| . | Polysubstance (Group 1) n = 67 . | Single Substance (Group 2) n = 68 . | Control (Group 3) n = 36 . | P 1 versus 3 . | P 2 versus 3 . | P 1 + 2 versus 3 . | P 1 versus 2 . |
|---|---|---|---|---|---|---|---|
| Age, y | 52 ± 12 | 49 ± 14 | 57 ± 13 | .07 | <.01 | .01 | … |
| Sex | |||||||
| Male | 52 (78%) | 52 (76%) | 25 (69%) | … | … | … | … |
| Female | 15 (22%) | 16 (24%) | 11 (31%) | … | … | … | … |
| Gender | … | .04 | .09 | … | |||
| Cisgender | 64 (96%) | 60 (88%) | 34 (100%) | … | … | … | … |
| Transgender | 3 (4%) | 8 (12%) | 0 (0%) | … | … | … | … |
| Race | .07 | … | .06 | … | |||
| Black | 44 (66%) | 43 (63%) | 17 (47%) | … | … | … | … |
| Other | 23 (34%) | 25 (37%) | 19 (53%) | … | … | … | … |
| Ethnicity | |||||||
| Hispanic/Latino | 9 (14%) | 8 (12%) | 5 (14%) | … | … | … | … |
| Sexuality | |||||||
| Gay or lesbian | 29 (43%) | 25 (37%) | 16 (44%) | … | … | … | … |
| Bisexual | 9 (13%) | 9 (13%) | 2 (6%) | … | … | … | … |
| Straight | 21 (31%) | 27 (40%) | 13 (36%) | … | … | … | … |
| Declined/blank | 8 (12%) | 7 (10%) | 5 (14%) | … | … | … | … |
| HIV-related | |||||||
| HIV-1 RNA ≤ 200 cps/mL | 58 (87%) | 63 (93%) | 34 (94%) | … | … | … | … |
| CD4, cells/mm3 | 646 ± 407 | 636 ± 366 | 688 ± 302 | … | … | … | … |
| Financial | |||||||
| No insurance | 2 (3%) | 0 (0%) | 0 (0%) | … | … | … | … |
| Income <$20 000 | 40 (70%) | 35 (61%) | 15 (42%) | <.01 | .06 | .01 | … |
| Has children | 35 (61%) | 29 (48%) | 13 (36%) | .02 | … | .05 | … |
| Substances Used | |||||||
| Cannabis | 57 (53%) | 50 (47%) | - | - | - | - | .09 |
| Cocaine | 50 (81%) | 12 (19%) | - | - | - | - | <.001 |
| Methamphetamine | 19 (95%) | 1 (5%) | - | - | - | - | <.001 |
| Opioids | 16 (89%) | 2 (11%) | - | - | - | - | <.001 |
| Sedatives | 6 (100%) | 0 (0%) | - | - | - | - | .01 |
| Hallucinogens | 6 (100%) | 0 (0%) | - | - | - | - | .01 |
| Daily nicotine | 35 (52%) | 28 (41%) | 6 (17%) | <.01 | .01 | <.01 | … |
| Moderate/high Risk alcohol usea | 35 (56%) | 38 (56%) | 7 (19%) | <.01 | <.01 | <.001 | … |
| . | Polysubstance (Group 1) n = 67 . | Single Substance (Group 2) n = 68 . | Control (Group 3) n = 36 . | P 1 versus 3 . | P 2 versus 3 . | P 1 + 2 versus 3 . | P 1 versus 2 . |
|---|---|---|---|---|---|---|---|
| Age, y | 52 ± 12 | 49 ± 14 | 57 ± 13 | .07 | <.01 | .01 | … |
| Sex | |||||||
| Male | 52 (78%) | 52 (76%) | 25 (69%) | … | … | … | … |
| Female | 15 (22%) | 16 (24%) | 11 (31%) | … | … | … | … |
| Gender | … | .04 | .09 | … | |||
| Cisgender | 64 (96%) | 60 (88%) | 34 (100%) | … | … | … | … |
| Transgender | 3 (4%) | 8 (12%) | 0 (0%) | … | … | … | … |
| Race | .07 | … | .06 | … | |||
| Black | 44 (66%) | 43 (63%) | 17 (47%) | … | … | … | … |
| Other | 23 (34%) | 25 (37%) | 19 (53%) | … | … | … | … |
| Ethnicity | |||||||
| Hispanic/Latino | 9 (14%) | 8 (12%) | 5 (14%) | … | … | … | … |
| Sexuality | |||||||
| Gay or lesbian | 29 (43%) | 25 (37%) | 16 (44%) | … | … | … | … |
