| . | Polysubstance (Group 1) n = 67 . | Single Substance (Group 2) n = 68 . | Control (Group 3) n = 36 . | P 1 versus 3 . | P 2 versus 3 . | P 1 + 2 versus 3 . | P 1 versus 2 . |
|---|---|---|---|---|---|---|---|
| Positive DSM-5 domainsa | |||||||
| Depression | 26 (39%) | 30 (44%) | 6 (17%) | .02 | <.01 | >.01 | |
| Anger | 21 (31%) | 22 (32%) | 6 (17%) | .09 | .07 | ||
| Mania | 20 (30%) | 23 (34%) | 3 (8%) | .01 | <.01 | >.01 | |
| Anxiety | 20 (30%) | 30 (44) | 6 (17%) | <.01 | .02 | .09 | |
| Somatic Symptoms | 24 (36%) | 26 (38%) | 7 (19%) | .08 | .05 | .05 | |
| Psychosis | 8 (12%) | 8 (12%) | 0 (0%) | .03 | .03 | .03 | |
| Sleep problems | 20 (30%) | 18 (26%) | 4 (11%) | .03 | .07 | .04 | |
| Impaired memory | 11 (16%) | 14 (21%) | 5 (14%) | ||||
| Repetitive | 10 (15%) | 13 (19) | 0 (0) | .02 | <.01 | >.01 | |
| Thoughts/behaviors | 8 (12%) | 8 (12%) | 1 (3%) | ||||
| Dissociation | 16 (24%) | 20 (29%) | 3 (8) | .05 | .01 | .02 | |
| Personality Functioning | |||||||
| Number of DSM-5 Domains | 2.7 ± 3 | 3.1 ± 3.2 | 1.1 ± 1.6 | <.01 | <.001 | >.001 | |
| ACEs score | 3.9 ± 2.9 | 3.4 ± 2.7 | 2.3 ± 2.8 | <.01 | .06 | .01 | |
| Moderate/high PTSD symptomsb | 33 (49%) | 34 (50%) | 5 (14%) | <.001 | <.001 | >.001 |
| . | Polysubstance (Group 1) n = 67 . | Single Substance (Group 2) n = 68 . | Control (Group 3) n = 36 . | P 1 versus 3 . | P 2 versus 3 . | P 1 + 2 versus 3 . | P 1 versus 2 . |
|---|---|---|---|---|---|---|---|
| Positive DSM-5 domainsa | |||||||
| Depression | 26 (39%) | 30 (44%) | 6 (17%) | .02 | <.01 | >.01 | |
| Anger | 21 (31%) | 22 (32%) | 6 (17%) | .09 | .07 | ||
| Mania | 20 (30%) | 23 (34%) | 3 (8%) | .01 | <.01 | >.01 | |
| Anxiety | 20 (30%) | 30 (44) | 6 (17%) | <.01 | .02 | .09 | |
| Somatic Symptoms | 24 (36%) | 26 (38%) | 7 (19%) | .08 | .05 | .05 | |
| Psychosis | 8 (12%) | 8 (12%) | 0 (0%) | .03 | .03 | .03 | |
| Sleep problems | 20 (30%) | 18 (26%) | 4 (11%) | .03 | .07 | .04 | |
| Impaired memory | 11 (16%) | 14 (21%) | 5 (14%) | ||||
| Repetitive | 10 (15%) | 13 (19) | 0 (0) | .02 | <.01 | >.01 | |
| Thoughts/behaviors | 8 (12%) | 8 (12%) | 1 (3%) | ||||
| Dissociation | 16 (24%) | 20 (29%) | 3 (8) | .05 | .01 | .02 | |
| Personality Functioning | |||||||
| Number of DSM-5 Domains | 2.7 ± 3 | 3.1 ± 3.2 | 1.1 ± 1.6 | <.01 | <.001 | >.001 | |
| ACEs score | 3.9 ± 2.9 | 3.4 ± 2.7 | 2.3 ± 2.8 | <.01 | .06 | .01 | |
| Moderate/high PTSD symptomsb | 33 (49%) | 34 (50%) | 5 (14%) | <.001 | <.001 | >.001 |
Values shown are frequency (column percent) for categorical variables and mean ± standard deviation for continuous variables. P values shown were those ≤.1 for between group comparisons.
