/0.35 | 7.65E-02/0.46 | 8.85E-03/0.36 | 1.71E-05 |
| rs7851259 | 9 | 117325336 | ATP6V1G1 | G/A | 5.18E-02/0.43 | 1.93E-01/0.46 | 1.93E-01/0.50 | 9.01E-02/0.50 | 2.88E-03 | |
| rs10982287 | 9 | 117314215 | ATP6V1G1 | A/G | 2.14E-01/0.42 | 8.23E-02/0.33 | 8.23E-02/0.34 | 1.64E-03/0.45 | 8.68E-06 | |
| rs4979427 | 9 | 117323426 | ATP6V1G1 | C/T | 1.78E-01/0.47 | 1.06E-01/0.29 | 1.06E-01/0.37 | 9.76E-01/0.29 | 3.93E-02 | |
| rs7787082 | 7 | 86994987 | ABCB1 | A/G | 6.38E-05/0.31 | 7.00E-03/0.42 | 6.40E-01/0.54 | 7.28E-01/0.23 | 6.05E-05 | |
| rs1469181 | 2 | 229269825 | T/G | 6.13E-06/0.38 | 3.24E-01/0.16 | 6.52E-02/0.30 | 5.45E-01/0.40 | 1.29E-04 | ||
| Hip BMD-AAM | rs10817638 | 9 | 117322542 | ATP6V1G1 | G/A | 4.90E-07/0.41 | 1.76E-02/0.35 | 1.95E-02/0.46 | 8.37E-03/0.36 | 3.02E-09 |
| rs7851259 | 9 | 117325336 | ATP6V1G1 | G/A | 1.07E-06/0.43 | 4.76E-01/0.46 | 3.18E-02/0.50 | 8.93E-02/0.50 | 1.48E-05 | |
| rs10982287 | 9 | 117314215 | ATP6V1G1 | A/G | 1.28E-05/0.42 | 9.42E-03/0.33 | 2.57E-02/0.34 | 1.52E-03/0.45 | 3.49E-09 | |
| rs4979427 | 9 | 117323426 | ATP6V1G1 | C/T | 5.42E-05/0.47 | 7.65E-01/0.29 | 3.64E-02/0.37 | 9.16E-01/0.29 | 4.56E-04 | |
| rs7787082 | 7 | 86994987 | ABCB1 | A/G | 9.63E-01/0.31 | 1.02E-02/0.42 | 4.61E-01/0.54 | 6.91E-01/0.23 | 2.63E-02 | |
| rs1469181 | 2 | 229269825 | T/G | 1.18E-06/0.38 | 3.04E-02/0.16 | 2.12E-01/0.30 | 5.52E-01/0.40 | 6.81E-06 |
Results of Bivariate Association for BMD and AAM for the Six Replicated SNPs
| Traits Pair . | SNP . | Chromosome . | Position . | Gene . | Allele . | Chinese Sample P/MAF . | KCOS P/MAF . | WHI-AA P/MAF . | WHI-HIS P/MAF . | Combined P Value . |
|---|---|---|---|---|---|---|---|---|---|---|
| Spine BMD-AAM | rs10817638 | 9 | 117322542 | ATP6V1G1 | G/A | 1.97E-01/0.41 | 7.65E-02/0.35 | 7.65E-02/0.46 | 8.85E-03/0.36 | 1.71E-05 |
| rs7851259 | 9 | 117325336 | ATP6V1G1 | G/A | 5.18E-02/0.43 | 1.93E-01/0.46 | 1.93E-01/0.50 | 9.01E-02/0.50 | 2.88E-03 | |
| rs10982287 | 9 | 117314215 | ATP6V1G1 | A/G | 2.14E-01/0.42 | 8.23E-02/0.33 | 8.23E-02/0.34 | 1.64E-03/0.45 | 8.68E-06 | |
| rs4979427 | 9 | 117323426 | ATP6V1G1 | C/T | 1.78E-01/0.47 | 1.06E-01/0.29 | 1.06E-01/0.37 | 9.76E-01/0.29 | 3.93E-02 | |
| rs7787082 | 7 | 86994987 | ABCB1 | A/G | 6.38E-05/0.31 | 7.00E-03/0.42 | 6.40E-01/0.54 | 7.28E-01/0.23 | 6.05E-05 | |
| rs1469181 | 2 | 229269825 | T/G | 6.13E-06/0.38 | 3.24E-01/0.16 | 6.52E-02/0.30 | 5.45E-01/0.40 | 1.29E-04 | ||
