Top features of the Logistic Regression model trained on concept vector representations of the patient notes for different class labels.
| No dementia . | Other dementia . | Alzheimer’s dementia . | Vascular dementia . |
|---|---|---|---|
| Progressive cognitive decline (No) | Poor performance on semantically based tasks (Yes) | Memory loss that may be less prominent than in Alzheimer’s disease (No) | Memory loss that may be less prominent than in Alzheimer’s disease (Yes) |
| Cognitive impairment (No) | Impaired comprehension of words (Yes) | Decreased reflexes (Yes) | Narrowing of the vessel (No) |
| Poor memory (No) | Amnesia (No) | Profound loss in conceptual knowledge or semantic memory (Yes) | Infarcts involving multiple main arterial territories (Yes) |
| Poor concentration (Yes) | Myoclonus (No) | Rapid onset of memory impairment (No) | Poor performance on semantically based tasks (No) |
| History of atherosclerotic risk factors (No) | Bladder dysfunction (Uncertain) | Mental inflexibility (Yes) | History of atherosclerotic risk factors (Yes) |
| Rigidity (No) | Poor concentration (No) | Progressive cognitive decline (Yes) | Forgetfulness (No) |
| Profound loss in conceptual knowledge or semantic memory (No) | Profound loss in conceptual knowledge or semantic memory (Uncertain) | Fluent speech (Uncertain) | Apathy (No) |
| Amnesia (Uncertain) | Large infarcts (Yes) | Visuospatial difficulties (Yes) | Poor performance on neuropsychological tests (No) |
| Substance dependence (Uncertain) | Reduced speech output (Uncertain) | Lack of initiation (Uncertain) | Large infarcts (Uncertain) |
| Subcortical dementia syndrome (No) | Fluent speech (Yes) | Severe forgetfulness (Yes) | Restlessness (No) |
| No dementia . | Other dementia . | Alzheimer’s dementia . | Vascular dementia . |
|---|---|---|---|
| Progressive cognitive decline (No) | Poor performance on semantically based tasks (Yes) | Memory loss that may be less prominent than in Alzheimer’s disease (No) | Memory loss that may be less prominent than in Alzheimer’s disease (Yes) |
| Cognitive impairment (No) | Impaired comprehension of words (Yes) | Decreased reflexes (Yes) | Narrowing of the vessel (No) |
| Poor memory (No) | Amnesia (No) | Profound loss in conceptual knowledge or semantic memory (Yes) | Infarcts involving multiple main arterial territories (Yes) |
| Poor concentration (Yes) | Myoclonus (No) | Rapid onset of memory impairment (No) | Poor performance on semantically based tasks (No) |
| History of atherosclerotic risk factors (No) | Bladder dysfunction (Uncertain) | Mental inflexibility (Yes) | History of atherosclerotic risk factors (Yes) |
| Rigidity (No) | Poor concentration (No) | Progressive cognitive decline (Yes) | Forgetfulness (No) |
| Profound loss in conceptual knowledge or semantic memory (No) | Profound loss in conceptual knowledge or semantic memory (Uncertain) | Fluent speech (Uncertain) | Apathy (No) |
| Amnesia (Uncertain) | Large infarcts (Yes) | Visuospatial difficulties (Yes) | Poor performance on neuropsychological tests (No) |
| Substance dependence (Uncertain) | Reduced speech output (Uncertain) | Lack of initiation (Uncertain) | Large infarcts (Uncertain) |
| Subcortical dementia syndrome (No) | Fluent speech (Yes) | Severe forgetfulness (Yes) | Restlessness (No) |
Each cell contains a concept of the form “The patient exhibits—”. (Yes) indicates the patient exhibits the corresponding clinical feature, (No) indicates the patient does not exhibit the corresponding clinical feature and (Uncertain) indicates the patient may or may not exhibit the corresponding clinical feature.
Top features of the Logistic Regression model trained on concept vector representations of the patient notes for different class labels.
| No dementia . | Other dementia . | Alzheimer’s dementia . | Vascular dementia . |
|---|---|---|---|
| Progressive cognitive decline (No) | Poor performance on semantically based tasks (Yes) | Memory loss that may be less prominent than in Alzheimer’s disease (No) | Memory loss that may be less prominent than in Alzheimer’s disease (Yes) |
| Cognitive impairment (No) | Impaired comprehension of words (Yes) | Decreased reflexes (Yes) | Narrowing of the vessel (No) |
| Poor memory (No) | Amnesia (No) | Profound loss in conceptual knowledge or semantic memory (Yes) | Infarcts involving multiple main arterial territories (Yes) |
| Poor concentration (Yes) | Myoclonus (No) | Rapid onset of memory impairment (No) | Poor performance on semantically based tasks (No) |
| History of atherosclerotic risk factors (No) | Bladder dysfunction (Uncertain) | Mental inflexibility (Yes) | History of atherosclerotic risk factors (Yes) |
| Rigidity (No) | Poor concentration (No) | Progressive cognitive decline (Yes) | Forgetfulness (No) |
| Profound loss in conceptual knowledge or semantic memory (No) | Profound loss in conceptual knowledge or semantic memory (Uncertain) | Fluent speech (Uncertain) | Apathy (No) |
| Amnesia (Uncertain) | Large infarcts (Yes) | Visuospatial difficulties (Yes) | Poor performance on neuropsychological tests (No) |
| Substance dependence (Uncertain) | Reduced speech output (Uncertain) | Lack of initiation (Uncertain) | Large infarcts (Uncertain) |
| Subcortical dementia syndrome (No) | Fluent speech (Yes) | Severe forgetfulness (Yes) | Restlessness (No) |
| No dementia . | Other dementia . | Alzheimer’s dementia . | Vascular dementia . |
|---|---|---|---|
| Progressive cognitive decline (No) | Poor performance on semantically based tasks (Yes) | Memory loss that may be less prominent than in Alzheimer’s disease (No) | Memory loss that may be less prominent than in Alzheimer’s disease (Yes) |
| Cognitive impairment (No) | Impaired comprehension of words (Yes) | Decreased reflexes (Yes) | Narrowing of the vessel (No) |
| Poor memory (No) | Amnesia (No) | Profound loss in conceptual knowledge or semantic memory (Yes) | Infarcts involving multiple main arterial territories (Yes) |
| Poor concentration (Yes) | Myoclonus (No) | Rapid onset of memory impairment (No) | Poor performance on semantically based tasks (No) |
| History of atherosclerotic risk factors (No) | Bladder dysfunction (Uncertain) | Mental inflexibility (Yes) | History of atherosclerotic risk factors (Yes) |
| Rigidity (No) | Poor concentration (No) | Progressive cognitive decline (Yes) | Forgetfulness (No) |
| Profound loss in conceptual knowledge or semantic memory (No) | Profound loss in conceptual knowledge or semantic memory (Uncertain) | Fluent speech (Uncertain) | Apathy (No) |
| Amnesia (Uncertain) | Large infarcts (Yes) | Visuospatial difficulties (Yes) | Poor performance on neuropsychological tests (No) |
| Substance dependence (Uncertain) | Reduced speech output (Uncertain) | Lack of initiation (Uncertain) | Large infarcts (Uncertain) |
| Subcortical dementia syndrome (No) | Fluent speech (Yes) | Severe forgetfulness (Yes) | Restlessness (No) |
Each cell contains a concept of the form “The patient exhibits—”. (Yes) indicates the patient exhibits the corresponding clinical feature, (No) indicates the patient does not exhibit the corresponding clinical feature and (Uncertain) indicates the patient may or may not exhibit the corresponding clinical feature.
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