Table 1. Open in new tab Baseline...

	+/+	−/−
Blood glucose (mg/dl)
Fasted	102 ± 10 (19)	91 ± 15 (19)^a
Fed	145 ± 18 (21)	103 ± 10 (27)
Insulin (ng/ml)
Fasted	1.8 ± 1.2 (19)	1.1 ± 0.6 (32)^b
Fed	2.4 ± 1.5 (19)	1.3 ± 0.8 (32)^b
Glucagon (pg/ml)
Fasted	41 ± 12 (18)	62 ± 15 (19)
Fed	75 ± 39 (21)	130 ± 64 (33)^b
Leptin (ng/ml)
Fasted	1.7 ± 1.0 (19)	4.4 ± 2.6 (37)
Fed	4.4 ± 2.1 (19)	5.2 ± 2.4 (37)
Cholesterol (mg/dl)
Fasted	147 ± 28 (44)	140 ± 33 (41)
Fed	ND	ND
Triglycerides (mg/dl)
Fasted	133 ± 25 (19)	153 ± 47 (25)
Fed	190 ± 42 (34)	205 ± 51 (66)
Free fatty acids (mmol/liter)
Fasted	0.9 ± 0.4 (19)	1.2 ± 0.3 (19)
Fed	1.7 ± 0.3 (24)	2.0 ± 0.5 (43)

	+/+	−/−
Blood glucose (mg/dl)
Fasted	102 ± 10 (19)	91 ± 15 (19)^a
Fed	145 ± 18 (21)	103 ± 10 (27)
Insulin (ng/ml)
Fasted	1.8 ± 1.2 (19)	1.1 ± 0.6 (32)^b
Fed	2.4 ± 1.5 (19)	1.3 ± 0.8 (32)^b
Glucagon (pg/ml)
Fasted	41 ± 12 (18)	62 ± 15 (19)
Fed	75 ± 39 (21)	130 ± 64 (33)^b
Leptin (ng/ml)
Fasted	1.7 ± 1.0 (19)	4.4 ± 2.6 (37)
Fed	4.4 ± 2.1 (19)	5.2 ± 2.4 (37)
Cholesterol (mg/dl)
Fasted	147 ± 28 (44)	140 ± 33 (41)
Fed	ND	ND
Triglycerides (mg/dl)
Fasted	133 ± 25 (19)	153 ± 47 (25)
Fed	190 ± 42 (34)	205 ± 51 (66)
Free fatty acids (mmol/liter)
Fasted	0.9 ± 0.4 (19)	1.2 ± 0.3 (19)
Fed	1.7 ± 0.3 (24)	2.0 ± 0.5 (43)

Table 1.

Baseline Metabolic Parameters of WT (+/+) and sst₅ KO (−/−) Mice

	+/+	−/−
Blood glucose (mg/dl)
Fasted	102 ± 10 (19)	91 ± 15 (19)^a
Fed	145 ± 18 (21)	103 ± 10 (27)
Insulin (ng/ml)
Fasted	1.8 ± 1.2 (19)	1.1 ± 0.6 (32)^b
Fed	2.4 ± 1.5 (19)	1.3 ± 0.8 (32)^b
Glucagon (pg/ml)
Fasted	41 ± 12 (18)	62 ± 15 (19)
Fed	75 ± 39 (21)	130 ± 64 (33)^b
Leptin (ng/ml)
Fasted	1.7 ± 1.0 (19)	4.4 ± 2.6 (37)
Fed	4.4 ± 2.1 (19)	5.2 ± 2.4 (37)
Cholesterol (mg/dl)
Fasted	147 ± 28 (44)	140 ± 33 (41)
Fed	ND	ND
Triglycerides (mg/dl)
Fasted	133 ± 25 (19)	153 ± 47 (25)
Fed	190 ± 42 (34)	205 ± 51 (66)
Free fatty acids (mmol/liter)
Fasted	0.9 ± 0.4 (19)	1.2 ± 0.3 (19)
Fed	1.7 ± 0.3 (24)	2.0 ± 0.5 (43)

	+/+	−/−
Blood glucose (mg/dl)
Fasted	102 ± 10 (19)	91 ± 15 (19)^a
Fed	145 ± 18 (21)	103 ± 10 (27)
Insulin (ng/ml)
Fasted	1.8 ± 1.2 (19)	1.1 ± 0.6 (32)^b
Fed	2.4 ± 1.5 (19)	1.3 ± 0.8 (32)^b
Glucagon (pg/ml)
Fasted	41 ± 12 (18)	62 ± 15 (19)
Fed	75 ± 39 (21)	130 ± 64 (33)^b
Leptin (ng/ml)
Fasted	1.7 ± 1.0 (19)	4.4 ± 2.6 (37)
Fed	4.4 ± 2.1 (19)	5.2 ± 2.4 (37)
Cholesterol (mg/dl)
Fasted	147 ± 28 (44)	140 ± 33 (41)
Fed	ND	ND
Triglycerides (mg/dl)
Fasted	133 ± 25 (19)	153 ± 47 (25)
Fed	190 ± 42 (34)	205 ± 51 (66)
Free fatty acids (mmol/liter)
Fasted	0.9 ± 0.4 (19)	1.2 ± 0.3 (19)
Fed	1.7 ± 0.3 (24)	2.0 ± 0.5 (43)

Animals were age-matched males 3–6 months old fed ad libitum or fasted for 12–16 h. Values represent mean ± sd. Numbers in parentheses indicate number of animals tested. ND, not done.

P < 0.05;

P < 0.01.

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