| Hip BMD-AAM | rs10817638 | 9 | 117322542 | ATP6V1G1 | G/A | 4.90E-07/0.41 | 1.76E-02/0.35 | 1.95E-02/0.46 | 8.37E-03/0.36 | 3.02E-09 |
| rs7851259 | 9 | 117325336 | ATP6V1G1 | G/A | 1.07E-06/0.43 | 4.76E-01/0.46 | 3.18E-02/0.50 | 8.93E-02/0.50 | 1.48E-05 | |
| rs10982287 | 9 | 117314215 | ATP6V1G1 | A/G | 1.28E-05/0.42 | 9.42E-03/0.33 | 2.57E-02/0.34 | 1.52E-03/0.45 | 3.49E-09 | |
| rs4979427 | 9 | 117323426 | ATP6V1G1 | C/T | 5.42E-05/0.47 | 7.65E-01/0.29 | 3.64E-02/0.37 | 9.16E-01/0.29 | 4.56E-04 | |
| rs7787082 | 7 | 86994987 | ABCB1 | A/G | 9.63E-01/0.31 | 1.02E-02/0.42 | 4.61E-01/0.54 | 6.91E-01/0.23 | 2.63E-02 | |
| rs1469181 | 2 | 229269825 | T/G | 1.18E-06/0.38 | 3.04E-02/0.16 | 2.12E-01/0.30 | 5.52E-01/0.40 | 6.81E-06 |
| Traits Pair . | SNP . | Chromosome . | Position . | Gene . | Allele . | Chinese Sample P/MAF . | KCOS P/MAF . | WHI-AA P/MAF . | WHI-HIS P/MAF . | Combined P Value . |
|---|---|---|---|---|---|---|---|---|---|---|
| Spine BMD-AAM | rs10817638 | 9 | 117322542 | ATP6V1G1 | G/A | 1.97E-01/0.41 | 7.65E-02/0.35 | 7.65E-02/0.46 | 8.85E-03/0.36 | 1.71E-05 |
| rs7851259 | 9 | 117325336 | ATP6V1G1 | G/A | 5.18E-02/0.43 | 1.93E-01/0.46 | 1.93E-01/0.50 | 9.01E-02/0.50 | 2.88E-03 | |
| rs10982287 | 9 | 117314215 | ATP6V1G1 | A/G | 2.14E-01/0.42 | 8.23E-02/0.33 | 8.23E-02/0.34 | 1.64E-03/0.45 | 8.68E-06 | |
| rs4979427 | 9 | 117323426 | ATP6V1G1 | C/T | 1.78E-01/0.47 | 1.06E-01/0.29 | 1.06E-01/0.37 | 9.76E-01/0.29 | 3.93E-02 | |
| rs7787082 | 7 | 86994987 | ABCB1 | A/G | 6.38E-05/0.31 | 7.00E-03/0.42 | 6.40E-01/0.54 | 7.28E-01/0.23 | 6.05E-05 | |
| rs1469181 | 2 | 229269825 | T/G | 6.13E-06/0.38 | 3.24E-01/0.16 | 6.52E-02/0.30 | 5.45E-01/0.40 | 1.29E-04 | ||
| Hip BMD-AAM | rs10817638 | 9 | 117322542 | ATP6V1G1 | G/A | 4.90E-07/0.41 | 1.76E-02/0.35 | 1.95E-02/0.46 | 8.37E-03/0.36 | 3.02E-09 |
| rs7851259 | 9 | 117325336 | ATP6V1G1 | G/A | 1.07E-06/0.43 | 4.76E-01/0.46 | 3.18E-02/0.50 | 8.93E-02/0.50 | 1.48E-05 | |
| rs10982287 | 9 | 117314215 | ATP6V1G1 | A/G | 1.28E-05/0.42 | 9.42E-03/0.33 | 2.57E-02/0.34 | 1.52E-03/0.45 | 3.49E-09 | |
| rs4979427 | 9 | 117323426 | ATP6V1G1 | C/T | 5.42E-05/0.47 | 7.65E-01/0.29 | 3.64E-02/0.37 | 9.16E-01/0.29 | 4.56E-04 | |
| rs7787082 | 7 | 86994987 | ABCB1 | A/G | 9.63E-01/0.31 | 1.02E-02/0.42 | 4.61E-01/0.54 | 6.91E-01/0.23 | 2.63E-02 | |
| rs1469181 | 2 | 229269825 | T/G | 1.18E-06/0.38 | 3.04E-02/0.16 | 2.12E-01/0.30 | 5.52E-01/0.40 | 6.81E-06 |
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