Table 5: Open in new tab Bleeding...

Table 5:

Open in new tab

Bleeding

Life-threatening or disabling bleeding

Fatal bleeding (BARC type 5) OR
Bleeding in a critical organ, such as intracranial, intraspinal, intraocular, or pericardial necessitating pericardiocentesis, or intramuscular with compartment syndrome (BARC type 3b and 3c) OR
Bleeding causing hypovolaemic shock or severe hypotension requiring vasopressors or surgery (BARC type 3b) OR
Overt source of bleeding with drop in haemoglobin ≥5 g/dl or whole blood or packed red blood cells (RBCs) transfusion ≥4 units^a(BARC type 3b)

Major bleeding (BARC type 3a)

Overt bleeding either associated with a drop in the haemoglobin level of at least 3.0 g/dl or requiring transfusion of two or three units of whole blood/RBC, or causing hospitalization or permanent injury, or requiring surgery AND
Does not meet criteria of life-threatening or disabling bleeding

Minor bleeding (BARC type 2 or 3a, depending on the severity)

Any bleeding worthy of clinical mention (e.g. access site haematoma) that does not qualify as life-threatening, disabling, or major

BARC: Bleeding Academic Research Consortium [29]; RBC, red blood cell.

^aGiven that one unit of packed RBC typically will raise the haemoglobin concentration by 1 g/dl, an estimated decrease in haemoglobin will be calculated.

This Feature Is Available To Subscribers Only