| Bisexual | 9 (13%) | 9 (13%) | 2 (6%) | … | … | … | … |
| Straight | 21 (31%) | 27 (40%) | 13 (36%) | … | … | … | … |
| Declined/blank | 8 (12%) | 7 (10%) | 5 (14%) | … | … | … | … |
| HIV-related | |||||||
| HIV-1 RNA ≤ 200 cps/mL | 58 (87%) | 63 (93%) | 34 (94%) | … | … | … | … |
| CD4, cells/mm3 | 646 ± 407 | 636 ± 366 | 688 ± 302 | … | … | … | … |
| Financial | |||||||
| No insurance | 2 (3%) | 0 (0%) | 0 (0%) | … | … | … | … |
| Income <$20 000 | 40 (70%) | 35 (61%) | 15 (42%) | <.01 | .06 | .01 | … |
| Has children | 35 (61%) | 29 (48%) | 13 (36%) | .02 | … | .05 | … |
| Substances Used | |||||||
| Cannabis | 57 (53%) | 50 (47%) | - | - | - | - | .09 |
| Cocaine | 50 (81%) | 12 (19%) | - | - | - | - | <.001 |
| Methamphetamine | 19 (95%) | 1 (5%) | - | - | - | - | <.001 |
| Opioids | 16 (89%) | 2 (11%) | - | - | - | - | <.001 |
| Sedatives | 6 (100%) | 0 (0%) | - | - | - | - | .01 |
| Hallucinogens | 6 (100%) | 0 (0%) | - | - | - | - | .01 |
| Daily nicotine | 35 (52%) | 28 (41%) | 6 (17%) | <.01 | .01 | <.01 | … |
| Moderate/high Risk alcohol usea | 35 (56%) | 38 (56%) | 7 (19%) | <.01 | <.01 | <.001 | … |
Values shown are frequency (column percent) for categorical variables and mean ± standard deviation for continuous variables. P values shown were those ≤.1 for between-group comparisons.
aModerate- to high-risk Substance Involvement Score for alcohol use by NIDA-modified Alcohol, Smoking, and Substance Involvement Screening Test.
| . | Polysubstance (Group 1) n = 67 . | Single Substance (Group 2) n = 68 . | Control (Group 3) n = 36 . | P 1 versus 3 . | P 2 versus 3 . | P 1 + 2 versus 3 . | P 1 versus 2 . |
|---|---|---|---|---|---|---|---|
| Age, y | 52 ± 12 | 49 ± 14 | 57 ± 13 | .07 | <.01 | .01 | … |
| Sex | |||||||
| Male | 52 (78%) | 52 (76%) | 25 (69%) | … | … | … | … |
| Female | 15 (22%) | 16 (24%) | 11 (31%) | … | … | … | … |
| Gender | … | .04 | .09 | … | |||
| Cisgender | 64 (96%) | 60 (88%) | 34 (100%) | … | … | … | … |
| Transgender | 3 (4%) | 8 (12%) | 0 (0%) | … | … | … | … |
| Race | .07 | … | .06 | … | |||
| Black | 44 (66%) | 43 (63%) | 17 (47%) | … | … | … | … |
| Other | 23 (34%) | 25 (37%) | 19 (53%) | … | … | … | … |
| Ethnicity | |||||||
| Hispanic/Latino | 9 (14%) | 8 (12%) | 5 (14%) | … | … | … | … |
| Sexuality | |||||||
| Gay or lesbian | 29 (43%) | 25 (37%) | 16 (44%) | … | … | … | … |
| Bisexual | 9 (13%) | 9 (13%) | 2 (6%) | … | … | … | … |
| Straight | 21 (31%) | 27 (40%) | 13 (36%) | … | … | … | … |
| Declined/blank | 8 (12%) | 7 (10%) | 5 (14%) | … | … | … | … |
| HIV-related | |||||||
| HIV-1 RNA ≤ 200 cps/mL | 58 (87%) | 63 (93%) | 34 (94%) | … | … | … | … |
| CD4, cells/mm3 | 646 ± 407 | 636 ± 366 | 688 ± 302 | … | … | … | … |
| Financial | |||||||
| No insurance | 2 (3%) | 0 (0%) | 0 (0%) | … | … | … | … |
| Income <$20 000 | 40 (70%) | 35 (61%) | 15 (42%) | <.01 | .06 | .01 | … |
| Has children | 35 (61%) | 29 (48%) | 13 (36%) | .02 | … | .05 | … |
| Substances Used | |||||||