Abbreviations: ACEs, Adverse Childhood Experiences; PTSD, posttraumatic stress disorder.
aSymptoms for several days in the past 2 weeks by DSM-5 Self-Rated Level 1 Cross-Cutting Symptom Measure.
bModerate to high symptoms on Post-Traumatic Stress Disorder Checklist-Civilian instrument.
| . | Polysubstance (Group 1) n = 67 . | Single Substance (Group 2) n = 68 . | Control (Group 3) n = 36 . | P 1 versus 3 . | P 2 versus 3 . | P 1 + 2 versus 3 . | P 1 versus 2 . |
|---|---|---|---|---|---|---|---|
| Positive DSM-5 domainsa | |||||||
| Depression | 26 (39%) | 30 (44%) | 6 (17%) | .02 | <.01 | >.01 | |
| Anger | 21 (31%) | 22 (32%) | 6 (17%) | .09 | .07 | ||
| Mania | 20 (30%) | 23 (34%) | 3 (8%) | .01 | <.01 | >.01 | |
| Anxiety | 20 (30%) | 30 (44) | 6 (17%) | <.01 | .02 | .09 | |
| Somatic Symptoms | 24 (36%) | 26 (38%) | 7 (19%) | .08 | .05 | .05 | |
| Psychosis | 8 (12%) | 8 (12%) | 0 (0%) | .03 | .03 | .03 | |
| Sleep problems | 20 (30%) | 18 (26%) | 4 (11%) | .03 | .07 | .04 | |
| Impaired memory | 11 (16%) | 14 (21%) | 5 (14%) | ||||
| Repetitive | 10 (15%) | 13 (19) | 0 (0) | .02 | <.01 | >.01 | |
| Thoughts/behaviors | 8 (12%) | 8 (12%) | 1 (3%) | ||||
| Dissociation | 16 (24%) | 20 (29%) | 3 (8) | .05 | .01 | .02 | |
| Personality Functioning | |||||||
| Number of DSM-5 Domains | 2.7 ± 3 | 3.1 ± 3.2 | 1.1 ± 1.6 | <.01 | <.001 | >.001 | |
| ACEs score | 3.9 ± 2.9 | 3.4 ± 2.7 | 2.3 ± 2.8 | <.01 | .06 | .01 | |
| Moderate/high PTSD symptomsb | 33 (49%) | 34 (50%) | 5 (14%) | <.001 | <.001 | >.001 |
| . | Polysubstance (Group 1) n = 67 . | Single Substance (Group 2) n = 68 . | Control (Group 3) n = 36 . | P 1 versus 3 . | P 2 versus 3 . | P 1 + 2 versus 3 . | P 1 versus 2 . |
|---|---|---|---|---|---|---|---|
| Positive DSM-5 domainsa | |||||||
| Depression | 26 (39%) | 30 (44%) | 6 (17%) | .02 | <.01 | >.01 | |
| Anger | 21 (31%) | 22 (32%) | 6 (17%) | .09 | .07 | ||
| Mania | 20 (30%) | 23 (34%) | 3 (8%) | .01 | <.01 | >.01 | |
| Anxiety | 20 (30%) | 30 (44) | 6 (17%) | <.01 | .02 | .09 | |
| Somatic Symptoms | 24 (36%) | 26 (38%) | 7 (19%) | .08 | .05 | .05 | |
| Psychosis | 8 (12%) | 8 (12%) | 0 (0%) | .03 | .03 | .03 | |
| Sleep problems | 20 (30%) | 18 (26%) | 4 (11%) | .03 | .07 | .04 | |
| Impaired memory | 11 (16%) | 14 (21%) | 5 (14%) | ||||
| Repetitive | 10 (15%) | 13 (19) | 0 (0) | .02 | <.01 | >.01 | |
| Thoughts/behaviors | 8 (12%) | 8 (12%) | 1 (3%) | ||||
| Dissociation | 16 (24%) | 20 (29%) | 3 (8) | .05 | .01 | .02 | |
| Personality Functioning | |||||||
| Number of DSM-5 Domains | 2.7 ± 3 | 3.1 ± 3.2 | 1.1 ± 1.6 | <.01 | <.001 | >.001 | |
| ACEs score | 3.9 ± 2.9 | 3.4 ± 2.7 | 2.3 ± 2.8 | <.01 | .06 | .01 | |
| Moderate/high PTSD symptomsb | 33 (49%) | 34 (50%) | 5 (14%) | <.001 | <.001 | >.001 |
Values shown are frequency (column percent) for categorical variables and mean ± standard deviation for continuous variables. P values shown were those ≤.1 for between group comparisons.
Abbreviations: ACEs, Adverse Childhood Experiences; PTSD, posttraumatic stress disorder.
aSymptoms for several days in the past 2 weeks by DSM-5 Self-Rated Level 1 Cross-Cutting Symptom Measure.
bModerate to high symptoms on Post-Traumatic Stress Disorder Checklist-Civilian instrument.
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