Unadjusted associations between pQCT measured bone parameters and self-reported history of major osteoporotic fracture in Zimbabwean women aged 40-60 yr. Data expressed as odds ratios and 95% CIs per SD increase in pQCT bone parameter and history of not sustaining a MOF.
| n = 384 . | All women . | ||
|---|---|---|---|
| Radius 4% . | OR . | 95% CI . | p-value . |
| Trabecular vBMD | 1.09 | 0.68; 1.74 | .723 |
| Total CSA | 1.41 | 0.86; 2.29 | .172 |
| BSIc | 1.32 | 0.80; 2.17 | .273 |
| Radius 33% | OR | 95% CI | p-value |
| Cortical vBMD | 1.13 | 0.73; 1.76 | .585 |
| Cortical BMC | 1.62 | 1.03; 2.57 | .038 |
| Cortical thickness | 1.27 | 0.81; 1.97 | .295 |
| Total CSA | 1.76 | 1.06; 2.91 | .029 |
| SSI | 1.74 | 1.03; 2.93 | .038 |
| Tibia 4% | OR | 95% CI | p-value |
| Trabecular vBMD | 1.56 | 0.98; 2.50 | .062 |
| Total CSA | 1.34 | 0.82; 2.18 | .245 |
| BSIc | 2.19 | 1.26; 3.80 | .005 |
| Tibia 38% | OR | 95% CI | p-value |
| Cortical vBMD | 1.33 | 0.87; 2.01 | .186 |
| Cortical BMC | 1.55 | 0.96; 2.51 | .071 |
| Cortical thickness | 1.26 | 0.79; 1.99 | .335 |
| Total CSA | 1.61 | 0.95; 2.75 | .079 |
| SSI | 1.90 | 1.08; 3.35 | .026 |
| n = 384 . | All women . | ||
|---|---|---|---|
| Radius 4% . | OR . | 95% CI . | p-value . |
| Trabecular vBMD | 1.09 | 0.68; 1.74 | .723 |
| Total CSA | 1.41 | 0.86; 2.29 | .172 |
| BSIc | 1.32 | 0.80; 2.17 | .273 |
| Radius 33% | OR | 95% CI | p-value |
| Cortical vBMD | 1.13 | 0.73; 1.76 | .585 |
| Cortical BMC | 1.62 | 1.03; 2.57 | .038 |
| Cortical thickness | 1.27 | 0.81; 1.97 | .295 |
| Total CSA | 1.76 | 1.06; 2.91 | .029 |
| SSI | 1.74 | 1.03; 2.93 | .038 |
| Tibia 4% | OR | 95% CI | p-value |
| Trabecular vBMD | 1.56 | 0.98; 2.50 | .062 |
| Total CSA | 1.34 | 0.82; 2.18 | .245 |
| BSIc | 2.19 | 1.26; 3.80 | .005 |
| Tibia 38% | OR | 95% CI | p-value |
| Cortical vBMD | 1.33 | 0.87; 2.01 | .186 |
| Cortical BMC | 1.55 | 0.96; 2.51 | .071 |
| Cortical thickness | 1.26 | 0.79; 1.99 | .335 |
| Total CSA | 1.61 | 0.95; 2.75 | .079 |
| SSI | 1.90 | 1.08; 3.35 | .026 |
Nineteen women reported a previous history of major osteoporotic fracture (15 of whom were WLH).
Abbreviations: vBMD, volumetric BMD; CSA, cross-sectional area; BSIc, bone strength index of compression; SSI, stress–strain index.
Unadjusted associations between pQCT measured bone parameters and self-reported history of major osteoporotic fracture in Zimbabwean women aged 40-60 yr. Data expressed as odds ratios and 95% CIs per SD increase in pQCT bone parameter and history of not sustaining a MOF.
| n = 384 . | All women . | ||
|---|---|---|---|
| Radius 4% . | OR . | 95% CI . | p-value . |
| Trabecular vBMD | 1.09 | 0.68; 1.74 | .723 |
| Total CSA | 1.41 | 0.86; 2.29 | .172 |
| BSIc | 1.32 | 0.80; 2.17 | .273 |
| Radius 33% | OR | 95% CI | p-value |
| Cortical vBMD | 1.13 | 0.73; 1.76 | .585 |
| Cortical BMC | 1.62 | 1.03; 2.57 | .038 |
| Cortical thickness | 1.27 | 0.81; 1.97 | .295 |
| Total CSA | 1.76 | 1.06; 2.91 | .029 |
| SSI | 1.74 | 1.03; 2.93 | .038 |
| Tibia 4% | OR | 95% CI | p-value |
| Trabecular vBMD | 1.56 | 0.98; 2.50 | .062 |
| Total CSA | 1.34 | 0.82; 2.18 | .245 |
| BSIc | 2.19 | 1.26; 3.80 | .005 |
| Tibia 38% | OR | 95% CI | p-value |
| Cortical vBMD | 1.33 | 0.87; 2.01 | .186 |
| Cortical BMC | 1.55 | 0.96; 2.51 | .071 |
| Cortical thickness | 1.26 | 0.79; 1.99 | .335 |
| Total CSA | 1.61 | 0.95; 2.75 | .079 |
| SSI | 1.90 | 1.08; 3.35 | .026 |
| n = 384 . | All women . | ||
|---|---|---|---|
| Radius 4% . | OR . | 95% CI . | p-value . |
| Trabecular vBMD | 1.09 | 0.68; 1.74 | .723 |
| Total CSA | 1.41 | 0.86; 2.29 | .172 |
| BSIc | 1.32 | 0.80; 2.17 | .273 |
| Radius 33% | OR | 95% CI | p-value |
| Cortical vBMD | 1.13 | 0.73; 1.76 | .585 |
| Cortical BMC | 1.62 | 1.03; 2.57 | .038 |
| Cortical thickness | 1.27 | 0.81; 1.97 | .295 |
| Total CSA | 1.76 | 1.06; 2.91 | .029 |
| SSI | 1.74 | 1.03; 2.93 | .038 |
| Tibia 4% | OR | 95% CI | p-value |
| Trabecular vBMD | 1.56 | 0.98; 2.50 | .062 |
| Total CSA | 1.34 | 0.82; 2.18 | .245 |
| BSIc | 2.19 | 1.26; 3.80 | .005 |
| Tibia 38% | OR | 95% CI | p-value |
| Cortical vBMD | 1.33 | 0.87; 2.01 | .186 |
| Cortical BMC | 1.55 | 0.96; 2.51 | .071 |
| Cortical thickness | 1.26 | 0.79; 1.99 | .335 |
| Total CSA | 1.61 | 0.95; 2.75 | .079 |
| SSI | 1.90 | 1.08; 3.35 | .026 |
Nineteen women reported a previous history of major osteoporotic fracture (15 of whom were WLH).
Abbreviations: vBMD, volumetric BMD; CSA, cross-sectional area; BSIc, bone strength index of compression; SSI, stress–strain index.
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