Mean and standard deviation of k-fold AUROC scores for comprehensive and rewired multiplexes.
| . | Rewired 1,000 . | Rewired 1,000 . | Comprehensive net . | Comprehensive net . |
|---|---|---|---|---|
| Gene set . | Mean AUROC . | SD AUROC . | Mean AUROC . | SD AUROC . |
| Abscisic acid | 4.99E-01 | 7.73E-02 | 8.71E-01 | 6.95E-02 |
| Auxin | 4.81E-01 | 4.30E-02 | 8.42E-01 | 3.98E-02 |
| Brassinosteroids | 4.89E-01 | 9.98E-02 | 9.39E-01 | 4.64E-02 |
| Cell wall synthesis | 5.01E-01 | 5.55E-02 | 9.82E-01 | 1.27E-02 |
| CHO metabolism | 4.97E-01 | 4.08E-02 | 9.39E-01 | 3.07E-02 |
| Coldstress | 5.01E-01 | 1.75E-01 | 9.81E-01 | 1.87E-02 |
| Cytokinin | 4.95E-01 | 1.27E-01 | 9.06E-01 | 7.55E-02 |
| Drought salt | 4.98E-01 | 8.28E-02 | 8.69E-01 | 3.91E-02 |
| Ethylene | 4.80E-01 | 6.08E-02 | 8.77E-01 | 4.81E-02 |
| Ethylene and EREBP | 4.93E-01 | 4.05E-02 | 9.25E-01 | 7.18E-03 |
| Fatty acid | 4.91E-01 | 5.46E-02 | 9.32E-01 | 4.25E-02 |
| Flavonoids | 5.02E-01 | 7.09E-02 | 9.48E-01 | 2.88E-02 |
| Gibberelin | 4.78E-01 | 9.54E-02 | 8.50E-01 | 9.14E-02 |
| Glucosinolates | 4.99E-01 | 7.31E-02 | 9.39E-01 | 3.61E-02 |
| Heat stress | 4.67E-01 | 3.90E-02 | 7.66E-01 | 3.48E-02 |
| HeatshockTFs | 4.66E-01 | 3.86E-02 | 7.69E-01 | 5.85E-02 |
| Isoprenoids | 4.99E-01 | 5.62E-02 | 9.85E-01 | 1.51E-02 |
| Jasmonate | 4.98E-01 | 1.21E-01 | 9.93E-01 | 7.94E-03 |
| Lignin biosynthesis | 5.03E-01 | 1.10E-01 | 9.99E-01 | 3.11E-04 |
| Major CHO | 4.90E-01 | 5.87E-02 | 9.14E-01 | 4.16E-02 |
| Phenylpropanoids | 5.01E-01 | 7.70E-02 | 9.97E-01 | 2.33E-03 |
| PS light reaction | 4.53E-01 | 4.63E-02 | 8.41E-01 | 3.27E-02 |
| PS light reaction II | 4.58E-01 | 7.55E-02 | 9.02E-01 | 1.36E-02 |
| Salicylic acid | 5.01E-01 | 1.50E-01 | 8.99E-01 | 1.08E-01 |
| . | Rewired 1,000 . | Rewired 1,000 . | Comprehensive net . | Comprehensive net . |
|---|---|---|---|---|
| Gene set . | Mean AUROC . | SD AUROC . | Mean AUROC . | SD AUROC . |
| Abscisic acid | 4.99E-01 | 7.73E-02 | 8.71E-01 | 6.95E-02 |
| Auxin | 4.81E-01 | 4.30E-02 | 8.42E-01 | 3.98E-02 |
| Brassinosteroids | 4.89E-01 | 9.98E-02 | 9.39E-01 | 4.64E-02 |
| Cell wall synthesis | 5.01E-01 | 5.55E-02 | 9.82E-01 | 1.27E-02 |
| CHO metabolism | 4.97E-01 | 4.08E-02 | 9.39E-01 | 3.07E-02 |
| Coldstress | 5.01E-01 | 1.75E-01 | 9.81E-01 | 1.87E-02 |
| Cytokinin | 4.95E-01 | 1.27E-01 | 9.06E-01 | 7.55E-02 |
| Drought salt | 4.98E-01 | 8.28E-02 | 8.69E-01 | 3.91E-02 |
| Ethylene | 4.80E-01 | 6.08E-02 | 8.77E-01 | 4.81E-02 |
| Ethylene and EREBP | 4.93E-01 | 4.05E-02 | 9.25E-01 | 7.18E-03 |
| Fatty acid | 4.91E-01 | 5.46E-02 | 9.32E-01 | 4.25E-02 |
| Flavonoids | 5.02E-01 | 7.09E-02 | 9.48E-01 | 2.88E-02 |
