Acid–base and biological variables before drug administration. Sepsis was induced at T0 min. Data at T120 min represent variables before drug administration. Pco2 gap, gradient between arterial and ileal mucosal Pco2. Data are presented as median (inter-quartile range)
| Time (min) . | T0 . | T120 . |
|---|---|---|
| Arterial pH | 7.46 (7.41–7.48) | 7.42 (7.37–7.44) |
| Bicarbonates (mmol litre−1) | 27.5 (26–28) | 27 (26–28) |
| Arterial lactate (mmol litre−1) | 2.53 (2.25–2.89) | 2.89 (2.50–3.48) |
| Mixed venous lactate | 2.48 (2.06–2.72) | 2.44 (2.27–3.10) |
| Portal venous lactate | 2.78 (2.21–3.02) | 2.56 (2.14–3.05) |
| Pco2 gap (Torr) | 18 (14–22) | 22 (13–31) |
| Mixed venous oxygen saturation (Svmo2) (%) | 83 (77–86) | 79 (69–87) |
| Haemoglobin (g litre−1) | 89 (86–98) | 93 (87–96) |
| Time (min) . | T0 . | T120 . |
|---|---|---|
| Arterial pH | 7.46 (7.41–7.48) | 7.42 (7.37–7.44) |
| Bicarbonates (mmol litre−1) | 27.5 (26–28) | 27 (26–28) |
| Arterial lactate (mmol litre−1) | 2.53 (2.25–2.89) | 2.89 (2.50–3.48) |
| Mixed venous lactate | 2.48 (2.06–2.72) | 2.44 (2.27–3.10) |
| Portal venous lactate | 2.78 (2.21–3.02) | 2.56 (2.14–3.05) |
| Pco2 gap (Torr) | 18 (14–22) | 22 (13–31) |
| Mixed venous oxygen saturation (Svmo2) (%) | 83 (77–86) | 79 (69–87) |
| Haemoglobin (g litre−1) | 89 (86–98) | 93 (87–96) |
Acid–base and biological variables before drug administration. Sepsis was induced at T0 min. Data at T120 min represent variables before drug administration. Pco2 gap, gradient between arterial and ileal mucosal Pco2. Data are presented as median (inter-quartile range)
| Time (min) . | T0 . | T120 . |
|---|---|---|
| Arterial pH | 7.46 (7.41–7.48) | 7.42 (7.37–7.44) |
| Bicarbonates (mmol litre−1) | 27.5 (26–28) | 27 (26–28) |
| Arterial lactate (mmol litre−1) | 2.53 (2.25–2.89) | 2.89 (2.50–3.48) |
| Mixed venous lactate | 2.48 (2.06–2.72) | 2.44 (2.27–3.10) |
| Portal venous lactate | 2.78 (2.21–3.02) | 2.56 (2.14–3.05) |
| Pco2 gap (Torr) | 18 (14–22) | 22 (13–31) |
| Mixed venous oxygen saturation (Svmo2) (%) | 83 (77–86) | 79 (69–87) |
| Haemoglobin (g litre−1) | 89 (86–98) | 93 (87–96) |
| Time (min) . | T0 . | T120 . |
|---|---|---|
| Arterial pH | 7.46 (7.41–7.48) | 7.42 (7.37–7.44) |
| Bicarbonates (mmol litre−1) | 27.5 (26–28) | 27 (26–28) |
| Arterial lactate (mmol litre−1) | 2.53 (2.25–2.89) | 2.89 (2.50–3.48) |
| Mixed venous lactate | 2.48 (2.06–2.72) | 2.44 (2.27–3.10) |
| Portal venous lactate | 2.78 (2.21–3.02) | 2.56 (2.14–3.05) |
| Pco2 gap (Torr) | 18 (14–22) | 22 (13–31) |
| Mixed venous oxygen saturation (Svmo2) (%) | 83 (77–86) | 79 (69–87) |
| Haemoglobin (g litre−1) | 89 (86–98) | 93 (87–96) |
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