| Cannabis | 57 (53%) | 50 (47%) | - | - | - | - | .09 |
| Cocaine | 50 (81%) | 12 (19%) | - | - | - | - | <.001 |
| Methamphetamine | 19 (95%) | 1 (5%) | - | - | - | - | <.001 |
| Opioids | 16 (89%) | 2 (11%) | - | - | - | - | <.001 |
| Sedatives | 6 (100%) | 0 (0%) | - | - | - | - | .01 |
| Hallucinogens | 6 (100%) | 0 (0%) | - | - | - | - | .01 |
| Daily nicotine | 35 (52%) | 28 (41%) | 6 (17%) | <.01 | .01 | <.01 | … |
| Moderate/high Risk alcohol usea | 35 (56%) | 38 (56%) | 7 (19%) | <.01 | <.01 | <.001 | … |
| . | Polysubstance (Group 1) n = 67 . | Single Substance (Group 2) n = 68 . | Control (Group 3) n = 36 . | P 1 versus 3 . | P 2 versus 3 . | P 1 + 2 versus 3 . | P 1 versus 2 . |
|---|---|---|---|---|---|---|---|
| Age, y | 52 ± 12 | 49 ± 14 | 57 ± 13 | .07 | <.01 | .01 | … |
| Sex | |||||||
| Male | 52 (78%) | 52 (76%) | 25 (69%) | … | … | … | … |
| Female | 15 (22%) | 16 (24%) | 11 (31%) | … | … | … | … |
| Gender | … | .04 | .09 | … | |||
| Cisgender | 64 (96%) | 60 (88%) | 34 (100%) | … | … | … | … |
| Transgender | 3 (4%) | 8 (12%) | 0 (0%) | … | … | … | … |
| Race | .07 | … | .06 | … | |||
| Black | 44 (66%) | 43 (63%) | 17 (47%) | … | … | … | … |
| Other | 23 (34%) | 25 (37%) | 19 (53%) | … | … | … | … |
| Ethnicity | |||||||
| Hispanic/Latino | 9 (14%) | 8 (12%) | 5 (14%) | … | … | … | … |
| Sexuality | |||||||
| Gay or lesbian | 29 (43%) | 25 (37%) | 16 (44%) | … | … | … | … |
| Bisexual | 9 (13%) | 9 (13%) | 2 (6%) | … | … | … | … |
| Straight | 21 (31%) | 27 (40%) | 13 (36%) | … | … | … | … |
| Declined/blank | 8 (12%) | 7 (10%) | 5 (14%) | … | … | … | … |
| HIV-related | |||||||
| HIV-1 RNA ≤ 200 cps/mL | 58 (87%) | 63 (93%) | 34 (94%) | … | … | … | … |
| CD4, cells/mm3 | 646 ± 407 | 636 ± 366 | 688 ± 302 | … | … | … | … |
| Financial | |||||||
| No insurance | 2 (3%) | 0 (0%) | 0 (0%) | … | … | … | … |
| Income <$20 000 | 40 (70%) | 35 (61%) | 15 (42%) | <.01 | .06 | .01 | … |
| Has children | 35 (61%) | 29 (48%) | 13 (36%) | .02 | … | .05 | … |
| Substances Used | |||||||
| Cannabis | 57 (53%) | 50 (47%) | - | - | - | - | .09 |
| Cocaine | 50 (81%) | 12 (19%) | - | - | - | - | <.001 |
| Methamphetamine | 19 (95%) | 1 (5%) | - | - | - | - | <.001 |
| Opioids | 16 (89%) | 2 (11%) | - | - | - | - | <.001 |
| Sedatives | 6 (100%) | 0 (0%) | - | - | - | - | .01 |
| Hallucinogens | 6 (100%) | 0 (0%) | - | - | - | - | .01 |
| Daily nicotine | 35 (52%) | 28 (41%) | 6 (17%) | <.01 | .01 | <.01 | … |
| Moderate/high Risk alcohol usea | 35 (56%) | 38 (56%) | 7 (19%) | <.01 | <.01 | <.001 | … |
Values shown are frequency (column percent) for categorical variables and mean ± standard deviation for continuous variables. P values shown were those ≤.1 for between-group comparisons.
aModerate- to high-risk Substance Involvement Score for alcohol use by NIDA-modified Alcohol, Smoking, and Substance Involvement Screening Test.
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