| Gibberelin | 4.78E-01 | 9.54E-02 | 8.50E-01 | 9.14E-02 |
| Glucosinolates | 4.99E-01 | 7.31E-02 | 9.39E-01 | 3.61E-02 |
| Heat stress | 4.67E-01 | 3.90E-02 | 7.66E-01 | 3.48E-02 |
| HeatshockTFs | 4.66E-01 | 3.86E-02 | 7.69E-01 | 5.85E-02 |
| Isoprenoids | 4.99E-01 | 5.62E-02 | 9.85E-01 | 1.51E-02 |
| Jasmonate | 4.98E-01 | 1.21E-01 | 9.93E-01 | 7.94E-03 |
| Lignin biosynthesis | 5.03E-01 | 1.10E-01 | 9.99E-01 | 3.11E-04 |
| Major CHO | 4.90E-01 | 5.87E-02 | 9.14E-01 | 4.16E-02 |
| Phenylpropanoids | 5.01E-01 | 7.70E-02 | 9.97E-01 | 2.33E-03 |
| PS light reaction | 4.53E-01 | 4.63E-02 | 8.41E-01 | 3.27E-02 |
| PS light reaction II | 4.58E-01 | 7.55E-02 | 9.02E-01 | 1.36E-02 |
| Salicylic acid | 5.01E-01 | 1.50E-01 | 8.99E-01 | 1.08E-01 |
This table contains the mean values and standard deviation (SD) of AUROC for RWR_CV Kfold cross-validation for 25 curated gene sets which all share the same MAPMAN term. The mean and SD values for the rewired networks are averages and SD across 1,000 iterations of the RWR_CV Kfold cross-validation in which the edges of each network were rewired for each iteration. Conversely, the mean and SD values for the comprehensive network alone are those pertaining only to the average values across the single RWR_CV Kfold cross-validation (k = 5).
Mean and standard deviation of k-fold AUROC scores for comprehensive and rewired multiplexes.
| . | Rewired 1,000 . | Rewired 1,000 . | Comprehensive net . | Comprehensive net . |
|---|---|---|---|---|
| Gene set . | Mean AUROC . | SD AUROC . | Mean AUROC . | SD AUROC . |
| Abscisic acid | 4.99E-01 | 7.73E-02 | 8.71E-01 | 6.95E-02 |
| Auxin | 4.81E-01 | 4.30E-02 | 8.42E-01 | 3.98E-02 |
| Brassinosteroids | 4.89E-01 | 9.98E-02 | 9.39E-01 | 4.64E-02 |
| Cell wall synthesis | 5.01E-01 | 5.55E-02 | 9.82E-01 | 1.27E-02 |
| CHO metabolism | 4.97E-01 | 4.08E-02 | 9.39E-01 | 3.07E-02 |
| Coldstress | 5.01E-01 | 1.75E-01 | 9.81E-01 | 1.87E-02 |
| Cytokinin | 4.95E-01 | 1.27E-01 | 9.06E-01 | 7.55E-02 |
| Drought salt | 4.98E-01 | 8.28E-02 | 8.69E-01 | 3.91E-02 |
| Ethylene | 4.80E-01 | 6.08E-02 | 8.77E-01 | 4.81E-02 |
| Ethylene and EREBP | 4.93E-01 | 4.05E-02 | 9.25E-01 | 7.18E-03 |
| Fatty acid | 4.91E-01 | 5.46E-02 | 9.32E-01 | 4.25E-02 |
| Flavonoids | 5.02E-01 | 7.09E-02 | 9.48E-01 | 2.88E-02 |
| Gibberelin | 4.78E-01 | 9.54E-02 | 8.50E-01 | 9.14E-02 |
| Glucosinolates | 4.99E-01 | 7.31E-02 | 9.39E-01 | 3.61E-02 |
| Heat stress | 4.67E-01 | 3.90E-02 | 7.66E-01 | 3.48E-02 |
| HeatshockTFs | 4.66E-01 | 3.86E-02 | 7.69E-01 | 5.85E-02 |
| Isoprenoids | 4.99E-01 | 5.62E-02 | 9.85E-01 | 1.51E-02 |
| Jasmonate | 4.98E-01 | 1.21E-01 | 9.93E-01 | 7.94E-03 |
