Table 1.
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Association Between PNPLA3I148M Genotype and Hepatic Triglyceride and Retinoid Content

PNPLA3 I148M GenotypeIIIMMMPANOVAPdomPrec
n =23136
Liver triglyceride content (%)2.53 ± 2.363.40 ± 2.613.77 ± 2.47.161.029.253
Retinol (μmol/g protein)0.319 ± 0.1790.369 ± 0.2060.312 ± 0.081.744.449.848
Retinyl-palmitate (μmol/g protein)5.51 ± 4.005.97 ± 3.5710.47 ± 3.35.039.075.016
Retinyl-linoleate (μmol/g protein)0.259 ± 0.3100.229 ± 0.1580.490 ± 0.403.245.619.047
Retinyl-oleate (μmol/g protein)0.460 ± 0.4050.435 ± 0.2891.178 ± 0.448.008.335.001
Retinol/retinyl-palmitate0.089 ± 0.0720.069 ± 0.0380.033 ± 0.018.028.117.008
Retinol/retinyl-linoleate2.346 ± 1.7542.617 ± 1.9671.409 ± 1.878.107.610.038
Retinol/retinyl-oleate1.094 ± 0.8871.126 ± 0.7220.307 ± 0.151.003.357.0006
PNPLA3 I148M GenotypeIIIMMMPANOVAPdomPrec
n =23136
Liver triglyceride content (%)2.53 ± 2.363.40 ± 2.613.77 ± 2.47.161.029.253
Retinol (μmol/g protein)0.319 ± 0.1790.369 ± 0.2060.312 ± 0.081.744.449.848
Retinyl-palmitate (μmol/g protein)5.51 ± 4.005.97 ± 3.5710.47 ± 3.35.039.075.016
Retinyl-linoleate (μmol/g protein)0.259 ± 0.3100.229 ± 0.1580.490 ± 0.403.245.619.047
Retinyl-oleate (μmol/g protein)0.460 ± 0.4050.435 ± 0.2891.178 ± 0.448.008.335.001
Retinol/retinyl-palmitate0.089 ± 0.0720.069 ± 0.0380.033 ± 0.018.028.117.008
Retinol/retinyl-linoleate2.346 ± 1.7542.617 ± 1.9671.409 ± 1.878.107.610.038
Retinol/retinyl-oleate1.094 ± 0.8871.126 ± 0.7220.307 ± 0.151.003.357.0006

Data represent means ± sd. For statistical analysis, data were ln-transformed.

Abbreviations: PANOVA, P values for ANOVA; Prec, P values for the recessive inheritance model; Pdom, P values for the dominant inheritance model.

Table 1.
Open in new tab

Association Between PNPLA3I148M Genotype and Hepatic Triglyceride and Retinoid Content

PNPLA3 I148M GenotypeIIIMMMPANOVAPdomPrec
n =23136
Liver triglyceride content (%)2.53 ± 2.363.40 ± 2.613.77 ± 2.47.161.029.253
Retinol (μmol/g protein)0.319 ± 0.1790.369 ± 0.2060.312 ± 0.081.744.449.848
Retinyl-palmitate (μmol/g protein)5.51 ± 4.005.97 ± 3.5710.47 ± 3.35.039.075.016
Retinyl-linoleate (μmol/g protein)0.259 ± 0.3100.229 ± 0.1580.490 ± 0.403.245.619.047
Retinyl-oleate (μmol/g protein)0.460 ± 0.4050.435 ± 0.2891.178 ± 0.448.008.335.001
Retinol/retinyl-palmitate0.089 ± 0.0720.069 ± 0.0380.033 ± 0.018.028.117.008
Retinol/retinyl-linoleate2.346 ± 1.7542.617 ± 1.9671.409 ± 1.878.107.610.038
Retinol/retinyl-oleate1.094 ± 0.8871.126 ± 0.7220.307 ± 0.151.003.357.0006
PNPLA3 I148M GenotypeIIIMMMPANOVAPdomPrec
n =23136
Liver triglyceride content (%)2.53 ± 2.363.40 ± 2.613.77 ± 2.47.161.029.253
Retinol (μmol/g protein)0.319 ± 0.1790.369 ± 0.2060.312 ± 0.081.744.449.848
Retinyl-palmitate (μmol/g protein)5.51 ± 4.005.97 ± 3.5710.47 ± 3.35.039.075.016
Retinyl-linoleate (μmol/g protein)0.259 ± 0.3100.229 ± 0.1580.490 ± 0.403.245.619.047
Retinyl-oleate (μmol/g protein)0.460 ± 0.4050.435 ± 0.2891.178 ± 0.448.008.335.001
Retinol/retinyl-palmitate0.089 ± 0.0720.069 ± 0.0380.033 ± 0.018.028.117.008
Retinol/retinyl-linoleate2.346 ± 1.7542.617 ± 1.9671.409 ± 1.878.107.610.038
Retinol/retinyl-oleate1.094 ± 0.8871.126 ± 0.7220.307 ± 0.151.003.357.0006

Data represent means ± sd. For statistical analysis, data were ln-transformed.

Abbreviations: PANOVA, P values for ANOVA; Prec, P values for the recessive inheritance model; Pdom, P values for the dominant inheritance model.

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