Demonstrating the Staining Patterns of HIP1R, Vimentin, and H3K27me3 To Aid in the Differential Diagnosis Between Oligodendrogliomas and Astrocytomas.
| Pattern . | HIP1R . | Vimentin . | H3K27me3 . | Diagnosis . |
|---|---|---|---|---|
| Pattern 1 | Homogenous | Negative/focal positive | Complete loss | Oligodendroglioma |
| Pattern 2 | Homogenous + Mosaic | Negative/focal positive | Complete loss | Oligodendroglioma with cortical infiltration along with fragments of normal white matter or mini-gemistocytes, or reactive astrocytes |
| Pattern 3 | Mosaic | Diffuse/focal positive | Complete loss or partially loss or intact | Astrocytoma or GBM |
| Pattern 4 | Sparse | Diffuse/focal positive | Complete loss or partially loss or intact | Astrocytoma or GBM |
| Pattern 5 | Negative | Diffuse/focal positive | Complete loss or partially loss or intact | Astrocytoma or GBM |
| Pattern 6 | Homogenous + Mosaic | Diffuse/focal positive | Complete losss or partially loss or intact | Astrocytoma or GBM |
| Pattern . | HIP1R . | Vimentin . | H3K27me3 . | Diagnosis . |
|---|---|---|---|---|
| Pattern 1 | Homogenous | Negative/focal positive | Complete loss | Oligodendroglioma |
| Pattern 2 | Homogenous + Mosaic | Negative/focal positive | Complete loss | Oligodendroglioma with cortical infiltration along with fragments of normal white matter or mini-gemistocytes, or reactive astrocytes |
| Pattern 3 | Mosaic | Diffuse/focal positive | Complete loss or partially loss or intact | Astrocytoma or GBM |
| Pattern 4 | Sparse | Diffuse/focal positive | Complete loss or partially loss or intact | Astrocytoma or GBM |
| Pattern 5 | Negative | Diffuse/focal positive | Complete loss or partially loss or intact | Astrocytoma or GBM |
| Pattern 6 | Homogenous + Mosaic | Diffuse/focal positive | Complete losss or partially loss or intact | Astrocytoma or GBM |
Demonstrating the Staining Patterns of HIP1R, Vimentin, and H3K27me3 To Aid in the Differential Diagnosis Between Oligodendrogliomas and Astrocytomas.
| Pattern . | HIP1R . | Vimentin . | H3K27me3 . | Diagnosis . |
|---|---|---|---|---|
| Pattern 1 | Homogenous | Negative/focal positive | Complete loss | Oligodendroglioma |
| Pattern 2 | Homogenous + Mosaic | Negative/focal positive | Complete loss | Oligodendroglioma with cortical infiltration along with fragments of normal white matter or mini-gemistocytes, or reactive astrocytes |
| Pattern 3 | Mosaic | Diffuse/focal positive | Complete loss or partially loss or intact | Astrocytoma or GBM |
| Pattern 4 | Sparse | Diffuse/focal positive | Complete loss or partially loss or intact | Astrocytoma or GBM |
| Pattern 5 | Negative | Diffuse/focal positive | Complete loss or partially loss or intact | Astrocytoma or GBM |
| Pattern 6 | Homogenous + Mosaic | Diffuse/focal positive | Complete losss or partially loss or intact | Astrocytoma or GBM |
| Pattern . | HIP1R . | Vimentin . | H3K27me3 . | Diagnosis . |
|---|---|---|---|---|
| Pattern 1 | Homogenous | Negative/focal positive | Complete loss | Oligodendroglioma |
| Pattern 2 | Homogenous + Mosaic | Negative/focal positive | Complete loss | Oligodendroglioma with cortical infiltration along with fragments of normal white matter or mini-gemistocytes, or reactive astrocytes |
| Pattern 3 | Mosaic | Diffuse/focal positive | Complete loss or partially loss or intact | Astrocytoma or GBM |
| Pattern 4 | Sparse | Diffuse/focal positive | Complete loss or partially loss or intact | Astrocytoma or GBM |
| Pattern 5 | Negative | Diffuse/focal positive | Complete loss or partially loss or intact | Astrocytoma or GBM |
| Pattern 6 | Homogenous + Mosaic | Diffuse/focal positive | Complete losss or partially loss or intact | Astrocytoma or GBM |
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