correlations between T-bet+ B cell populations and the SLEDAI scores of the patients, complement components C3 and C4, ANA and anti-dsDNA autoantibodies and IFNα and TNFα cytokines
| SLEDAI | C3 | C4 | ANA titers | Anti- dsDNA titers | IFNα | TNFα | |
| T-bet+ B cells | rs = 0.55 P = 0.007 | rs = -0.17 P = 0.4 | rs = -0.11 P = 0.59 | rs = 0.28 P = 0.2 | rs = 0.16 P = 0.4 | rs = 0.36 P = 0.05 | rs = 0.05 P = 0.79 |
| ABCs | rs = 0.3 P = 0.1 | rs = - 0.3 P = 0.154 | rs = -0.1 P = 0.6 | rs = 0.02 P = 0.9 | rs = 0.32 P = 0.13 | rs = 0.35 P = 0.07 | rs = 0.2 P = 0.33 |
| DN | rs = 0.565 P = 0.014 | rs = -0.12 P = 0.64 | rs = -0.014 P = 0.95 | rs = 0.22 P = 0.36 | rs = 0.25 P = 0.31 | rs = 0.26 P = 0.17 | rs = 0.22 P = 0.28 |
| DN2 | rs = 0.59 P = 0.012 | rs = -0.218 P = 0.4 | rs = -0.044 P = 0.86 | rs = 0.17 P = 0.55 | rs = 0.29 P = 0.24 | rs = 0.25 P = 0.19 | rs = 0.18 P = 0.36 |
| SLEDAI | C3 | C4 | ANA titers | Anti- dsDNA titers | IFNα | TNFα | |
| T-bet+ B cells | rs = 0.55 P = 0.007 | rs = -0.17 P = 0.4 | rs = -0.11 P = 0.59 | rs = 0.28 P = 0.2 | rs = 0.16 P = 0.4 | rs = 0.36 P = 0.05 | rs = 0.05 P = 0.79 |
| ABCs | rs = 0.3 P = 0.1 | rs = - 0.3 P = 0.154 | rs = -0.1 P = 0.6 | rs = 0.02 P = 0.9 | rs = 0.32 P = 0.13 | rs = 0.35 P = 0.07 | rs = 0.2 P = 0.33 |
| DN | rs = 0.565 P = 0.014 | rs = -0.12 P = 0.64 | rs = -0.014 P = 0.95 | rs = 0.22 P = 0.36 | rs = 0.25 P = 0.31 | rs = 0.26 P = 0.17 | rs = 0.22 P = 0.28 |
| DN2 | rs = 0.59 P = 0.012 | rs = -0.218 P = 0.4 | rs = -0.044 P = 0.86 | rs = 0.17 P = 0.55 | rs = 0.29 P = 0.24 | rs = 0.25 P = 0.19 | rs = 0.18 P = 0.36 |
Statistical significant data are presented in red. rs: Spearman’s rank correlation coefficient, P: P value for statistical significance. ABCs: CD45+CD19+CD11c+CD21−T-bet+, DN: CD45+CD19+IgD-CD27− T-bet+, DN2: CXCR5− DN (extrafollicular DN).
correlations between T-bet+ B cell populations and the SLEDAI scores of the patients, complement components C3 and C4, ANA and anti-dsDNA autoantibodies and IFNα and TNFα cytokines
| SLEDAI | C3 | C4 | ANA titers | Anti- dsDNA titers | IFNα | TNFα | |
| T-bet+ B cells | rs = 0.55 P = 0.007 | rs = -0.17 P = 0.4 | rs = -0.11 P = 0.59 | rs = 0.28 P = 0.2 | rs = 0.16 P = 0.4 | rs = 0.36 P = 0.05 | rs = 0.05 P = 0.79 |
| ABCs | rs = 0.3 P = 0.1 | rs = - 0.3 P = 0.154 | rs = -0.1 P = 0.6 | rs = 0.02 P = 0.9 | rs = 0.32 P = 0.13 | rs = 0.35 P = 0.07 | rs = 0.2 P = 0.33 |
| DN | rs = 0.565 P = 0.014 | rs = -0.12 P = 0.64 | rs = -0.014 P = 0.95 | rs = 0.22 P = 0.36 | rs = 0.25 P = 0.31 | rs = 0.26 P = 0.17 | rs = 0.22 P = 0.28 |
| DN2 | rs = 0.59 P = 0.012 | rs = -0.218 P = 0.4 | rs = -0.044 P = 0.86 | rs = 0.17 P = 0.55 | rs = 0.29 P = 0.24 | rs = 0.25 P = 0.19 | rs = 0.18 P = 0.36 |
| SLEDAI | C3 | C4 | ANA titers | Anti- dsDNA titers | IFNα | TNFα | |
| T-bet+ B cells | rs = 0.55 P = 0.007 | rs = -0.17 P = 0.4 | rs = -0.11 P = 0.59 | rs = 0.28 P = 0.2 | rs = 0.16 P = 0.4 | rs = 0.36 P = 0.05 | rs = 0.05 P = 0.79 |
| ABCs | rs = 0.3 P = 0.1 | rs = - 0.3 P = 0.154 | rs = -0.1 P = 0.6 | rs = 0.02 P = 0.9 | rs = 0.32 P = 0.13 | rs = 0.35 P = 0.07 | rs = 0.2 P = 0.33 |
| DN | rs = 0.565 P = 0.014 | rs = -0.12 P = 0.64 | rs = -0.014 P = 0.95 | rs = 0.22 P = 0.36 | rs = 0.25 P = 0.31 | rs = 0.26 P = 0.17 | rs = 0.22 P = 0.28 |
| DN2 | rs = 0.59 P = 0.012 | rs = -0.218 P = 0.4 | rs = -0.044 P = 0.86 | rs = 0.17 P = 0.55 | rs = 0.29 P = 0.24 | rs = 0.25 P = 0.19 | rs = 0.18 P = 0.36 |
Statistical significant data are presented in red. rs: Spearman’s rank correlation coefficient, P: P value for statistical significance. ABCs: CD45+CD19+CD11c+CD21−T-bet+, DN: CD45+CD19+IgD-CD27− T-bet+, DN2: CXCR5− DN (extrafollicular DN).
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