Main demographical features in iPPSD/PHP children with normal basal CT levels compared with children with elevated CT levels
| . | Normal basal CT (n = 30) . | Elevated basal CT (n = 58) . | . |
|---|---|---|---|
| Sex F (%) | 13 (43.3) | 35 (60.3) | P = .12 |
| Median age at diagnosis, years (IQR) | 12.1 (5.6-14.8) | 4.3 (1.4-8.0) | P < .00 |
| iPPSD2/PHP1A n (%) | 9 (30) | 40 (68.9) | P < .00 |
| iPPSD3/PHP1B n (%) | 8 (26.6) | 8 (13.8) | P = .14 |
| iPPSD/PHP other n (%) | 13 (43.4) | 10 (17.3) | P = .01 |
| No. of resistances | |||
| 0 (%) | 11 (36.7) | 6 (10.3) | P = .00 |
| 1 (%) | 6 (20) | 9 (15.6) | P = .59 |
| 2 (%) | 13 (43.3) | 43 (74.1) | P = .00 |
| . | Normal basal CT (n = 30) . | Elevated basal CT (n = 58) . | . |
|---|---|---|---|
| Sex F (%) | 13 (43.3) | 35 (60.3) | P = .12 |
| Median age at diagnosis, years (IQR) | 12.1 (5.6-14.8) | 4.3 (1.4-8.0) | P < .00 |
| iPPSD2/PHP1A n (%) | 9 (30) | 40 (68.9) | P < .00 |
| iPPSD3/PHP1B n (%) | 8 (26.6) | 8 (13.8) | P = .14 |
| iPPSD/PHP other n (%) | 13 (43.4) | 10 (17.3) | P = .01 |
| No. of resistances | |||
| 0 (%) | 11 (36.7) | 6 (10.3) | P = .00 |
| 1 (%) | 6 (20) | 9 (15.6) | P = .59 |
| 2 (%) | 13 (43.3) | 43 (74.1) | P = .00 |
Abbreviations: CT, calcitonin; iPPSD2, inactivating PTH/PTHrP signaling disorder subtype 2, also known as PHP1A; iPPSD3, inactivating PTH/PTHrP signaling disorder subtype 3, also known as PHP1B; PHP, pseudohypoparathyroidism.
Main demographical features in iPPSD/PHP children with normal basal CT levels compared with children with elevated CT levels
| . | Normal basal CT (n = 30) . | Elevated basal CT (n = 58) . | . |
|---|---|---|---|
| Sex F (%) | 13 (43.3) | 35 (60.3) | P = .12 |
| Median age at diagnosis, years (IQR) | 12.1 (5.6-14.8) | 4.3 (1.4-8.0) | P < .00 |
| iPPSD2/PHP1A n (%) | 9 (30) | 40 (68.9) | P < .00 |
| iPPSD3/PHP1B n (%) | 8 (26.6) | 8 (13.8) | P = .14 |
| iPPSD/PHP other n (%) | 13 (43.4) | 10 (17.3) | P = .01 |
| No. of resistances | |||
| 0 (%) | 11 (36.7) | 6 (10.3) | P = .00 |
| 1 (%) | 6 (20) | 9 (15.6) | P = .59 |
| 2 (%) | 13 (43.3) | 43 (74.1) | P = .00 |
| . | Normal basal CT (n = 30) . | Elevated basal CT (n = 58) . | . |
|---|---|---|---|
| Sex F (%) | 13 (43.3) | 35 (60.3) | P = .12 |
| Median age at diagnosis, years (IQR) | 12.1 (5.6-14.8) | 4.3 (1.4-8.0) | P < .00 |
| iPPSD2/PHP1A n (%) | 9 (30) | 40 (68.9) | P < .00 |
| iPPSD3/PHP1B n (%) | 8 (26.6) | 8 (13.8) | P = .14 |
| iPPSD/PHP other n (%) | 13 (43.4) | 10 (17.3) | P = .01 |
| No. of resistances | |||
| 0 (%) | 11 (36.7) | 6 (10.3) | P = .00 |
| 1 (%) | 6 (20) | 9 (15.6) | P = .59 |
| 2 (%) | 13 (43.3) | 43 (74.1) | P = .00 |
Abbreviations: CT, calcitonin; iPPSD2, inactivating PTH/PTHrP signaling disorder subtype 2, also known as PHP1A; iPPSD3, inactivating PTH/PTHrP signaling disorder subtype 3, also known as PHP1B; PHP, pseudohypoparathyroidism.
This PDF is available to Subscribers Only
View Article Abstract & Purchase OptionsFor full access to this pdf, sign in to an existing account, or purchase an annual subscription.