| Lignin biosynthesis | 5.03E-01 | 1.10E-01 | 9.99E-01 | 3.11E-04 |
| Major CHO | 4.90E-01 | 5.87E-02 | 9.14E-01 | 4.16E-02 |
| Phenylpropanoids | 5.01E-01 | 7.70E-02 | 9.97E-01 | 2.33E-03 |
| PS light reaction | 4.53E-01 | 4.63E-02 | 8.41E-01 | 3.27E-02 |
| PS light reaction II | 4.58E-01 | 7.55E-02 | 9.02E-01 | 1.36E-02 |
| Salicylic acid | 5.01E-01 | 1.50E-01 | 8.99E-01 | 1.08E-01 |
| . | Rewired 1,000 . | Rewired 1,000 . | Comprehensive net . | Comprehensive net . |
|---|---|---|---|---|
| Gene set . | Mean AUROC . | SD AUROC . | Mean AUROC . | SD AUROC . |
| Abscisic acid | 4.99E-01 | 7.73E-02 | 8.71E-01 | 6.95E-02 |
| Auxin | 4.81E-01 | 4.30E-02 | 8.42E-01 | 3.98E-02 |
| Brassinosteroids | 4.89E-01 | 9.98E-02 | 9.39E-01 | 4.64E-02 |
| Cell wall synthesis | 5.01E-01 | 5.55E-02 | 9.82E-01 | 1.27E-02 |
| CHO metabolism | 4.97E-01 | 4.08E-02 | 9.39E-01 | 3.07E-02 |
| Coldstress | 5.01E-01 | 1.75E-01 | 9.81E-01 | 1.87E-02 |
| Cytokinin | 4.95E-01 | 1.27E-01 | 9.06E-01 | 7.55E-02 |
| Drought salt | 4.98E-01 | 8.28E-02 | 8.69E-01 | 3.91E-02 |
| Ethylene | 4.80E-01 | 6.08E-02 | 8.77E-01 | 4.81E-02 |
| Ethylene and EREBP | 4.93E-01 | 4.05E-02 | 9.25E-01 | 7.18E-03 |
| Fatty acid | 4.91E-01 | 5.46E-02 | 9.32E-01 | 4.25E-02 |
| Flavonoids | 5.02E-01 | 7.09E-02 | 9.48E-01 | 2.88E-02 |
| Gibberelin | 4.78E-01 | 9.54E-02 | 8.50E-01 | 9.14E-02 |
| Glucosinolates | 4.99E-01 | 7.31E-02 | 9.39E-01 | 3.61E-02 |
| Heat stress | 4.67E-01 | 3.90E-02 | 7.66E-01 | 3.48E-02 |
| HeatshockTFs | 4.66E-01 | 3.86E-02 | 7.69E-01 | 5.85E-02 |
| Isoprenoids | 4.99E-01 | 5.62E-02 | 9.85E-01 | 1.51E-02 |
| Jasmonate | 4.98E-01 | 1.21E-01 | 9.93E-01 | 7.94E-03 |
| Lignin biosynthesis | 5.03E-01 | 1.10E-01 | 9.99E-01 | 3.11E-04 |
| Major CHO | 4.90E-01 | 5.87E-02 | 9.14E-01 | 4.16E-02 |
| Phenylpropanoids | 5.01E-01 | 7.70E-02 | 9.97E-01 | 2.33E-03 |
| PS light reaction | 4.53E-01 | 4.63E-02 | 8.41E-01 | 3.27E-02 |
| PS light reaction II | 4.58E-01 | 7.55E-02 | 9.02E-01 | 1.36E-02 |
| Salicylic acid | 5.01E-01 | 1.50E-01 | 8.99E-01 | 1.08E-01 |
This table contains the mean values and standard deviation (SD) of AUROC for RWR_CV Kfold cross-validation for 25 curated gene sets which all share the same MAPMAN term. The mean and SD values for the rewired networks are averages and SD across 1,000 iterations of the RWR_CV Kfold cross-validation in which the edges of each network were rewired for each iteration. Conversely, the mean and SD values for the comprehensive network alone are those pertaining only to the average values across the single RWR_CV Kfold cross-validation (k = 5).
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